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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…In vitro experiments also showed that 15-HETE induced HREC migration and tube formation in a NOX-dependent manner. Taken together our data suggest that 12/15-LOX is implicated in DR via a NOX-dependent mechanism.…”
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122
The Economic Impact of Optimizing a COVID-19 Management Protocol in Pre-Existing Cardiovascular Disease Patients
Published 2023“…Overall, regardless of critical care status, the optimization of the initial COVID-19 protocols in patients with preexisting CVD did not reduce overall health care costs, but increased it by QAR80,529 (USD 22,117) per patient.…”
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123
Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
Published 2025“…Multiple linear regression was used to examine associations between sociodemographic factors, total body BMD and BMD related to specific skeletal sites (including femoral (femoral neck and trochanter), trunk, pelvis and total spine), and the three WOMAC subscales (pain, stiffness, and physical function).Results: After controlling for sociodemographic variables, total body and specific BMD measures did not predict pain. However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R2 = 0.065, ΔF(7, 1724) = 3.34, p = 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. …”
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124
Understanding the Molecular Mechanisms of Dysglycemia in Patients with Fanconi-Bickel Syndrome
Published 2023“…However, in the patient with the intronic mutation, the mutation did not affect the GLUT2 coding sequence or its expression; glucose uptake activity was also intact. …”
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125
Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
Published 2019“…SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …”
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126
Intelligent route to design efficient CO<sub>2</sub> reduction electrocatalysts using ANFIS optimized by GA and PSO
Published 2022“…<p dir="ltr">Recently, electrochemical reduction of CO<sub>2</sub> into value-added fuels has been noticed as a promising process to decrease CO<sub>2</sub> emissions. The development of such technology is strongly depended upon tuning the surface properties of the applied electrocatalysts. …”
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127
Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
Published 2025“…</p><h3 dir="ltr">Results</h3><p dir="ltr">Our findings demonstrated that AB-FUBINACA induces dose-dependent reduction in testosterone levels in the serum, but not in follicle-stimulating hormone or luteinizing hormone. …”
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128
Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine
Published 2024“…Furthermore, we have utilized seven Explainable AI methodologies: Vanilla Gradients (VG), Guided Backpropagation (GBP ), Integrated Gradients ( IG), Guided Integrated Gradients (GIG), SmoothGrad, Gradient-weighted Class Activation Mapping (GCAM), and Guided Grad-CAM (GGCAM) for interpretability examination, aiding in the advancement of dependable and credible automation of healthcare detection of glaucoma.…”
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129
Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies
Published 2023“…However, the result suggests that decreased volatility stimulates Malaysia’s exports. …”
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130
Ozone and ozone/hydrogen peroxide treatment to remove gemfibrozil and ibuprofen from treated sewage effluent: Factors influencing bromate formation
Published 2020“…Bromate formation was decreased to 0.012 mg/L when the pH was increased to 9. …”
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131
Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages
Published 2020“…Notably, patients with advanced disease stages showed significantly higher levels of GMCs compared to early stages in whole blood, but PBMCs and tumor-infiltrating myeloid cells did not show any significant differences. Lastly, we found that levels of GMCs decreased, while IMCs increased in the TME with tumor budding. …”
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132
AI-driven wearable sensors for postoperative monitoring in surgical patients: A systematic review
Published 2025“…</p><h3>Methods</h3><p dir="ltr">We did a Systematic review on literature published between 2000 and 2024 English articles or those with text English translations. …”
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Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain
Published 2018“…<h3>Objective</h3><p dir="ltr">Stroke is the main cause of adult disability in the world, leaving more than half of the patients dependent on daily assistance. Understanding the post-stroke biochemical and molecular changes are critical for patient survival and stroke management. …”
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134
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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135
A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge
Published 2021“…Distal necrosis of the patients in this study patients was compared with that in a control of 10 patients in whom we did the conventional FDMA flap. Patients were followed for 6 weeks to trace early postoperative complications (infection, dehiscence, and necrosis) and the establishment of protective sensation (pain and temperature).…”
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136
Photocatalytic deposition of cobalt atoms on two-dimensional nanocomposites as efficient visible-light-driven photocatalysts: Experimental study and intelligent modeling
Published 2022“…The Co(76)/TNs /rGO(5) sample recovery and reusage experiments did not show a significant reduction in the photocatalytic performance after five consecutive cycles. …”
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137
Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials
Published 2020“…The sensitivity analysis did not yield a particular group of patients at increased risk of cardiovascular events with ARBs. …”
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138
The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature
Published 2021“…Strength training for 6-12 weeks did not alter plasma IL-1β, IL-2, IL-6 and TNF-α concentration in healthy elderly adults and patients with chronic-degenerative diseases, while 12 weeks of resistance training decreased muscle TNF-α mRNA in frail elderly individuals. …”
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139
A new perspective on cardiovascular drift during prolonged exercise
Published 2021“…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …”
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140
Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network
Published 2020“…An ANN model consists of three layers, 15 neutrons and 260 <i>epochs</i> accurately predict the CMP with 99.1% of data within ±10% deviation of the mean experimental value. The developed model can be used to forecast the CMP as a function of operating temperature, the substrate composition, and chemical dose, and can be used for scaling-up and cost analysis purposes.…”