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221
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. …"
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222
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. …"
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223
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…<h3>Background</h3><p dir="ltr">The neutral amino acid transporter <i>SLC7A8</i> (LAT2) has been described as a key regulator of metabolic adaptation. …"
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224
Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
منشور في 2023"…These changes are associated with reduced OXPHOS gene expression, decreased mitochondrial DNA copy number, and deregulated mitochondrial dynamics, which lead to metabolic reprogramming of NM1 KO cells from OXPHOS to aerobic glycolysis.This, in turn, is associated with a metabolomic profile typical for cancer cells, namely increased amino acid-, fatty acid-, and sugar metabolism, and increased glucose uptake, lactate production, and intracellular acidity. …"
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225
Influence of direct electric field on PMCG-alginate-based microcapsule
منشور في 2022"…Microcapsules showed swelling and decreasing mechanical properties under the applied electric current, and the microcapsule membrane showed anisotropic swelling on the electrode side. …"
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226
Performance and analysis of kappa-carrageenan hydrogel for PFOA-contaminated soil remediation wastewater treatment
منشور في 2024"…Perfluorooctanoic acid is an emerging pollutant with exceptional resistance to degradation and detrimental environmental and health impacts. …"
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227
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. Our findings suggest that direct activation of GLP-1R by Ex-4 reduces OA-induced steatosis in HepG2 cells by reducing fatty acid uptake and transport via FABP1 downregulation.…"
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228
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…Furthermore, confocal microscopy analysis of BODIPY-stained untreated, steatotic, and Ex-4-treated steatotic cells showed that Ex-4 significantly decreases the number of lipid droplets. Fatty acid uptake and transport genes were also affected by MALAT1 knockdown. …"
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229
Spectrofluorometric investigations on the solvent effects on the photocyclization reaction of diclofenac
منشور في 2023"…However, predominant effect of the solvent acidity compared to basicity and polarizability was observed. …"
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230
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
منشور في 2024"…We assessed bone microstructure and BMAT by micro-CT, bone fatty acid and transcriptomic profiles, and bone healing.…"
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231
Two-stage optimisation for malachite green removal using activated date pits
منشور في 2022"…<p>Water pollution, from industry and agriculture, is a major threat to water security in the light of decreasing global potable water resources. Adsorption is one potential treatment technology for the removal of different contaminants from polluted water. …"
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232
Microbiota and sensorial attributes of buffalo meat stored under vacuum packaging: combined impact of marination, citrox and oregano essential oil
منشور في 2023"…The combination of citrox and oregano essential oil (EO) resulted in decreases of 3.0–6.8 and 3.2–6.8 log cfu/g for mesophilic aerobic bacteria, Pseudomonas spp. lactic acid bacteria (LAB), Brochothrix thermosphacta, Enterobacteriaceae, and yeasts, at 4 and 12°C, respectively. …"
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233
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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234
Sulfobetaine-based polydisulfides with tunable upper critical solution temperature (UCST) in water alcohols mixture, depolymerization kinetics and surface wettability
منشور في 2021"…Tunable surface wettability were shown on the grafted polymers. Findings: Decreasing polarity and/or increasing alcohol percentage in the water mixtures induced an increase in the cloud points of the polymers in the solutions. …"
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235
Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride
منشور في 2019"…<p dir="ltr">Aggressive operational conditions e.g. saline media and acidic gases, e.g., CO<sub>2</sub> can increase the corrosion rate of reinforcing steel. …"
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236
Pilot scale evaluation of thin film composite membranes for reducing wastewater volumes: osmotic concentration process
منشور في 2023"…Lastly, cleaning with citric acid succeeded in recovering the initial water flux.…"
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237
Non-diabetic ketoacidosis secondary to primary hyperthyroidism
منشور في 2022"…The blood glucose readings and HbA1c were within normal limits. Also, serum lactic acid and salicylate levels were within the normal range. …"
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238
Clinical and Biochemical Analysis of Glutamate-Cysteine Ligase Deficiency Presented with Late-Onset Spinocerebellar Ataxia and Hemolytic Anemia
منشور في 2024"…Management encompassed a multidisciplinary approach with a trial of high-dose alpha-lipoic acid, glutathione supplement, and physical therapy. …"
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239
Upgrading co-pyrolysis products from ternary biomass: An investigative study of commercial and locally-made catalysts
منشور في 2024"…At higher temperatures, secondary decompositions become prominent, leading to increased gas yields and decreased char and liquid oil yields. The introduction of catalysts generally enhances char yields across both temperature regimes. …"
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240
The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review
منشور في 2024"…The diverse nutrients, such as phycocyanin, gamma-linolenic acid, and vitamin B12, present in spirulina contribute to its cardiometabolic benefits. …"