Transferrin Receptor-Mediated Cellular Uptake of Fluorinated Chlorido[<i>N</i>,<i>N</i>′‑bis(salicylidene)-1,2-phenylenediamine]iron(III) Complexes حسب Astrid Dagmar Bernkop-Schnürch (17461895)

الموضوعات:

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects حسب Jie Zhou (28945)

"…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …"

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects حسب Jie Zhou (28945)

"…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …"

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects حسب Jie Zhou (28945)

"…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …"

1466 slows the capsid assembly rate in biochemical Cp149 capsid assembly reactions. حسب Daniel P. Bradley (10306893)

الموضوعات:

1466 inhibits capsid accumulation independent of HBV replication. حسب Daniel P. Bradley (10306893)

الموضوعات:

Compound 390 induces HBV capsid accumulation via an ROS-mediated mechanism. حسب Daniel P. Bradley (10306893)

الموضوعات:

HPD compounds 1736 and 1740 also suppress accumulation of HBV capsids. حسب Daniel P. Bradley (10306893)

الموضوعات:

1466 does not induce disassembly of pre-formed HBV capsids in cell lysates. حسب Daniel P. Bradley (10306893)

الموضوعات:

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study حسب Jemima Opare-Addo (14657955)

الموضوعات:

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study حسب Jemima Opare-Addo (14657955)

الموضوعات:

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study حسب Jemima Opare-Addo (14657955)

الموضوعات:

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study حسب Jemima Opare-Addo (14657955)

الموضوعات:

αHT compound 390 does not affect intracellular capsid accumulation or encapsidated HBV RNA levels in HepG2.2.15 cells. حسب Daniel P. Bradley (10306893)

الموضوعات:

HBV RNaseH inhibitors effects on capsid accumulation occur independent of HBV DNA synthesis. حسب Daniel P. Bradley (10306893)

الموضوعات:

Differences among the classes of CAMs. حسب Daniel P. Bradley (10306893)

الموضوعات:

RAC1 inhibition results in a decrease in oxidative phosphorylation. حسب Shruthi Sriramkumar (12705564)

mGluR5 receptor decreased glycinergic currents. حسب Zi-Yang Zhang (4988555)

"…(<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …"

Comparison of 6 virtues between the two groups [PCOS (n = 49); non-PCOS (n = 50)]. حسب Ghina Ghazeeri (766076)

The cytoplasmic leaflet of the TGN in the Neo1p-depleted <i>cfs1</i>Δ <i>erd1</i>Δ mutant contains PS and decreased level of PI4P. حسب Mamoru Miyasaka (9187916)