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121
Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
منشور في 2023"…Here we performed a high-throughput, proteome-wide peptide screen to identify protein-protein interaction inhibitors that reduce α-synuclein oligomer levels and their associated cytotoxicity. …"
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122
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
منشور في 2021"…In addition, it discusses the wide range of changes and intracellular signaling pathways that occur in the TME. …"
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123
Identification of groundwater potential recharge zones in a Tunisian anthropogenic coastal region: Insights from multi-criteria decision-making techniques
منشور في 2023"…This is the case for the Chiba coastal region (northeast of Tunisia) where excessive extraction of GW has led to decreasing GW levels and an acceleration of seawater intrusion. …"
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124
A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge
منشور في 2021"…Distal necrosis of the patients in this study patients was compared with that in a control of 10 patients in whom we did the conventional FDMA flap. Patients were followed for 6 weeks to trace early postoperative complications (infection, dehiscence, and necrosis) and the establishment of protective sensation (pain and temperature).…"
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125
Photocatalytic deposition of cobalt atoms on two-dimensional nanocomposites as efficient visible-light-driven photocatalysts: Experimental study and intelligent modeling
منشور في 2022"…The Co(76)/TNs /rGO(5) sample recovery and reusage experiments did not show a significant reduction in the photocatalytic performance after five consecutive cycles. …"
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126
Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials
منشور في 2020"…The sensitivity analysis did not yield a particular group of patients at increased risk of cardiovascular events with ARBs. …"
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127
The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature
منشور في 2021"…Strength training for 6-12 weeks did not alter plasma IL-1β, IL-2, IL-6 and TNF-α concentration in healthy elderly adults and patients with chronic-degenerative diseases, while 12 weeks of resistance training decreased muscle TNF-α mRNA in frail elderly individuals. …"
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128
A new perspective on cardiovascular drift during prolonged exercise
منشور في 2021"…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …"
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129
Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network
منشور في 2020"…An ANN model consists of three layers, 15 neutrons and 260 <i>epochs</i> accurately predict the CMP with 99.1% of data within ±10% deviation of the mean experimental value. The developed model can be used to forecast the CMP as a function of operating temperature, the substrate composition, and chemical dose, and can be used for scaling-up and cost analysis purposes.…"
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130
Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. …"
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131
A kinetic evaluation of nutrient and organic matter removal in greywater for green Walls: Assessing the performance of Mineral-Based, Organic, and Waste-Derived plant support media
منشور في 2024"…<p dir="ltr">Greywater recycling provides a means to address rising water demand with reduced environmental impact due to its abundance and lightly polluted nature. …"
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132
Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
منشور في 2025"…It also significantly reduced ad libitum energy intake, decreased hunger, and increased satiety in multiple trials. …"
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133
Mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US: a recent analysis from the National Inpatient Sample
منشور في 2021"…In those patients, the mean (SD) age slightly decreased from 70 (13) years to 69 (13) years (p-trend < 0.001). …"
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134
Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States
منشور في 2024"…</p><h3>Methods</h3><p dir="ltr">This analysis utilized the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER). …"
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135
Seroprevalence of camel brucellosis in Qatar
منشور في 2022"…<p dir="ltr">Brucellosis is a significant zoonotic disease and one of the most common neglected diseases worldwide. It can infect a wide range of domestic and wild animal species. Infected animals are usually culled, causing substantial economic losses to animal owners and the country’s economy in general. …"
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136
Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
منشور في 2023"…Thymoquinone (THYO) is also effective against a wide range of disorders. Consequently, this study sought out to explore the ameliorative effects of IL-35 and THYO against PAR-induced hepatotoxicity in rats. …"
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137
Characterization of Electronic and Ionic Transport in Li<sub>1-</sub><sub><em>x</em></sub>Ni<sub>0.33</sub>Mn<sub>0.33</sub>Co<sub>0.33</sub>O<sub>2</sub>(NMC<sub>333</sub>) and Li...
منشور في 2016"…The lithium ion diffusivity is at least one order of magnitude lower, and decreases with increasing <i>x</i> to at <i>x</i> = ∼0.5. …"
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138
Mixed siliciclastic-carbonate-evaporite sedimentation in an arid eolian landscape: The Khor Al Adaid tide-dominated coastal embayment, Qatar
منشور في 2020"…The overall landward increase in salinity is accompanied by a decrease in the diversity of benthic fauna and their skeletal remains. …"
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139
Effect of Optimizing Oxygen Saturation Targets on the Incidence of Retinopathy of Prematurity in a Quaternary NICU
منشور في 2022"…Despite a statistically significant increase of 10 percent points in time spent within target SpO2 (91–95%) in the post-intervention phase (p < 0.05), the incidence of severe ROP did not decline. Using a multivariate model, odds of ROP development decreased with gestational age (25%) while increasing with PDA requiring treatment (4.33 times) and glucose ≥10 mg/dL (4.15 times), considering one variable at a time, keeping others constant. …"
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140
Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
منشور في 2024"…</p><h3>Results</h3><p dir="ltr">After controlling for sociodemographic variables, total body and specific BMD measures did not predict pain. However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R<sup>2</sup> = 0.065, ΔF(7, 1724) = 3.34, p= 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. …"