STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration حسب Ayat S. Hammad (9592374)

"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"

Economic consequences of the covid 19 outbreak حسب Sidik, Hanan

"…The last part of the project is talking about the lockdown in UAE and the decrease of cases of covid and the people in UAE should always have the green pass to access the public sectors finally all the UAE citizens must be vaccinated in order to be safe .…"
احصل على النص الكامل

Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes حسب Abu Saleh Md Moin (6189512)

"…For example, overexpression of α cell specific transcription factor Arx or ablation of Pdx1 resulted in an increase of α cell numbers and a decrease in β cell numbers in rodents. The frequency of α-β double-positive cells was also prominent in human subjects with T2D. …"

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation حسب Abdelilah Arredouani (10914455)

"…Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …"

A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies حسب Y. Tong (18394389)

"…This structural modification also results in a significant decrease of the current. These findings can be useful in understanding the processes during the electron irradiation of molecular SAMs.…"

Effects of organic enrichment on macrofauna community structure: an experimental approach حسب Rodrigo Riera (10476249)

"…AMBI and M-AMBI indices were calculated and a decrease of ecological status was observed in treatment 3x.…"

Dynamic Properties of Water Confined in Graphene-Based Membrane: A Classical Molecular Dynamics Simulation Study حسب One-Sun Lee (1291293)

"…<div><p>We performed molecular dynamics simulations of water molecules inside a hydrophobic membrane composed of stacked graphene sheets. By decreasing the density of water molecules inside the membrane, we observed that water molecules form a droplet through a hydrogen bond with each other in the hydrophobic environment that stacked graphene sheets create. …"

Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet حسب Neelam Iftikhar (14778400)

"…Higher doses of <i>Hibiscus rosa-sinensis</i> significantly decreased the levels of AST, ALT, AP, and SC in comparison with the HFSDC group. …"

Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... حسب Parkes J Kendrick (9714851)

"…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …"

Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease حسب Satra Nim (11540447)

"…Conversely, the peptide inhibitor restores endolysosomal function and thereby decreases α-synuclein levels in multiple models, including female and male human cells harboring disease-causing α-synuclein mutations. …"

Enhanced optical properties of <i>β</i>-Ga₂O₃-_<em>x</em>S_<em>x</em>S: A DFT study حسب G.B. Eshonqulov (22927297)

"…We find that the band gap of the material decreases with increasing sulfur content (from 4.81 eV to 1.59 eV), accompanied by symmetric shifts in both the valence-band offset and the conduction-band edge. …"

Stability enhancement of Al₂O₃, ZnO, and TiO₂ binary nanofluids for heat transfer applications حسب Ans Ahmed Memon (21633692)

"…In the case of (Al₂O₃ + TiO₂), zeta potential decreases slightly from −47.7 to −44.9 mV with the addition of surfactant.…"

Influence of co-current vapor flow on falling film over horizontal tube حسب Furqan Tahir (14429547)

"…In addition, the minimum film thickness decreases by 23.1% for 0.02 kg/(m·s). The high decrement in film thickness can lead to dry patches and scale deposition in case of evaporation.…"

Does a Smile Matter if the Person Is Not Real?: The Effect of a Smile and Stock Photos on Persona Perceptions حسب Joni Salminen (7434770)

"…In contrast, the use of stock photos decreases the perceived similarity with the persona as well as persona credibility, both of which are significant predictors to a willingness to use a persona. …"

AI-driven wearable sensors for postoperative monitoring in surgical patients: A systematic review حسب Muhammad Mohsin Khan (22150360)

"…These methodologies showed decreases in the rates of admission, including the staying duration in Intensive Care Units regarding support via using the AI-built Continuous Remote Early Warning Scoring system. …"

CRISPR-Cas Controls Cryptic Prophages حسب Sooyeon Song (4891132)

"…Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …"

Assessment of Knowledge, Attitude and Practice towards Sustainability Aspects among Higher Education Students in Qatar حسب Shaikha R. Al-Nuaimi (19488232)

"…This value gradually decreases in attitudes and behaviors based on evaluating the pro-sustainability student responses. …"

Energy conversion of heat from abandoned oil wells to mechanical refrigeration - Transient analysis and optimization حسب Mohammed Al-Khawaja (17093017)

"…Results show that at realistic and conservative conditions, the geofluid temperature considerably decreases for the first four months of operation (by an average of 30 °C) and tends to be constant after half a year of operation. …"

Towards Industry 4.0 and Sustainable Manufacturing Applying Environmentally Friendly Machining of a Precipitation Hardened Stainless Steel Using Hot Turning Process حسب Mohammadjafar Hadad (17541345)

"…Moreover, it has been shown that by increasing preheating temperature in hot turning, the hardness of the carbides in the workpiece decreases more than the hardness of the tool substrate and reduces coating materials, consequently reducing cutting tool abrasion wear phenomenon.…"

LDL-C Targets in Secondary Prevention: How Low Should We Go? حسب Karim Bayoumy (3496688)

"…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …"