Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine حسب Mariam Ahmed Amin Mohamed Elesnawy (21547187)

"…</p><p dir="ltr">Finally, silencing of <i>PKM2 </i>and<i> TUBA1B</i> in breast cancer cells increased DNA damage and decreased cancer cell survival, validating their role in genomic integrity and mimicking our previous observations following silencing of LDHC. …"

Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome حسب Abu Saleh Md Moin (6189512)

"…When matched for BMI < 25 (16 PCOS, 53 controls) HOMA-IR remained elevated (p < 0.05) and heparin cofactor-II was increased (p < 0.05). In a multivariate analysis accounting for inflammation, insulin resistance and BMI, there was no correlation of PCOS with any of the coagulation proteins. …"

Deep Learning for Dynamic Wildlife Monitoring: A Real-Time Approach حسب Abdul Basit Mughal (22929001)

"…<p dir="ltr">With the rapid amount of deforestation around the world, wild animals lose their habitat and move closer to human settlements, leading to increased human-wildlife conflict and the loss of important human lives, livestock, and rare wild animal species. …"

A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats حسب Firas Feki (17545638)

"…After enzyme treatment, simmondsin content decreased from 33.0 % to 3.0 % and glucose content increased from 16.2 % to 27.3 % reflecting simmondsin hydrolysis. …"

Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat حسب Ahmed Hussein (683680)

"…F. tataricum, on the contrary, increased the viscosity readings. The biscuits fortified with <i>F</i>. esculentum and <i>F.…"

Electrochemical and thermodynamic study on the corrosion performance of API X120 steel in 3.5% NaCl solution حسب Khuram Shahzad (575887)

"…The overall results revealed that PEI significantly decreases the corrosion rate of API X120 steel with inhibition efficiency of 94% at a concentration of 100 μmol L⁻¹. …"

Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States حسب Abdul Ahad (545575)

"…</p><h3>Conclusion</h3><p dir="ltr">After decreasing death rates associated with CVD and PCa from 1999 to 2015, a reversal in the trend was observed from 2015 to 2019. …"

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project حسب Mariam Al-Mutawa (18505317)

"…HAPI is a significant patient safety issue in hospitalized patients and can lead to increased healthcare costs and a decreased quality of life for patients . …"

Does Ultrasound Really Good Enough to Evaluate the Pneumothorax in the Emergency Department حسب Atilla Temel (17788481)

"…Thorax ultrasonography is a useful technique with high specificity in diagnosing pneumothorax, but its sensitivity decreases significantly when the size is below 1 cm.…"

Secrecy Performance of a RIS-Assisted Wireless Network: A Comprehensive Analysis Under Outdated CSI حسب Tasneem Alshamaseen (22392382)

"…This resilience indicates that the system can reduce channel estimation frequency to reconfigure the RIS, thus decreasing overall system overhead and complexity and improving energy efficiency. …"

The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar حسب Dina Abushanab (10696501)

"…The operational costs decreased with the developed ASP. Whereas antimicrobial consumption and resource utilisation, and their associated costs, appear to have declined with the developed ASP, with a cost saving of QAR458 (US$125) per 100-patient beds, the avoided cost was negative, by QAR4,807 (US$1,317) per 100-patient beds, adding to a total QAR4,224 (US$1,160) increase in the 100-patient beds cost after ASP development.…"

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 حسب LBD Double Burden of Malnutrition Collaborators (18567880)

"…Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. …"

Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study حسب Rajesh, Sharma

"…Between 1990 and 2019, deaths due to 17 of the 29 cancers either doubled or more, and 20 of the 29 cancers underwent an increase of 150% or more in terms of new cases. Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... حسب Haidong Wang (47381)

"…HALE increased in 202 of 204 countries and territories between 2000 and 2019. …"

Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19 حسب Abu Saleh Md Moin (6189512)

"…Two potent M1 macrophage activation markers, CXCL9 and CXCL10, were decreased in OT2D. Activated M2 macrophages were characterized by elevated levels of plasma CD163, TFGβ-1, MMP7 and MMP9 in OT2D. …"

COVID-19 biomarkers for severity mapped to polycystic ovary syndrome حسب Abu Saleh Md Moin (6189512)

"…However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …"

Enhanced thermoelectric properties of Bi₂Te_2.55Se_0.45 nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable... حسب Farah M. El-Makaty (14157090)

"…However, adding higher amounts (0.1, 0.5, and 1) decreased the electrical and thermal conductivities due to the dominant effect of bulky precipitates in increasing the scattering of charge carriers and phonons. …"

Application of Fe₃O₄ magnetite nanoparticles grafted in silica (SiO₂) for oil recovery from oil in water emulsions حسب Wamda Faisal Elmobarak (17058024)

"…Using an MD_dose as low as 10 mg/L attained a %_hdem in the range of 93% - 4.3% for O/W mixtures with C_oil < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. The reported %R_oil(p-value <0.05) was >90 ± 0.1 for tests carried out with pH 7 and C_sur0.1 g/L and declined at higher pH and Csur to % 86.5 due to the increase in emulsion stability. …"

The Trace Element Composition of Size Fractionated Suspended Particulate Matter Samples from the Qatari EEZ of the Arabian Gulf: The Role of Atmospheric Dust حسب Oguz Yigiterhan (14151006)

"…The excess concentrations, relative to average dust, for most elements (except Cd) decreased with distance from shore, which may be due to differences in biology, currents, proximity to the coast or interannual processes.…"

Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems حسب Local Burden of Disease HIV Collaborators (13279180)

"…</p><h3>Results</h3><p dir="ltr">All countries displayed over a 40-fold difference in HIV mortality between municipalities with the highest and lowest age-standardized HIV mortality rate in the last year of study for men, and over a 20-fold difference for women. Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. …"