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241
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…</p><h3>Methods</h3><p dir="ltr">The Q-OHEP convened on 30 November 2021 for a 3-hour meeting to discuss cancer management, therapeutics, and health economics in Qatar, focusing on four domains: (1) regulatory, (2) procurement, (3) treatment, and (4) patients. …"
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242
Stochastic Programming for Hub Energy Management Considering Uncertainty Using Two-Point Estimate Method and Optimization Algorithm
منشور في 2023"…Additionally, the results show that TPEM approach dependability consideration decreased hub energy’s profit by 8.995% as compared to deterministic planning.…"
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243
Visible Light Photocatalytic Activity of Ag/WO<sub>3</sub> Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark
منشور في 2022"…In addition, the catalyst shows high degradation efficiency and significant dose-dependent inhibition of Gram-negative E. Coli and the Gram-positive S. aureus. …"
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244
The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells
منشور في 2019"…Pb treatment induced oxidative stress by a) increasing the formation of reactive oxygen species and b) decreasing GSTA1 mRNA levels. The toxic effects of Pb on the lung was associated with significant increases in NF-κB and AhR levels which was accompanied with increases in downstream targets genes, iNOS and CYP1A1, respectively. …"
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245
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Interestingly, the silencing of β-catenin with siRNA abolished the effect of Ex-4 on these genes, suggesting dependency on the Wnt/β-catenin pathway. Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"
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246
Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity
منشور في 2023"…Algal-algal bioflocculation efficiency is dependent on the ratio between species with different sizes, increasing with a higher proportion of larger size microalgal cells. …"
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247
Evaluation and Enhancement of Triaging Services Through Quality Improvement Tools at Primary Health Care Level: A Clinical Audit Study
منشور في 2023"…<h3>Background</h3><p dir="ltr">The effective and efficient operation of emergency services at healthcare depends on triage decisions. Successfully implementing a triage system improves patient care, communication, and self-assurance.…"
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248
The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review
منشور في 2024"…Spirulina was effective in reducing body weight, body mass index, and waist circumference, with a potential dose-dependent effect. It also decreased interleukin 6, an important biomarker of body inflammation, by inhibiting NADPH oxidase enzyme, and lowering insulin resistance. spirulina supplementation also reduced triglycerides, low-density lipoprotein cholesterol, and increased high-density lipoprotein cholesterol. …"
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249
A Case Study in Qatar for Optimal Energy Management of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewable Energy and Storage Systems
منشور في 2020"…This interest has focused mainly on reducing the reliance on fossil fuel-based means of transportation and decreasing the harmful emissions produced from this sector. …"
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250
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
منشور في 2022"…Moreover, the cutaneous wound tissues treated with PDL 20, MM, and QM exhibited significantly higher hydroxyproline content than the negative control group, which means a high collagen biosynthesis in wound tissues. …"
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251
Technical assessment of different extraction methods and transcriptome profiling of RNA isolated from small volumes of blood
منشور في 2023"…The quality of gene expression data is strictly dependent on the steps used for the sample collection, extraction, preparation and sequencing. …"
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252
Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome
منشور في 2021"…However, two anticoagulant proteins, vitamin K-dependent protein-S (p < 0.0001) and heparin cofactor-II (p < 0.001) were elevated and prothrombin was decreased (p < 0.05). …"
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253
The promise of tirzepatide: A narrative review of metabolic benefits
منشور في 2025"…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. Furthermore, limited evidence showed that lost body weight may be primarily due to fat mass reduction. …"
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254
Automatic image quality evaluation in digital radiography using for‐processing and for‐presentation images
منشور في 2024"…The effect that changes in exposure parameters and examination protocol had on IQ‐scores were different depending on the IQ metric and image type. The expected positive effect that increasing IAK and decreasing tube potential should have on IQ was clearly exhibited in two IQ metrics only, the signal difference‐to‐noise‐ratio (SDNR) and the detectability index (d’), for both image types. …"
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255
Probing deposition temperature effects and computational analysis of DC-sputtered tungsten (W) thin films for CZTS based solar cells
منشور في 2025"…FESEM images confirm the microstructural dependency on the substrate temperature. Electrical measurements were conducted, and the measured carrier concentration was around 10¹⁴ cm⁻³, increasing with temperature up to 200 °C before decreasing again. …"
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256
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
منشور في 2021"…Treatment of HRECs with HG increased intracellular ROS levels and promoted phenotype shifting towards EndMT, evidenced by decreased expression of endothelial markers concomitant with increased expression of mesenchymal ones. …"
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257
Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
منشور في 2023"…Patient satisfaction from the provided interventions/services was determined by means of an overall rating. The correlation between practiced roles and patient satisfaction with received interventions/services was determined.…"
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258
COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
منشور في 2020"…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …"
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259
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…</p><h3>Methods</h3><p dir="ltr">We performed an ecological study using VR data ranging from 2000 to 2017, dependent on individual country data availability. …"
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260
A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
منشور في 2022"…This trend was similar for all pipe eccentricities at any inclination angles, however, the critical rotational speed at which the pressure loss started to increase was found to be dependent on both the inclination angle and eccentricity. …"