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121
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…In summary, EMT-associated overexpression of PD-L1 was partially independent of promoter CpG methylation and more likely to be dependent on posttranslational histone modifications. …"
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122
Optimization of design and operation of solar assisted district cooling systems
منشور في 2020"…Moreover, the existence of the cold-water TES in the system depends on the chosen chiller capacity and the cooling demand of the case study. …"
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123
Turkronicles: diachronic resources for the fast evolving Turkish language
منشور في 2025"…Despite the substantial vocabulary changes, we demonstrate that it is possible to identify old Turkish words that have the same meanings with newly coined ones using word embeddings. …"
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124
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
منشور في 2015"…In vitro experiments also showed that 15-HETE induced HREC migration and tube formation in a NOX-dependent manner. Taken together our data suggest that 12/15-LOX is implicated in DR via a NOX-dependent mechanism.…"
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125
Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
منشور في 2019"…SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …"
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126
Intelligent route to design efficient CO<sub>2</sub> reduction electrocatalysts using ANFIS optimized by GA and PSO
منشور في 2022"…<p dir="ltr">Recently, electrochemical reduction of CO<sub>2</sub> into value-added fuels has been noticed as a promising process to decrease CO<sub>2</sub> emissions. The development of such technology is strongly depended upon tuning the surface properties of the applied electrocatalysts. …"
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127
Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
منشور في 2025"…</p><h3 dir="ltr">Results</h3><p dir="ltr">Our findings demonstrated that AB-FUBINACA induces dose-dependent reduction in testosterone levels in the serum, but not in follicle-stimulating hormone or luteinizing hormone. …"
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128
Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine
منشور في 2024"…Furthermore, we have utilized seven Explainable AI methodologies: Vanilla Gradients (VG), Guided Backpropagation (GBP ), Integrated Gradients ( IG), Guided Integrated Gradients (GIG), SmoothGrad, Gradient-weighted Class Activation Mapping (GCAM), and Guided Grad-CAM (GGCAM) for interpretability examination, aiding in the advancement of dependable and credible automation of healthcare detection of glaucoma.…"
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129
Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain
منشور في 2018"…<h3>Objective</h3><p dir="ltr">Stroke is the main cause of adult disability in the world, leaving more than half of the patients dependent on daily assistance. Understanding the post-stroke biochemical and molecular changes are critical for patient survival and stroke management. …"
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130
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
منشور في 2023"…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …"
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131
A new perspective on cardiovascular drift during prolonged exercise
منشور في 2021"…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …"
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132
Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network
منشور في 2020"…An ANN model consists of three layers, 15 neutrons and 260 <i>epochs</i> accurately predict the CMP with 99.1% of data within ±10% deviation of the mean experimental value. The developed model can be used to forecast the CMP as a function of operating temperature, the substrate composition, and chemical dose, and can be used for scaling-up and cost analysis purposes.…"
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133
Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. …"
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134
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
منشور في 2023"…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …"
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135
Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
منشور في 2024"…Fish fed with CURNPS at various levels exhibited remarkable increase in digestive enzymes (amylase and lipase), immune markers (immunoglobulin G (IgG), lysozyme and phagocytic indices), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)). A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …"
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136
A kinetic evaluation of nutrient and organic matter removal in greywater for green Walls: Assessing the performance of Mineral-Based, Organic, and Waste-Derived plant support media
منشور في 2024"…<p dir="ltr">Greywater recycling provides a means to address rising water demand with reduced environmental impact due to its abundance and lightly polluted nature. …"
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137
Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
منشور في 2025"…It also significantly reduced ad libitum energy intake, decreased hunger, and increased satiety in multiple trials. …"
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138
Mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US: a recent analysis from the National Inpatient Sample
منشور في 2021"…In those patients, the mean (SD) age slightly decreased from 70 (13) years to 69 (13) years (p-trend < 0.001). …"
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139
Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample
منشور في 2020"…In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). …"
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140
Assessment of resin systems as solution for well integrity challenge in carbonate reservoirs
منشور في 2023"…The actual and real-time disputes are mainly dependent on the technical approaches currently available to limit the main causes of well integrity deficiency. …"