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An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity
منشور في 2010"…In addition, retinoic acid can reverse premalignancy, significantly decrease second primary tumors and provide a treatment benefit in head and neck, lung, esophagus, colon and bladder cancer. …"
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article -
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
منشور في 2024"…Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. Additionally, a decrease in glycochenodeoxycholic acid levels was also triggered by treatment with AuNPs, suggesting modulation of bile acid metabolism with potential effects on lipid homeostasis. …"
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Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel
منشور في 2023"…The PPGs revealed the highest swelling behavior in pH 6–8, decreasing dramatically in more acidic and basic conditions. …"
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Salicylic acid restricts mercury translocation by activating strong antioxidant defense mechanisms in sweet pepper (Capsicum annum L.)
منشور في 2023"…<p dir="ltr">Mercury (Hg) availability in soil and its absorption in plants is seriously concerned for plant production and human health. Salicylic acid (SA) is one of the major plant hormones involved in plant growth and development under biotic and abiotic stress conditions. …"
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Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders
منشور في 2023"…While immunotherapeutic interventions have provided much-awaited solutions, nucleic acid-based tools represent other avenues of intervention; however, these approaches are costly and invasive, and they have serious side effects. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS
منشور في 2018"…<h3>Background</h3><p dir="ltr">Insulin resistance (IR) is the hallmark of PCOS and it is known that exercise may decrease it. What is unknown is whether exercise may mechanistically alter the underlying IR, attenuating the dynamic lipid induced IR in insulin resistant subjects.…"
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Polyaniline/Polystyrene Blends: In-Depth Analysis of the Effect of Sulfonic Acid Dopant Concentration on AC Conductivity Using Broadband Dielectric Spectroscopy
منشور في 2018"…Increasing CSA resulted in a decrease in the AC conductivity of the blends. This behaviour was explained in terms of the availability of a lone pair of electrons of the NH groups in the polyaniline, which are typically attacked by the electron-withdrawing sulfonic acid groups of CSA. …"
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Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
منشور في 2019"…Exercise improved VO2 max (p < 0.01) but did not alter weight. Amino acid profiles were unaffected by an acute increase in IR induced by the lipid infusion. …"
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Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy
منشور في 2022"…HepG2 cells were made steatotic with 400 µM of oleic acid and then treated with 200 nM Ex-4 in order to reduce lipid accumulation. …"
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Development of eco-friendly coating for the fabrication of high performing loose nanofiltration membranes for dye-contaminated wastewater treatment
منشور في 2024"…<p>This study introduces highly efficient loose nanofiltration (LNF) membranes developed through a green synergistic combination of tannic acid (TA) and polyvinyl alcohol (PVA), aimed at addressing the complex challenge of dye/salt fractionation in wastewater treatment. …"
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Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
منشور في 2018"…SLC7A8/SLC3A2 heterodimer is a neutral amino acid exchanger. Here, we demonstrated that SLC7A8 is expressed in the mouse inner ear and that its ablation resulted in ARHL, due to the damage of different cochlear structures. …"
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Zirconium phytate-based proton conductors for high-temperature fuel cell applications
منشور في 2023احصل على النص الكامل
doctoralThesis -
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Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment
منشور في 2020"…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …"
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masterThesis -
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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
منشور في 2023"…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …"
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…The dominant metabolites present in tested R. coriaria methanolic extract were glycosides of gallic acid (possible gallotannins). In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …"
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