eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”

Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis by HASHEM ABU SERHAN (19737499)

“…In vitrectomized eyes, notable decreases were observed: at 30 min, the Ratio of Means (ROM) was 0.81 (95% CI: 0.53; 1.24), indicating a 19% reduction; at 60 min, the ROM of 0.833 (95% CI: 0.77; 0.89) showed a 16.7% reduction; at 90 min, the ROM of 0.757 (95% CI: 0.755; 0.758) corresponded to a 24.3% reduction; at 2 h, the ROM of 0.726 (95% CI: 0.642; 0.820) reflected a 27.4% reduction; at 3 h, the ROM of 0.692 (95% CI: 0.600; 0.797) resulted in a 30.8% reduction; and at 4 h, the ROM of 0.700 (95% CI: 0.363; 1.350) indicated a 30% reduction. …”

Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts by Amr A. Fadle (14150298)

“…The mean Hibbs angle decreased from 153.07 to 142.32° (MD = 10.54°, p < 0.001). …”

Shared Clean Mobility Operations for First-Mile and Last-Mile Public Transit Connections: A Case Study of Doha, Qatar by Afnan Fayez Eliyan (19517221)

“…Moreover, adding the carpooling option can significantly decrease the number of relocations operations at a minimal impact on the commuters’ trip performance.…”

Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials by Pieter Francsois, Fouche

“…This meta-analysis indicated an 11% decrease in the death risk at 1 month after TXA use (odds ratio [OR] 0.89, 95% confidence interval [CI] 0.84 to 0.95) with a number needed to treat of 61 to avoid 1 additional death. …”
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Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies by Umar Nawaz Kayani (17131781)

“…<p dir="ltr">Maintaining a stable exchange rate is a challenging task for the world, especially for developing economies. …”

The Role of Cdc42 and the Cross-talk with RhoA/RhoC during Invadopodia Formation and Invasion in Glioblastoma Multiforme by Maalouf, Hiba

“…To better understand the signaling mechanism underlying Cdc42 positive regulation of invadopodia, we examined the effect of Cdc42 knockdown on the activation of RhoA. We found that Cdc42 depletion decreased RhoA activation which suggests that Cdc42 might be operating upstream of RhoA and regulating invadopodia formation through RhoA. …”
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Automated detection of posterior urethral valves in voiding cystourethrography images: A novel AI-Based pipeline for enhanced diagnosis and classification by Saidul Kabir (15302407)

“…</p><h3>Conclusion </h3><p dir="ltr">PUV detection from VCUG images through automated segmentation and processing can reduce subjectivity and decrease physician workloads. The proposed approach can serve as a foundation for future efforts to fully automate PUV diagnosis and follow-up.…”

Design of an integrated system that combines the steam gasification of plastic waste and a solid oxide fuel cell for sustainable power generation by Khaled Abouemara (17823416)

“…Moreover, using H₂ flow rates to assess SOFC performance reveal increasing activation and ohmic losses (0.04 to 0.09 V and 0 to 0.28 V) with a temperature increase (973–1473 K), while concentration losses decreased (0–0.10 V). …”

Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation by Feng, Samuel

“…A mitohormetic type of relationship was observed with HRV features increasing and then decreasing with increasing HN concentration. …”
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Case report: Safety and efficacy of voxelotor in a patient with sickle cell disease and stage IV chronic kidney disease by Awni Alshurafa (15468195)

“…The data about the safety and efficacy of voxelotor use in chronic kidney disease is limited. Herein we report a 49-year-old man, with sickle cell disease and stage IV chronic kidney disease, who was managed successfully with voxelotor and resulted in decreasing transfusion requirement and vaso-occlusive painful crisis without affecting kidney function.…”

Outcomes of POCUS‐Guided Peripheral Intravenous Access in Difficult Venous Access Patients: A Systematic Review and Meta‐Analysis by Hany A. Zaki (17337673)

“…A systematic review of 15 studies with 1485 patients, sourced from five databases, including PubMed, Cochrane Library, MEDLINE, Web of Science, and Google Scholar, showed POCUS significantly improved success rates (OR: 4.25), first‐attempt success (OR: 5.31), reduced attempts (MD: −0.83), and decreased procedure time (MD: −9.75 min). …”

Developing a Stochastic Model to Predict Cost Overrun due to the Causes of Projects Delay in Oil Fields Construction Industry by ALKHOORI, KHALID ABDUL MAJEED

“…However, most of the causes of cost overrun were found to follow the Log logistic distribution – a family of distribution associated with projects where the risk increases at the initial phase of the project and decreases later on. …”
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Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders by Jaunetta Hill (18255631)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: International Journal of Molecular Sciences<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/ijms242015216" target="_blank">https://dx.doi.org/10.3390/ijms242015216</a></p>…”

FLACON: A Deep Federated Transfer Learning-Enabled Transient Stability Assessment During Symmetrical and Asymmetrical Grid Faults by Mohamed Massaoudi (16888710)

“…<p dir="ltr">Transient stability assessment (TSA) is critical to the reliable operation of a power system against severe fault conditions. …”

An efficient failure-resilient mutual exclusion algorithm for distributed systems leveraging a novel zero-message overlay structure by Mouna Rabhi (17086969)

“…An extensive simulation study demonstrates the viability and efficiency of the proposed algorithm under various node failure models, and relevant metrics (e.g., node queue dimension, number of exchanged messages, and number of disconnected nodes) indicate a graceful degradation in performance with decreasing number of functioning nodes. …”

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia by Ali Zaki Ibrahim (17092957)

“…Computational analyses revealed that the novel variant might have a pathogenic effect that attributed to decreased protein stability, and also has an effect on the biotin carboxylase c-terminal domain of the propionyl carboxylase enzyme. …”

A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats by Firas Feki (17545638)

“…Two aqueous extracts from jojoba (Simmondsia chinensis) seed cake, a simmondsin-rich extract (WE), and a simmondsin-hydrolyzed extract (NE) using Viscozyme L enzyme have been prepared and characterized. …”

Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study by Zlatan Zvizdic (9212371)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: The American Journal of Emergency Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.ajem.2024.05.010" target="_blank">https://dx.doi.org/10.1016/j.ajem.2024.05.010</a></p>…”

Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance by Mohammed Hamidat (3722086)

“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”