PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"

Do near-bedtime usage of smartphones and problematic internet usage really impact sleep? A study based on objectively recorded usage data حسب Aftab Alam (5158601)

"…</p><h3> Results</h3><p dir="ltr">The multivariate linear regression showed that the increase in PIU (β = −0.231, p < 0.001) and smartphone usage two hours before sleep (β = −0.246, p < 0.001) led to decrease in sleep duration. Regarding sleep distraction, multivariate linear regression analysis revealed that two hours before sleep was a significant and positive predictor of sleep distraction (β = 0.197, p = 0.003), whereas PIU was not significant. …"

A decision support system for automating document retrieval and citation screening حسب Raymon van Dinter (10521952)

"…The proposed DSS is effective and can substantially decrease the document retrieval and citation screening steps' workload and error rate.…"

Coping strategies, optimism, and resilience factors associated with mental health outcomes among medical residents exposed to coronavirus disease 2019 in Qatar حسب Malek Smida (14777104)

"…Strategies promoting optimism, resilience, and approach coping styles can decrease the mental health burden of the pandemic on medical residents.…"

Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress حسب Munazza T. Fatima (17280679)

"…Importantly, SESN2 silencing, unlike thapsigargin, caused a dramatic decrease in protein expression and phosphorylation of Akt, a critical pro-survival hub and component of the AMPK/Akt/mTORC1 axis. …"

Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches حسب Roba Shady (22048043)

"…At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …"

Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization حسب Adrián Martín‐Segura (18615133)

"…In recent studies, we reported that the mild and gradual loss of cholesterol in the synaptic fraction of hippocampal neurons during aging leads to a decrease in synaptic plasticity evoked by glutamate receptor activation and also by receptor tyrosine kinase (RTK) signaling. …"

Thermodynamic Analysis of Gravity Assisted Solar-Powered Reverse Osmosis Unit for Greenhouses Situated in a Depleted Zone with Performance Evaluation and Improvements Using Nanoflu... حسب Yasser Mohamed Mohamed Taher Abdellatif (20741534)

"…The system utilises the Atlantic Ocean's hydrostatic pressure to decrease the reverse osmosis (RO) unit's power consumption. …"

Optimization of design and operation of solar assisted district cooling systems حسب Dana M. Alghool (18387132)

"…The sensitivity analysis shows that the chiller COP had the highest impact on the annual total system cost, where increasing COP by 20% of its initial value, will decrease the annual total system cost by 4.4%.</p><h2>Other Information</h2> <p> Published in: Energy Conversion and Management: X<br> License: <a href="http://creativecommons.org/licenses/by-nc-nd/4.0/" target="_blank">http://creativecommons.org/licenses/by-nc-nd/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.ecmx.2019.100028" target="_blank">https://dx.doi.org/10.1016/j.ecmx.2019.100028</a></p>…"

Shared Clean Mobility Operations for First-Mile and Last-Mile Public Transit Connections: A Case Study of Doha, Qatar حسب Afnan Fayez Eliyan (19517221)

"…Moreover, adding the carpooling option can significantly decrease the number of relocations operations at a minimal impact on the commuters’ trip performance.…"

Life cycle assessment of compressed air, vanadium redox flow battery, and molten salt systems for renewable energy storage حسب Manal AlShafi (14778373)

"…The global warming potentials of compressed air and vanadium redox flow battery decrease by 0.599 and 0.420 kg CO₂ eq,/kWh, respectively in case photovoltaic electricity is stored instead of grid electricity. …"

A new method for improving the solar photovoltaic unit efficiency through neem oil as coolant medium for high power applications—an experimental investigation حسب Karthikeyan Ganesan (269200)

"…Thus, the critical outcomes of the monocrystalline and polycrystalline PV panels are to decrease the panel temperature by 2.29% and 4.34%, respectively, and enhance the efficiency of the PV panels by 15.0% and 17.8%, respectively.…"

A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor حسب Anupriya M. Geethakumari (17052375)

"…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M^pro activity and a decrease in the inhibitory potential of GC376. The sensors developed here will find direct utility in studies related to drug discovery targeting the SARS-CoV-2 M^pro and functional genomics application to determine the effect of sequence variation in M^pro.…"

Role of family in supporting children with mental disorders in Qatar حسب Abdulnaser A. Fakhrou (16855155)

"…There are certain behaviors of family members that can increase or decrease stress for the person. The results suggest that the family plays an essential role in supporting and promoting the lives of people with mental disorders and recommending effective ways to cope with them.…"

Ambulatory general urgent clinic: an initiative at the time of COVID-19 pandemic حسب Abdullah Al-Hothi (18505290)

"…Our quality improvement study aimed to decrease the waiting time by 20%, from 21 days in January 2021 to 14 days in April 2021, to evaluate the newly established clinics for urgent referrals during the COVID-19 pandemic, and to assess the physicians’ satisfaction regarding these clinics.…"

High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry حسب E. Safamariyam (22330186)

"…Furthermore, the repeatability of the Ce_0.6 -MoS₂ sensor was assessed over 30 days, and a marginal decrease of 5% in response was observed from day 1 to day 30.…"

Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover حسب Naila Rabbani (291722)

"…Further research to decrease protein glycation in plants may lead to improved plant growth and assist the breeding of plant varieties resistant to environmental stress and senescence—including plants of commercial ornamental and crop cultivation value.…"

Evapotranspiration and water availability response to climate change in the Middle East and North Africa حسب Salah Basem Ajjur (14150967)

"…Outcomes reveal that the MENA region is indeed vulnerable to a surge in temperature, which can increase evapotranspiration losses and decrease water availability. Under the shared socioeconomic pathway (SSP2-4.5), the potential evapotranspiration (PET) has been projected to increase throughout the MENA region by up to 0.37 mm per year during the middle of the twenty-first century (2021–2050) and by up to 0.51 mm per year during the end of the twenty-first century (2071–2100). …"

An Exploration of Smoking Patterns Among People with Serious Mental Illness Attending an Outpatient Clinic in Qatar حسب Monica Zolezzi (10115698)

"…Many countries worldwide have observed a decrease in the prevalence of tobacco smoking; however, the smoking rates among people with SMI have declined much less than in those without mental illness. …"

Crumpled MXene nanosheets for sensing of ascorbic acid in food, biological fluids, and erythrocytes in-vitro microenvironment حسب Shabi Abbas Zaidi (4234354)

"…The sensor also demonstrated excellent reproducibility (~1 % RSD for five repetitive assays) and a shelf life of nearly one month with a negligible decrease in response. Furthermore, it lost only 10 % of its response for the next ten days. …"