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401
BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
منشور في 2024"…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …"
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402
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
منشور في 2024"…Pharmacological decrease of MG with Glo1 inducer, trans-resveratrol and hesperetin in combination, offers a novel treatment strategy to counter UPR-related cell dysfunction, particularly in hyperglycemia associated with diabetes.…"
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403
Essays on Renewable Energy Dynamics & Co₂ Emissions: Insights From Selected OIC Countries and World Nations
منشور في 2025"…The results reveal that renewable energy consumption has a negative impact on CO₂ emissions, while real GDP per capita has a positive effect. …"
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404
DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
منشور في 2019"…Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …"
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405
Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
منشور في 2019"…For example, overexpression of α cell specific transcription factor Arx or ablation of Pdx1 resulted in an increase of α cell numbers and a decrease in β cell numbers in rodents. The frequency of α-β double-positive cells was also prominent in human subjects with T2D. …"
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406
Effects of organic enrichment on macrofauna community structure: an experimental approach
منشور في 2013"…AMBI and M-AMBI indices were calculated and a decrease of ecological status was observed in treatment 3x.…"
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407
Economic consequences of the covid 19 outbreak
منشور في 2021"…This report is about economic consequences of the covid-19 and all the rules and regulations that have to apply for all citizens. A description of Covid situation and what are the changes, the flight stops and social distance is a must for all the people, must ware mask and gloves all the time in the second part of the report I talked about the economic situation during the covid 19, fall in the international economics and the progress in the national economics. …"
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408
The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study
منشور في 2020"…Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. …"
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409
Mechanisms behind the immediate effects of Roux-en-Y gastric bypass surgery on type 2 diabetes
منشور في 2013"…This effect is too large to be attributed purely to caloric restriction, so a number of other mechanisms have been proposed. …"
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410
Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study
منشور في 2021"…Higher levels of anger, depression, and general anxiety were prevalent among 1.3% (n=84), 3.9% (n=260), and 1.6% (n=104) of participants, respectively. The mean score for the emotional constructs anger and depression decreased with increased compliance with regulations (<i>P</i>=.04 and <i>P</i>=.11, respectively). …"
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411
Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
منشور في 2014"…Physical exercise reduced the expression of various HSPs in obese to normal levels observed in lean subjects with a parallel decrease in the endogenous levels of IL-6, TNF-α, and RANTES. …"
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412
Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
منشور في 2025"…</p><h3>Results</h3><p dir="ltr">The data demonstrated that the continuous‐bout‐duration (1 × 12 min) of 4vs4 and 3vs3 SSGs was characterized by a significant decrease in total mood disturbance (TMD) compared to 2 × 6 min and 3 × 4 min (4vs4:<i>p</i> < 0.01; 3vs3:<i>p</i> < 0.001). …"
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413
Non-linear relationship between real commodity price volatility and real effective exchange rate: The case of commodity-exporting countries
منشور في 2019"…However, for periods when a country is better integrated financially, we observe a decrease in the impact of real commodity price volatility on REER, especially for the two panels of food and beverages as well as energy. …"
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414
التعليم الديني المسيحي في إندونيسيا: دراسة مادة التربية الدينية في مدرسة إيمانويل الكاثوليكية بجاوا الشرقية...
منشور في 2019"…As a summary, Christian education taught in Christian schools contributes greatly in increasing the number of Christians in Indonesia, which automatically causes the gradual decrease in the number of Muslims.…"
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415
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
منشور في 2023"…Finally, as a definitive and specific way to modulate SLFN11 expression we implemented SLFN11 dCas9 (dead CRISPR associated protein 9) systems to specifically increase or decrease SLFN11 expression.…"
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416
Optimization of Community Integrated Energy System for the State of Qatar Towards Sustainable Development
منشور في 2025"…This is mainly due to the highest emissions per capita records and contribution to the climate change issue. …"
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417
Solar syngas production via methanothermal reduction of strontium oxide
منشور في 2020"…As per the results allied with the equilibrium analysis, a temperature of 2230 K is needed for the complete conversion of SrO into Sr and CH<sub>4</sub> into a mixture of H<sub>2</sub> and CO (syngas). …"
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418
Evaluation of the Surface Integrity and Recast Layer in Electrical Discharge Turning of WC-Co Composites
منشور في 2024"…The results indicated that increasing the rotational speed led to a 10% to 17% decrease in the recast layer thickness and a 14% to 54% reduction in the surface roughness (Ra).…"
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419
An overview of carbon capture technology
منشور في 2012"…The presence of small concentrations of H<sub>2</sub>S (ppm levels) in natural gas results in a sour gas with a drastically-reduced market price and hampered wide utilization. …"
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420
Inflammation-Modulating Biomedical Interventions for Diabetic Wound Healing: An Overview of Preclinical and Clinical Studies
منشور في 2024"…Moreover, the persistent presence of pro-inflammatory cytokines and reactive oxygen species, coupled with a decrease in anti-inflammatory factors, exacerbates the delay in wound healing associated with diabetes. …"