Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... حسب Mohamed Yassin (4166515)

"…While some real-world studies have reported a decrease in VOCs and hospitalizations, the results are inconsistent and not conclusive. …"

Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response حسب Mingzhan Xue (3607649)

"…Human aortal endothelial cells and HMEC-1 microvascular endothelial cells were incubated in low and high glucose concentration to model blood glucose control, with increase or decrease of MG by silencing or increasing expression of glyoxalase 1 (Glo1), which metabolizes MG. …"

BRET-based biosensors for SARS-CoV-2 oligonucleotide detection حسب Asfia Sultana (19170880)

"…Following the assembly of the BioODs, we determined their kinetics response, affinity for variant-specific oligonucleotides, and specificity, and found them to be rapid and highly specific. Furthermore, the decrease in BRET efficiency of the BioODs in the presence of viral oligonucleotides can be detected as a change in color in cell phone camera images. …"

Application of Zn-ferrite towards thermochemical utilization of carbon dioxide: A thermodynamic investigation حسب Rahul R. Bhosale (6467102)

"…However, as the gas-to-gas heat recovery effectiveness increases to 0.9, this difference decreases to 11.8 kW. Because of this, the reduction in the solar-to-fuel energy conversion efficiency also drops to 0.6%. …"

Economic consequences of the covid 19 outbreak حسب Sidik, Hanan

"…The last part of the project is talking about the lockdown in UAE and the decrease of cases of covid and the people in UAE should always have the green pass to access the public sectors finally all the UAE citizens must be vaccinated in order to be safe .…"
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Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes حسب Abu Saleh Md Moin (6189512)

"…For example, overexpression of α cell specific transcription factor Arx or ablation of Pdx1 resulted in an increase of α cell numbers and a decrease in β cell numbers in rodents. The frequency of α-β double-positive cells was also prominent in human subjects with T2D. …"

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation حسب Abdelilah Arredouani (10914455)

"…Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …"

A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies حسب Y. Tong (18394389)

"…This structural modification also results in a significant decrease of the current. These findings can be useful in understanding the processes during the electron irradiation of molecular SAMs.…"

Correlating the rheological and magneto-optical properties of cobalt substituted magnetite ferrofluids (Co_xFe_1−xFe₂O₄) with theoretical... حسب Blessy Babukutty (17871482)

"…The optical measurement results demonstrate shift in band edge positions to blue region with decrease in particle size because of the quantum confinement effect. …"

Effects of organic enrichment on macrofauna community structure: an experimental approach حسب Rodrigo Riera (10476249)

"…AMBI and M-AMBI indices were calculated and a decrease of ecological status was observed in treatment 3x.…"

Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet حسب Neelam Iftikhar (14778400)

"…Higher doses of <i>Hibiscus rosa-sinensis</i> significantly decreased the levels of AST, ALT, AP, and SC in comparison with the HFSDC group. …"

Mechanisms behind the immediate effects of Roux-en-Y gastric bypass surgery on type 2 diabetes حسب Roland E Allen (19187023)

"…., the largest possible decrease in glucose predicted by the model is smaller than reported decreases, and the model predicts no decrease whatsoever in glucose ×insulin, in contrast to large observed decreases in homeostatic model assessment insulin resistance (HOMA-IR). …"

Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue حسب Ali Tiss (437068)

"…Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …"

Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study حسب Abduljaleel Abdullatif Zainel (18055382)

"…Higher levels of anger, depression, and general anxiety were prevalent among 1.3% (n=84), 3.9% (n=260), and 1.6% (n=104) of participants, respectively. The mean score for the emotional constructs anger and depression decreased with increased compliance with regulations (<i>P</i>=.04 and <i>P</i>=.11, respectively). …"

Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy حسب Abu Saleh Md Moin (6189512)

"…However, an increase in the percentage of clustered β-cells was found in pregnancy, with decreased frequency of other endocrine cells in clusters, suggesting a compensatory shift from other pancreatic endocrine cell types to β-cells as a mechanism to meet the increased insulin demands of pregnancy.…"

Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis حسب Osama Hussein (21301202)

"…In ACG patients, medication use decreased by 67.13% at 12 months and 51.58% at 24 months (<i>p</i> < 0.001 for both), while in OAG patients, the reduction was 45.52% at 12 months and 50.19% at 24 months (<i>p</i> < 0.001). …"

Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study حسب M. S Ajimsha (21250760)

"…The mean (SD) NIH-CPSI score at initial evaluation was 29.41 (8.3) and decreased to 9.14 (3.45) after the fifth visit. …"

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance حسب Zouhaier Farhani (22330693)

"…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…"

Ultra-low thermal conductivity in scheelite and A-deficient scheelite ceramics حسب Bsaibess, Eliane

"…BaMoO ceramic has shown a decrease in thermal conductivity from 0.8 W m K to 0.65 W m K from 400 K to 650 K. …"
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