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    P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis by Milane, Aline

    Published 2010
    “…As such, efflux pumps are a major obstacle to drug brain distribution. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with little therapeutics available: riluzole is the only drug approved in its treatment. …”
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