Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman Alzu'bi (18192898)

“…<p dir="ltr">Chronic use of synthetic <u>cannabinoids</u> (SCs) has been associated with cognitive and behavioural deficits and an increased risk of neuropsychiatric disorders. The underlying molecular and cellular mechanisms of the neurotoxic effects of long-term use of SCs have not been well investigated in the literature. …”

Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice by Tomas Venit (17248420)

“…These changes are associated with reduced OXPHOS gene expression, decreased mitochondrial DNA copy number, and deregulated mitochondrial dynamics, which lead to metabolic reprogramming of NM1 KO cells from OXPHOS to aerobic glycolysis.This, in turn, is associated with a metabolomic profile typical for cancer cells, namely increased amino acid-, fatty acid-, and sugar metabolism, and increased glucose uptake, lactate production, and intracellular acidity. …”

Sulfobetaine-based polydisulfides with tunable upper critical solution temperature (UCST) in water alcohols mixture, depolymerization kinetics and surface wettability by Jozef Kollár (8121347)

“…Tunable surface wettability were shown on the grafted polymers. Findings: Decreasing polarity and/or increasing alcohol percentage in the water mixtures induced an increase in the cloud points of the polymers in the solutions. …”

Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …”
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Fixing a heart valve by Nature Research (16552612)

“…As Antune points out, however, the proportion of repaired valves that need to be replaced later on decreases with surgeons' increasing experience of the procedure. …”

Anabolic steroids-induced delirium by Mohamed Adil Shah Khoodoruth (14589828)

“…Laboratory results showed a decreased plasma testosterone level of 9.59 nmol/l (10.4–37.4 nmol/l). …”

Sustainable Detoxification of Methylene Blue in Wastewater via Tea Residue Adsorption: Optimization and Kinetics by Farah F. Salameh (21797300)

“…At pH 10, the highest adsorption capacity was 24.4 mg/g, and increasing the initial concentration to 500 ppm resulted in an adsorption capacity of 119 mg/g. …”

Characteristics of aerosols and planetary boundary layer dynamics during biomass burning season by Muhammad Zeeshaan Shahid (18131689)

“…<p dir="ltr">The northeastern region of Pakistan (NEP) has experienced increased haze episodes over the past decade, primarily due to enhanced biomass burning activities during the post-monsoon season. …”

Impact of Work-Life Balance on Female Employee Motivation by Haleema Raja (22196926)

“…Therefore, the research suggests that well compensated women can afford to make some compromises in their personal lives. However, with the increasing demand for female labor, it is also clear that women in the workforce must find a way to strike a healthy balance between their professional and personal lives. …”

Synthesis of lithium manganese oxide nanocomposites using microwave‐assisted chemical precipitation technique and their performance evaluation in lithium‐ion batteries by Hanan Abdurehman Tariq (14778361)

“…Compared to pure LMO, the increased electrochemical performance of LMO nanocomposites is due to the introduction of carbon nanostructures (CNTs and GNPs).…”

Analysis of the resilience of the Turkey tourism industry to exogenous shocks: new evidence from a NARDL model by Lanouar Charfeddine (10705000)

“…Interestingly, the results reveal that terrorist attacks decreases have a higher impact on tourism demand compared to the impact of terrorist attacks increases. …”

Probing deposition temperature effects and computational analysis of DC-sputtered tungsten (W) thin films for CZTS based solar cells by M.I. Hossain (22303861)

“…Electrical measurements were conducted, and the measured carrier concentration was around 10¹⁴ cm⁻³, increasing with temperature up to 200 °C before decreasing again. …”

Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose by Roberta Giordo (299595)

“…Treatment of HRECs with HG increased intracellular ROS levels and promoted phenotype shifting towards EndMT, evidenced by decreased expression of endothelial markers concomitant with increased expression of mesenchymal ones. …”

Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review by Amani N. Alansari (19743643)

“…Academic impacts included increased absenteeism (24–29%) and decreased performance.…”

ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder by Sara Cuvertino (18892069)

“…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …”

Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response by Noura Al-Zeheimi (5177066)

“…Kaplan–Meier analysis indicated that patients who received NAC cycles and their excised tumors remained with high levels of NRP-1 had a lower overall survival compared with patients whose tissue NRP-1 decreased post-NAC (log-rank <i>p</i> = 0.049). <i>In vitro</i> validation of the former result showed an increase in the secreted and cellular NRP-1 levels in resistant MDA-MB-231 cells to the most common NAC regimen Adriyamicin/cyclophosphamide+Paclitaxel (AC+PAC). …”

On the Performance of the Node Control Volume Finite Element Method for Modeling Multi-phase Fluid Flow in Heterogeneous Porous Media by Abdul Salam Abd (14151648)

“…Large artificial fluid smearing is observed in coarse meshes; however, it decreases with the increase in mesh resolution. These findings prompt the use of high-resolution meshes for the method and the need for development of novel numerical methods to address this unphysical flow.…”

Successful minimally invasive management of nonvascular grade IV blunt renal trauma with complete transection in a 7-year-old girl by Zlatan Zvizdic (9212371)

“…Although such injuries have a decreased likelihood of spontaneous resolution, not all require open operative repair. …”

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells by Mohamed Qasim, Al-Fahdawi

“…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …”
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Enhanced optical properties of <i>β</i>-Ga₂O₃-_<em>x</em>S_<em>x</em>S: A DFT study by G.B. Eshonqulov (22927297)

“…We find that the band gap of the material decreases with increasing sulfur content (from 4.81 eV to 1.59 eV), accompanied by symmetric shifts in both the valence-band offset and the conduction-band edge. …”