Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders حسب Jaunetta Hill (18255631)

"…Specific levels of SP1-driven genes and AD biomarkers such as amyloid precursor protein (APP) and Tau proteins were also decreased as part of this targeted systemic response. …"

Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice حسب Tomas Venit (17248420)

"…These changes are associated with reduced OXPHOS gene expression, decreased mitochondrial DNA copy number, and deregulated mitochondrial dynamics, which lead to metabolic reprogramming of NM1 KO cells from OXPHOS to aerobic glycolysis.This, in turn, is associated with a metabolomic profile typical for cancer cells, namely increased amino acid-, fatty acid-, and sugar metabolism, and increased glucose uptake, lactate production, and intracellular acidity. …"

Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank حسب Al-Hamdani, Mohammed

"…However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R2 = 0.065, ΔF(7, 1724) = 3.34, p = 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. Total body BMD measures also significantly contributed to predicting compromised physical function (R2 = 0.091, ΔF(7, 1724) = 3.762, p < 0.001) after controlling for sociodemographic variables, with a higher total body BMD associated with an increase in compromised physical function.Conclusion: Total body BMD seems to be a more important predictor of stiffness and physical function than specific skeletal sites BMD measures. …"
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Novel polysulfone ultrafiltration membranes incorporating polydopamine functionalized graphene oxide with enhanced flux and fouling resistance حسب Abedalkader Alkhouzaam (15842647)

"…Thus, the pure water flux increased with the addition of rGO-PDA without affecting the rejection properties, while the flux decreased with the embedding of pristine GO particles. …"

Anabolic steroids-induced delirium حسب Mohamed Adil Shah Khoodoruth (14589828)

"…Laboratory results showed a decreased plasma testosterone level of 9.59 nmol/l (10.4–37.4 nmol/l). …"

Road safety and traffic medicine in Iran: Achievements and challenges حسب A. Motevalian (19807242)

"…The number of annual fatalities, which had been on the rise for several decades, reached to the maximum number of over 27500 deaths in 2005. The number decreased to 23000 in 2010 and less than 18000 in 2013. …"

Life cycle assessment of binary recycled ceramic tile and recycled brick waste-based geopolymers حسب Namra Mir (17017734)

"…The LCA analysis is also modelled on a large-scale industrial basis. This results in decreased environmental impacts, and they are 1352 kg CO₂-eq, 3.01 kg SO₂-eq, 0.19 kg N-eq, 6.56E-9 kg CFC 1-eq for GWP, AP, EP, and ODP, respectively.…"

Driving and hypoglycemia حسب Stephen Beer (5480411)

"…Hypoglycemia has been associated with cardiac arrhythmia, a decreased ability to drive and driving mishap. Recent meta-analysis of 15 studies showed a risk road traffic collisions (RTC) of 12-19% greater than general populations. …"

Driving against the clock: Investigating the impacts of time pressure on taxi and non-professional drivers’ safety and compliance حسب Qinaat Hussain (15294164)

"…<p>Drivers often encounter time pressure, which can lead to riskier driving habits, decreased safety margins, and a higher chance of accidents. …"

Vertical Distribution of Phosphorous Fractions and Bioavailability of the Nutrient in the Southern Indian Ocean حسب Muhammed Nayeem Mullungal (21385463)

"…The lower iron bound P fraction at specific depths was attributed to the nature of Fe minerals present within sediments. Decreased level of organic phosphate fraction was due to mineralization. …"

Assessing the Electricity Production Capacities of Emerging Markets for the Sustainable Investments حسب Tamer Aksoy (17947802)

"…First, it would be appropriate to provide tax exemptions to solar energy investors so that the costs of these projects can be decreased. Additionally, investments in solar energy technologies need to be further increased.…"

Engineering the Surface and Mechanical Properties of Water Desalination Membranes Using Ultralong Carbon Nanotubes حسب Yehia M. Manawi (18091207)

"…The water contact angle for PS membranes incorporated with commercial CNT sharply decreased from 73° to 53° (membrane hydrophilization) for membranes with 0.1 and 1.0 wt. % of CNTs, while for the same loading of produced CNTs the water contact angles for the membrane samples increased from 66° to 72°. …"

Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution حسب Kashif Bilal (16896357)

"…Due to the closure of educational institutes, work and learn from home methods have burdened the network resources and considerably decreased a viewer’s Quality of Experience (QoE). The situation calls for innovative techniques to handle the surging load of video traffic on cellular networks. …"

Dynamic Performance Investigation of Solar‐Driven Vapor Absorption Cooling System for Urban Areas حسب Laveet Kumar (11460088)

"…For both flat plate and ETCs, increasing the collector area increased the SF and primary energy savings while increasing the capacity of thermal storage decreased the SF and primary energy savings. For varying thermal storage volumes, the SF varies very little when using flat plate collector but significantly when using ETC. …"

Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model حسب Haissam Abou-Saleh (497840)

"…Although no single sign of cardiotoxicity was observed upon exposure to 200 mg/L of ChNPs, as judged by heartbeat rate, the corrected QT interval (QTc, which measures the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle), maximum cardiac arrest, and ejection fraction assays, the same dosage elicited the impairment of both liver size (decreased liver size, but without steatosis and lipid yolk retention) and neurobehavioral activity (increased movement under different light conditions). …"

Energy saving potential analysis applying factory scale energy audit – A case study of food production حسب Derar Al Momani (17831981)

"…The CO₂ harmful emissions were also decreased. Additionally, it is estimated that switching from the proposed motors to energy-efficient motors will cost less overall over time, saving around 3472.314 JD/month or 0.33576/year on average. …"

Understanding the Molecular Mechanisms of Dysglycemia in Patients with Fanconi-Bickel Syndrome حسب Sanaa Ali Sharari (19953093)

"…Both of the exonic mutations had overexpression of dysfunctional GLUT2 (characterized by decreased glucose uptake activity in PBMCs and mitigated glucose release activity in HEK293T). …"

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity حسب Mohammed R. Shaker (10316180)

"…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …"

Pilot scale evaluation of thin film composite membranes for reducing wastewater volumes: osmotic concentration process حسب Abdelrahman M. Awad (16932519)

"…The membrane achieved a water flux of 10 LMH, which slightly decreased to 9.6 after 48 h of operation, mainly due to inorganic scaling. …"

Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice حسب Ann Van der Jeugd (18629695)

"…Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …"