Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"

Old subjects with sepsis in the emergency department: trend analysis of case fatality rate حسب Andrea Fabbri (356760)

"…The relative proportion of subjects ≥80 years (overall, 52.9% of cases) and classified as high-risk did not change along the years. CFR decreased only in low-risk subjects (from 13.3 to 5.2%; P < 0.001), and particularly in those aged ≥80 (from 18.2 to 6.6%; P = 0.003), but not in high-risk individuals (from 69.9 to 64.2%; P = 0.713).…"

Ambulatory general urgent clinic: an initiative at the time of COVID-19 pandemic حسب Abdullah Al-Hothi (18505290)

"…Our quality improvement study aimed to decrease the waiting time by 20%, from 21 days in January 2021 to 14 days in April 2021, to evaluate the newly established clinics for urgent referrals during the COVID-19 pandemic, and to assess the physicians’ satisfaction regarding these clinics.…"

Women’s empowerment as a determinant of neonatal mortality in Sub-Saharan Africa: a narrative review focused on Nigeria حسب Joel-Medewase Victor Idowu (22155178)

"…Notably, SSA and South Asia are the regions most lagging behind the Sustainable Development Goal (SDG) 3.2, aiming for <12 neonatal deaths per 1,000 live births by 2030. Within SSA, Nigeria, the most populous country, records the highest number of neonatal deaths annually. …"

Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats حسب Ines Fki (14571855)

"…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …"

Giving fragile bones a stronger foothold حسب Nature Research (16552612)

"…Data on osteoporosis in the Middle East and Africa is scarce, but a report published by the International Osteoporosis Foundation in 2011 said that available evidence indicates that both regions have very high incidences of osteoporotic fractures. Since age is a known risk factor for osteoporosis, incidences are destined to increase in these regions as the percentage of the population older than 50 rises to 40% by 2050. …"

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…Thus, several strategies aimed at increasing SLFN11 are explored to restore chemosensitivity of refractory cancers. …"

A GENERAL REAL-TIME DECODER BASED ON AMD2900 DEVICES حسب SOOMRO, AA

"…Two strategies are adapted to increase throughput of the decoder for real-time decoding. …"
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The political ramifications of forced migration. (c2007) حسب Qumri, Samia

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Education in Tanzania حسب Jane Manyama (22501084)

"…This monumental increase in enrollment rates has led to different challenges, such as overcrowded classrooms, a shortage of trained teachers, inequalities between rural and urban schools, as well as low retention rates for girls due to poverty and early pregnancy. …"

Malva sylvestris water extract حسب Daher, CF

"…About 10% increase in stool water content was observed at highest dose used. …"
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Evaluating impact of electrified vehicles on fuel consumption and CO2 emissions reduction in Lebanese driving conditions using onboard GPS survey حسب Mansour, Charbel

"…This growth is mainly attributed to the raise of daily passenger trips and the increase of car ownership. Moreover, this increase in mobility demand results in severe congestion, mostly in Greater Beirut Area (GBA), which leads to chaotic traffic conditions. …"
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Resiliency Assessment of Road Networks during Mega Sport Events: The Case of FIFA World Cup Qatar 2022 حسب Mohammad Zaher Serdar (17191381)

"…Future research could investigate the use of weighted graphs to increase the accuracy or incorporate different assessment approaches into the framework.…"

Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar حسب Dina Abushanab (10696501)

"…</p><h3> Results</h3><p dir="ltr">The operational costs of the program decreased with maturity by cost savings of QAR125 per 100-patient beds per year. …"

Renal Function Decline in Recipients and Donors of Kidney Grafts حسب Bahous, Sola Aoun

"…Results: Decline in renal function was estimated at 1-year post-transplantation and annually thereafter (median follow-up 8 years, range 3.6-18.3), as the mean of the annualized decrease in the glomerular filtration rate. …"
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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... حسب Saeid Safiri (3713035)

"…Age-standardised death rate decreased by 15.7% (8.6 to 21.0), during the period 1990–2019. …"

Initial risk assessment for pulmonary hypertension in patients with COPD حسب Yammine, Joe

"…Diffusion capacity was lower but did not reach statistical significance (P = 0.07). …"
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The impact of water table fluctuation and salinity on LNAPL distribution and geochemical properties in the smear zone under completely anaerobic conditions حسب Reem Elfatih Ismail (14151663)

"…In fluctuating columns, pore water sulfate decreased in the middle, but in stable columns, it decreased in the first 40 days, which suggested that sulfate was the primary electron donor and sulfate-reducing bacteria were present. …"

Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress حسب Munazza T. Fatima (17280679)

"…We found that SESN2 silencing, though did not specifically induce ER stress, it aggravated the effects of thapsigargin-induced ER stress on oxidative stress and cell survival. …"

Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials حسب Pieter Francsois, Fouche

"…Previous reviews suggested potential TXA benefits but did not consider the latest trials. MethodsA systematic review and bias-adjusted meta-analysis were performed to assess TXA’s effectiveness in emergency traumatic injury settings by pooling estimates from randomized controlled trials. …"
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