Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling حسب Sabah Akhtar (5809925)

"…SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …"

Nickel toxicology testing in alternative specimen from farm ruminants in a urban polluted environment حسب Zafar Iqbal Khan (21225059)

"…General monitoring of soil and vegetation pollution load, as well as the use of other non-conventional water like canal water for forage irrigation could be a sustainable solution to decrease the access of nickel in the food chain.</p><h2>Other Information</h2> <p> Published in: Journal of King Saud University - Science<br> License: <a href="http://creativecommons.org/licenses/by-nc-nd/4.0/" target="_blank">http://creativecommons.org/licenses/by-nc-nd/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jksus.2024.103520" target="_blank">https://dx.doi.org/10.1016/j.jksus.2024.103520</a></p>…"

A new insight into the separation of oil from oil/water emulsion by Fe₃O₄–SiO₂ nanoparticles حسب Wamda Faisal Elmobarak (17058024)

"…For the oil recovery process, the Fe₃O₄ was applied for the inhibition (i.e., decrease) of oil sedimentation, and the SiO₂ NPs were applied for wettability alteration and IFT reduction. …"

BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells حسب Ali Alhoshani (3720718)

"…</p><h3>Results</h3><p dir="ltr">Treatment of human breast cancer cells with increasing concentrations of VCX caused a significant decrease in cells growth and proliferation. This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …"

A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar حسب Muna Abed Alah (14779534)

"…We found a significant decrease in the intake of vegetables, increases in the intake of soft drinks, fried food, fast food, and sweets, and a reduction in physical activity during schools’ closure compared to before. …"

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis حسب Nabil, Shallik

"…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …"
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The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20... حسب Sudabeh Alatab (11257335)

"…The age-standardised death rate decreased from 0·61 (0·55–0·69) per 100 000 population in 1990 to 0·51 (0·42–0·54) per 100 000 population in 2017. …"

Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study حسب Brit Mollenhauer (482499)

"…The use of common reference CSF samples decreased the differences in α‐synuclein concentration between detection methods and technologies. …"

Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31 حسب Jonathan D. J. Labonne (18090841)

"…RT-qPCR assays revealed that LRRK2 transcripts were dramatically reduced in our microdeletion patient DGDP289A compared to his healthy grandfather with no deletion. The decreased expression of LRRK2 may affect protein–protein interactions between LRRK2 and its binding partners, of which eight have previously been linked to intellectual disability. …"

Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch حسب Zhang, Wenhao

"…VAMP7 knockout also decreased IL-4 and LTC4 release from basophils. Additionally, OSM downregulated barrier proteins and upregulated pruriceptors in keratinocytes; however, these effects were reversed by SC144, which restored skin barrier function in AIF without affecting itch response in either model. …"
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Advanced direct air capture of CO₂ using air conditioning systems: a life cycle assessment حسب Namra Mir (17017734)

"…These reductions are attributed to decreased electricity requirements achieved via system synergies. …"

Comparison of Burr-Hole Craniostomy versus Twist-Drill Craniostomy Operations for Patients with Chronic Subdural Hematoma: A Systematic Review and Network Meta-Analysis حسب Mohammed Maan Al-Salihi (13105835)

"…We found that dBHC significantly decreased recurrence and reoperation rates compared with TDC (RR = 0.55, CI, 0.33–0.90 and RR = 0.48, CI, 0.24–0.94, respectively). …"

‘The newest vital sign among pregnant women attending women wellness and research Centre in Qatar: a cross-sectional study’ حسب Sarah Naja (9954737)

"…Furthermore, the insufficient level of health literacy was significantly associated with low educational background, decreased household income, and primigravida. However, uncontrolled glycaemia was the only significant predictor of inadequate health literacy through logistic regression. …"

Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS حسب Anna Halama (545988)

"…IS was lower in PCOS (p < 0.001) and was further decreased by the lipid infusion in both PCOS and controls. …"

Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine حسب Mariam Ahmed Amin Mohamed Elesnawy (21547187)

"…</p><p dir="ltr">Finally, silencing of <i>PKM2 </i>and<i> TUBA1B</i> in breast cancer cells increased DNA damage and decreased cancer cell survival, validating their role in genomic integrity and mimicking our previous observations following silencing of LDHC. …"

Part II.: Dissimilar friction stir welding of nickel titanium shape memory alloy to stainless steel – microstructure, mechanical and corrosion behavior حسب Parker West (17268946)

"…. % NaCl solution showed moderately inferior corrosion resistance of dissimilar weld, compared to individual base metals, as characterized by the surface film impedance and corrosion current density. The decreased corrosion resistance was attributed to inhomogeneous passive film formed across the weld due to zonal heterogeneities. …"

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy حسب Olfa Khalifa (10914452)

"…This reduction was confirmed by FTIR analysis, as the phospholipid band (C=O) at 1740 cm−1 in Ex-4 treated cells is significantly decreased compared to steatotic cells. The principal component analysis score plots for both the lipid and protein regions showed that the untreated and Ex-4-treated samples, while still separated, are clustered close to each other, far from the steatotic cells. …"

From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease حسب Ahmad Raza (18205961)

"…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …"

Photocatalytic deposition of cobalt atoms on two-dimensional nanocomposites as efficient visible-light-driven photocatalysts: Experimental study and intelligent modeling حسب Salar Heydari Shalmani (22589851)

"…Based on the DRS analysis, it was observed that the band gap energy of the synthesized samples was decreased compared to the one for pure TNs. The highest photocatalytic activity was obtained by the Co(76)/TNs/rGO(5) sample with 71.5% degradation of tetracycline (TC) (30 mg/L) under the visible light after 180 minutes. …"

Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study حسب Stefanos Volianitis (22155835)

"…Among the 14 amino acids measured, glutamate was released in the liver, while the uptake of free fatty acids decreased. During exercise at relatively low workloads, arterial lactate and ammonia levels were comparable to those seen in healthy subjects at higher workloads, while euglycemia was maintained due to sufficient hepatic glucose production. …"