Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes حسب Abu Saleh Md Moin (6189512)

"…Dedifferentiation is well characterized by the decrease in expression of key β cell markers such as genes encoding major transcription factors, e.g., MafA, NeuroD1, Nkx6.1, and Foxo1, and an increase in atypical or “disallowed” genes for β cells such as lactate dehydrogenase, monocarboxylate transporter MCT1, or progenitor cell genes (Neurog3, Pax4, or Sox9). …"

Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. …"
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Rfg1, a protein related to the hypoxic repressor Rox1 of Saccharomyces cerevisiae, is a novel DNA binding repressor of filamentation in the pathogenic yeast, Candida albicans حسب Khalaf, Roy A.

"…I have identified a repressor of hyphal growth in the pathogenic yeast Candida albicans. …"
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Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells حسب Khoury, Oula

"…Inhibition of autophagy increased cell sensitivity to HuArgI (Co)-PEG5000 indicating that, following arginine deprivation, autophagy plays a protective role in GBM cells. …"
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Tuberculosis following programmed cell death receptor-1 (PD-1) inhibitor in a patient with non-small cell lung cancer. Case report and literature review حسب Aasir M. Suliman (14150217)

"…Nonetheless, tuberculosis (TB) reactivation during their use is increasingly recognized and reported. Herein, we present a 58-year-old lady with advanced non-small cell lung cancer (NSCLC) ALK-negative, EGFR wild, and PD-L1 immune histochemistry (IHC) strongly positive in 95% of tumor cells, on ongoing treatment with Pembrolizumab as a first-line monotherapy. …"

Uhrf1 regulates adipogenesis through GPNMB mediated TGFBeta axis حسب Muneera Vakayil (12037693)

"…</p> <p>Objective: Therefore, here, we aimed to understand the role of Uhrf1 in adipogenesis by studying Uhrf1 loss of function cells.…"

Implicit Vocabulary Acquisition in Project-Based Learning with iPad Technology حسب Nasser, Oumayma

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Identification of potential transcription factors that enhance human iPSC generation حسب Nuha T. Swaidan (18595219)

"…In this study, using RNA-seq platform we have identified and validated the differential gene expression of five transcription factors (TFs) (GBX2, NANOGP8, SP8, PEG3, and ZIC1) that were associated with a remarkable increase in the number of iPSC colonies generated from a patient with Parkinson's disease. …"

Early Nutrition and Risk of Type 1 Diabetes: The Role of Gut Microbiota حسب Elvira Verduci (3171957)

"…<p dir="ltr">Type 1 diabetes (T1D) appears most frequently in childhood, with an alarming increasing incidence in the last decades. …"

Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled trials حسب Ibrahim Elmakaty (14614270)

"…They were associated with an increase in immune-related adverse effects. When used early in the course of TNBC, PD-1/PD-L1 inhibitors exert their maximum benefit. …"

PDX1⁻/NKX6.1⁺ progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells حسب Bushra Memon (4792767)

"…We recently generated novel hPSC-derived pancreatic progenitors, expressing high levels of the transcription factor NKX6.1, in the absence of PDX1 (PDX1⁻/NKX6.1⁺). …"

Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan Sirin (14603304)

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"

Shear performance of FRP Reinforced Deep Beams Made of Ultra High Performance Concrete (UHPC) حسب Salman, Omar

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Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects حسب Majdi Mansouri (16869885)

"…Recently, due to the enhancement of computing capabilities, the increase of the big data use, and the development of effective algorithms, the deep learning (DL) tool has witnessed a great success in data science. …"

Shear Behavior of One-Way Reinforced Concrete Hollow Slabs Voided with PET Void Formers حسب Hasan, Haider H.

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East an... حسب Abdelali Agouni (181926)

"…Acutely, within 48 h of attacks, there was an increase in total endothelial EVs in TIA (6.73 ± 1.77; <i>P</i> = 0.0156; <i>n</i> = 21) and AIS (11.23 ± 1.95; <i>P</i> = 0.0007; <i>n</i> = 66) patients compared to controls (2.04 ± 0.78; <i>n</i> = 24). …"

The Role of DJ-1 in the Glycation Process of Skin and Plasma Proteins in Mice Models حسب Abou Younes, Nour

"…Glycation was classified as an irreversible one-way reaction until the preexisting DJ-1 chaperone protein was identified as a deglycase protein. …"
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Performance analysis and iterative decoding of I-Q trellis space-time codes حسب Zummo, S.A.

"…I-Q trellis codes are known to increase the time diversity of coded systems. …"
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Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells حسب Bekdash, Amira

"…The four cell lines that were not rescued by l-citrulline did not express argininosuccinate synthetase-1, indicating complete arginine auxotrophy. Inhibition of autophagy increased cell sensitivity to HuArgI(Co)-PEG5000 demonstrating the protective role of autophagy following arginine deprivation. …"
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