The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018) حسب El Jbeily, Elie

"…Furthermore, the contribution of autophagy to arginine depletion-induced cytotoxicity in GBM cells was tested by incubating SF and U87 cells with either HuArgI (Co)-PEG5000 alone and in combination with an autophagy inhibitor (chloroquine or 3- methyladenine) at different time points. Cell death decreased when autophagy was inhibited in SF cells at late time points, thus proving its role in arginine depletion induced cell death. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up حسب Wahiba Elhag (5245547)

"…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …"

Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care حسب Ahmad Kloub (16855149)

"…VTE incidence after protocol implementation decreased from 4 to 1.3% (OR 0.31; 95% CI 0.1–0.9, P = 0.03) without increasing the bleeding rate. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Similarly, KO 47 mice also showed a slower rate of glucose clearance in GTT that was consistent with decreased mRNA expression of the GLUT4 gene in WAT but not in the muscle. …"

Mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US: a recent analysis from the National Inpatient Sample حسب Aya Tabbalat (14150019)

"…In those patients, the mean (SD) age slightly decreased from 70 (13) years to 69 (13) years (p-trend < 0.001). …"

A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge حسب Salim Al Lahham (16515333)

"…Distal necrosis of the patients in this study patients was compared with that in a control of 10 patients in whom we did the conventional FDMA flap. Patients were followed for 6 weeks to trace early postoperative complications (infection, dehiscence, and necrosis) and the establishment of protective sensation (pain and temperature).…"

The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature حسب Maha Sellami (4351159)

"…Strength training for 6-12 weeks did not alter plasma IL-1β, IL-2, IL-6 and TNF-α concentration in healthy elderly adults and patients with chronic-degenerative diseases, while 12 weeks of resistance training decreased muscle TNF-α mRNA in frail elderly individuals. …"

Why do some countries produce more capital intensive output than others? حسب Toukan, Amjad

"…Based on my model I offer an explanation for the variation in physical capital intensity across countries where the model predictions show that a lower quality of governance in a country results in a decrease in the output of capital-intensive goods and an increase in the output of labor-intensive goods. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…</p><h3>Results</h3><p dir="ltr">Our results showed for the first time that severe hypoxia can significantly impair Factor H secretion and CD59 expression in MSCs. …"

Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes حسب Dina Abushanab (10696501)

"…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …"

Fabrication of Ag₂O/WO₃ based sensors for detection of hydrogen sulfide حسب Ahmad Al-Sarraj (17151007)

"…The results can be attributed to the decrease in the energy bandgap due to increasing the Ag content and the strong interaction between the Ag and WO₃ and silver to silver oxide transformation at low annealing temperatures. …"

Diabetic Sensorimotor Polyneuropathy Severity Classification Using Adaptive Neuro Fuzzy Inference System حسب Fahmida Haque (16896489)

"…<p dir="ltr">Diabetic sensorimotor polyneuropathy (DSPN) is an early indicator for non-healing diabetic wounds and diabetic foot ulcers, which account for one of the most common complications of diabetes, leading to increased healthcare cost, decreased quality of life, infections, amputations, and death. …"

SYSTEM DYNAMICS APPROACH FOR WHOLE LIFE CYCLE COST MODELLING OF RESIDENTIAL BUILDING PROJECTS IN UNITED ARAB EMIRATES حسب Sadek, Ahmed

"…This is achieved by applying adjusting risks on project's initial cost at the preconstruction stage with respect to cost and risk behaviours at each time step. Cost impact is following an increasing S-Curve behaviour during CAPEX time and risk impact is following a decreasing S-Curve behaviour during CAPEX lifetime. …"
احصل على النص الكامل

Custom foot orthoses improve performance, but do not modify the biomechanical manifestation of fatigue, during repeated treadmill sprints حسب Olivier Girard (409080)

"…Regardless of footwear condition, mean horizontal forces, step frequency, vertical and leg stiffness decreased from sprint 1 to sprint 8 (all <i>P</i> < 0.001). …"

Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States حسب Abdul Ahad (545575)

"…The analysis of Multiple Cause of Death Files was carried out from 1999 to 2019 to identify fatalities with CVD and PCa listed as either contributory or underlying causes of death. …"

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S. El-Shoukrofy (19646815)

"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound <b>2a</b>. …"

Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar حسب Shuja Mohd Reagu (12051406)

"…</p><h3>Methods</h3><p dir="ltr">A cross sectional survey of perinatal women attending largest maternity centre in Qatar was carried out during the months of October to December 2020. …"

Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making حسب Almutairi, Adel F.

"…In contrary, for every one unit increase in concern scores, the odds of enrollment decreased among study participants by 0.98 [0.97–0.99], adj.P = 0.017. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Rapid mercury removal using living indigenous microalgal communities for water treatment applications حسب Amr Nasr Fekry (22521185)

"…Kinetic studies showed superior correlation with the pseudo-second-order model (R² > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …"

Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases حسب Yousef Yahia (19756989)

"…</p><h3>Results</h3><p dir="ltr">Among 8200 cholecystectomies, 60 cases of MS were identified, with type 1 being the most prevalent (90%). The mean age of the patients was 44 years, with male predominance (75%). …"