Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease حسب Satra Nim (11540447)

"…Furthermore, the peptide inhibitor protects dopaminergic neurons from α-synuclein-mediated degeneration in hermaphroditic C. elegans and preclinical Parkinson’s disease models using female rats. …"

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
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Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation حسب Salman, Zeina

"…Clostridioides difficile infection (CDI) induces severe intestinal inflammation, mediated partly by the NF-κB signaling pathway. Flagellin (FliC), a major component of C. difficile flagella, plays a pivotal role in host-pathogen interactions by inducing inflammation via Toll-like receptor 5 (TLR5). …"
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miRNA-dependent regulation of STIM1 expression in breast cancer حسب Rashmi P. Kulkarni (18618634)

"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"

Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation حسب Kodappully S. Siveen (4246150)

"…Challenging lung airway epithelial cells (AECs) with LBCs decreased (by more than 50%) transepithelial resistance (TER) denoting barrier function alteration. …"

A Severe Case of Overlap of Morphea and Eosinophilic Fasciitis after Burn Injuries حسب Hania Sami (21436013)

"…Another uncommon immune‐mediated connective tissue disease called eosinophilic fasciitis (EF) evolves to cause sclerosis and woody skin induration. …"

Processing Effects on the Oxytetracycline and Tylosin Antibiotic Residues in Middle Eastern Dairy Products حسب Saidy, Liz

"…OTC and TYL were not homogenously distributed between the dairy products. Skimming decreased significantly (p=0.015) TYL concentration by 68.6%. …"
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Throughput of ARQ protocols over Rician, Nakagami and MIMO block fading channels حسب Zummo, Salam A.

"…Keywords: ARQ, throughput, error probability, fading channels, space-time, multiple antennas, transmit diversity, MIMO, Rician, Nakagami.…"
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study حسب Houssein H., Ayoub

"…In the common low-partner-number HSWNs, a significant proportion of NG incidence occurs among FSWs, with NG prevalence 13 times higher among FSWs than clients, and three times higher among clients than their spouses. …"
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The Sources of Variance in the Helsinki Stock Exchange حسب Ben Sita, Bernard

"…Furthermore, inserting the ratio of volume expectation to duration expectation in the ARMA model and the vector error correction (VEC) model, we find that the short-term variance increases (decreases) when more (less) than 1 unit share is traded for 1 unit time.…"
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PROACT: Parallel multi-miner proof of accumulated trust protocol for Internet of Drones حسب Mershad, Khaleel

"…In addition, we propose a new blockchain consensus mechanism in which several miners produce their blocks in parallel, which decreases the time needed to add transactions securely to the blockchain and meets the requirements of delay-sensitive applications. …"
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Indwelling pleural catheters in hepatic hydrothorax حسب Diab, Khalil

"…IPC use may lead to small decreases in BMI and serum albumin levels in patients over time.…"
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Carbonate effects on hexavalent uranium removal from water by nanocrystalline titanium dioxide حسب Wazne, Mahmoud

"…However, the capacity of the nanocrystalline titanium dioxide to remove U(VI) from water decreased in the presence of inorganic carbonate at pH > 6.0. …"
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Effects of Different Processing Methods on the Antibiotic Enrofloxacin Residues Occurrence in Middle Eastern Dairy Products حسب Haddad, Rita

"…Results showed that pasteurization (Holder and High Temperature Short Time) significantly decreased ENF concentration. …"
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Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy حسب Ajaz A. Bhat (12984701)

"…The complex and dynamic interactions of the secreted cytokines, chemokines, growth factors, and their receptors mediate chronic inflammation and immunosuppressive TME favoring tumor progression, metastasis, and decreased response to therapy. …"

Evaluation of Workability and Structuration Rate of Locally Developed 3D Printing Concrete Using Conventional Methods حسب Ahmed, Sara

"…However, for printed specimens, the compressive strength decreased with the increase in a/b ratio due to increased thixotropy. …"
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Effects of Operating Conditions on Water Absorption Capacity of Superabsorbent Hydrogels حسب Abdelwahab, Noun

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A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment حسب Al-Asheh, Sameer

"…Water conductivity, as an indicator of regeneration efficiency, was monitored over time at the different conditions and scenario. In general, it was observed that the conductivity decreases with time until one point is reached and then starts to increase as a result of resin saturation. …"
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Efficiency of commercial banks in Lebanon حسب Djoundourian, Salpie

"…The stochastic production and cost function estimates show that bank level inefficiency effects decreases with time and increases with number of branches, employees per branch, and ratio of staff to operating expenses.…"
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Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS حسب Anna Halama (545988)

"…IS was lower in PCOS (p < 0.001) and was further decreased by the lipid infusion in both PCOS and controls. …"