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121
Post-transcriptional regulation of Pabpn1 by the RNA binding protein HuR
منشور في 2018"…We exploit multiple models including C2C12 myotubes, primary muscle cells, and mice to determine that HuR decreases Pabpn1 expression. Overall, we have uncovered a mechanism in mature muscle that negatively regulates Pabpn1 expression in vitro and in vivo, which could provide insight to future studies investigating therapeutic strategies for OPMD treatment.…"
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122
Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO<sub>2</sub>- saturated saline solution
منشور في 2023"…Nevertheless, the AGGPAM-inhibited solution exhibited a corrosion rate of 26.7 mils per year at 50 °C, which is still lower than that of blank at 25 °C. …"
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123
Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
منشور في 2022"…CO2 is lost from the Gulf due to gas exchange, decreasing DIC, and reducing pCO2 to 464 μatm, similar to that observed. …"
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124
Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…The dominant metabolites present in tested R. coriaria methanolic extract were glycosides of gallic acid (possible gallotannins). In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …"
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125
BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
منشور في 2024"…<p dir="ltr">The need for the early detection of emerging pathogenic viruses and their newer variants has driven the urgent demand for developing point-of-care diagnostic tools. Although nucleic acid-based methods such as reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and loop-mediated isothermal amplification (LAMP) have been developed, a more facile and robust platform is still required. …"
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126
Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia
منشور في 2020"…The physicochemical properties analysis using NCBI amino acid explorer study revealed restrictions in the side chain and loss of hydrogen bonds due to the variant. …"
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127
A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats
منشور في 2022"…After enzyme treatment, simmondsin content decreased from 33.0 % to 3.0 % and glucose content increased from 16.2 % to 27.3 % reflecting simmondsin hydrolysis. …"
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128
Simulation of the size-composition distribution of atmospheric nanoparticles over Europe
منشور في 2018"…The ground level concentrations of particles with a diameter larger than 100 nm (N100) were reproduced with a daily normalized mean error of 40 % and a daily normalized mean bias of −20 %. …"
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129
12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
منشور في 2013"…Treatment of REC with HETE also increased ROS generation and expression of NOX2 and pVEGF-R2 and decreased pSHP1 expression. Treatment of diabetic mice with baicalein significantly decreased retinal HETE, ICAM-1, VCAM-1, IL-6, ROS generation, and NOX2 expression. …"
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130
Portfolio Selection Problem Using CVaR Risk Measures Equipped with DEA, PSO, and ICA Algorithms
منشور في 2022"…It was found that when solving the Mean-CVaR model with evolutionary algorithms, the risk decreased. …"
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131
Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient?
منشور في 2022"…Among climatic variables, mean yearly temperature, mean annual yearly humidity, and mean day length in hours, while in soil variables, organic matter and nitrogen percentage significantly affect the phenological and morphological stages. …"
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132
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
منشور في 2024"…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …"
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133
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
منشور في 2020"…</p> <h2>Results</h2> <p>A total of 4040 patients with fall-related injuries were identified in the study duration which corresponds to the rate of 2.34 per 10,000 population. Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …"
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134
Simulation of microscale particle interactions for optimization of an electrodynamic dust shield to clean desert dust from solar panels
منشور في 2017"…Dust transport distance per 10 cycles generally decreased as cycle frequency increased from 0.5 to 10Hz; however, transport distance per time was largest with an intermediate frequency of 1Hz. …"
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135
Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study
منشور في 2022"…Participants had shown moderate resilience (mean score: 27.64 (SD = 8.31)) and their mean score fear of COVID19 was 15.67 (SD = 6.54). …"
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136
Excess pCO<sub>2</sub> and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
منشور في 2022"…CO<sub>2</sub> is lost from the Gulf due to gas exchange, decreasing DIC, and reducing pCO<sub>2</sub> to 464 μatm, similar to that observed. …"
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137
Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021
منشور في 2025"…In 2019–21, there was an overall decrease in mean annual life expectancy across all countries (overall mean –0·18 years [95% UI –0·22 to –0·13]), with all countries having an absolute fall in life expectancy except for Ireland, Iceland, Sweden, Norway, and Denmark, which showed marginal improvement in life expectancy, and Belgium, which showed no change in life expectancy. …"
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138
Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight
منشور في 2021"…Participants reported increased sitting/reclining time (1.94 h/day mean increase), screen times (2.05 h/day mean increase) with p < 0.001, and decreased exercise time (0.11 h/day mean reduction) with p < 0.001. …"
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139
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
منشور في 2024"…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …"
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140
An efficient failure-resilient mutual exclusion algorithm for distributed systems leveraging a novel zero-message overlay structure
منشور في 2024"…., node queue dimension, number of exchanged messages, and number of disconnected nodes) indicate a graceful degradation in performance with decreasing number of functioning nodes. For instance, for 4,096 nodes organized in a logical tree of arity 4 and with 4 physical nodes for logical node, a negligible number of nodes is disconnected from the tree after 250 epochs when the per-node per-epoch failure probability is p f ≤ 0 . 0008 . …"