Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments by Gunjan Dagar (9339276)

“…Despite success in blood cancers, CAR-T technology faces challenges in solid tumors, including lack of reliable tumor-associated antigens, hypoxic cores, immunosuppressive tumor environments, enhanced reactive oxygen species, and decreased T-cell infiltration. To overcome these challenges, current research aims to identify reliable tumor-associated antigens and develop cost-effective, tumor microenvironment-specific CAR-T cells. …”

An efficient claim management assurance system using EPC contract based on improved monarch butterfly optimization models by K. Mukilan (22224793)

“…Among the prevalent issues in this sector, cash flow problems frequently lead to decreased productivity and efficiency. To address these challenges, a claim management system is developed based on the Improved Monarch Butterfly Optimization Algorithm (IMBOA) and the principles of EPC. …”

Towards Industry 4.0 and Sustainable Manufacturing Applying Environmentally Friendly Machining of a Precipitation Hardened Stainless Steel Using Hot Turning Process by Mohammadjafar Hadad (17541345)

“…<p dir="ltr">This study aims to address the aforementioned challenges, solutions and implementation perspectives with regard to sustainable manufacturing. …”

Comparison of Burr-Hole Craniostomy versus Twist-Drill Craniostomy Operations for Patients with Chronic Subdural Hematoma: A Systematic Review and Network Meta-Analysis by Mohammed Maan Al-Salihi (13105835)

“…We found that dBHC significantly decreased recurrence and reoperation rates compared with TDC (RR = 0.55, CI, 0.33–0.90 and RR = 0.48, CI, 0.24–0.94, respectively). …”

Efficient Integration of Direct Air Capture With HVAC System by Yasser Mohamed Mohamed Taher Abdellatif (20741534)

“…Under humid conditions, replacing Lewatit with S-TEPA decreases thermal energy consumption from 425 kJ/molCO₂ to 325 kJ/molCO₂, and using S-PEI-L reduces it further to 275 kJ/molCO₂. …”

3D printing of circular materials: Comparative environmental analysis of materials and construction techniques by Shoukat Alim Khan (14778226)

“…For each such innovation, it is essential to ensure its environmental sustainability at an early stage of development. This study aims to assess the potential environmental advantages and disadvantages of newly developed construction and demolition waste (CDW)-based geopolymer materials for 3D printing of built-environment structures. …”

Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism by Tarek Fouda (18472476)

“…</p><h3>Results</h3><p dir="ltr">Patients within the PTH target range of 150 to 500pg/ml improved from 8% in June 2021 (on Cinacalcet) to 54% in June 2023 (on Etelcalcetide) (p=0 .0032) while patients with PTH above 1,000pg/ml decreased from 50% to 4% during the same period (p=0.00001) (Figure 2). …”

Financial Performance of Islamic and Conventional Banks in Oman: A Comparative Analysis by Zamzam Ismail Al Tubi (20741477)

“…The performance assessment of banks aims to ensure that the resources at their disposal are used effectively. …”

Ratings of Perceived Exertion Misclassify Intensities for Sedentary Older Adults During Graded Cycling Test: Effect of Supramaximal High-Intensity Interval Training by Georges Jabbour (754884)

“…For both groups, RPE decreases with SCE at 10 min following graded test correlated significantly to V˙O₂ (r = 0.61, p < 0.01). …”

Past and future climate effects on population structure and diversity of North Pacific surfgrasses by Ana I. Tavares (6942986)

“…<h3>Aim</h3><p dir="ltr">Understanding the impacts of past and future climate change on genetic diversity and structure is a current major research gap. …”

Essays on Digital Financial Inclusion and Financial Resilience for Sustainable Development in Sub-Saharan Africa by Jamila Abubakar (22653059)

“…A significant body of literature suggests the SSA’s middle class’s vulnerability to financial shocks, and our findings, indicating savings volatility and decreased savings accumulation due to financial shocks for the middle-income class groups, support these claims. …”

دور مكاتب الإصلاح والوساطة والتوفيق الأسري في الأردن في الحد من النزاعات الأسرية من وجهة نظر العاملين بها... by Al-Oqaili , Amneh Irshied

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Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Fiona B, Bennitt

“…We first estimated the mean fuel type-specific concentrations (in μg/m3) of fine particulate matter (PM2·5) pollution to which individuals using solid fuels for cooking were exposed, categorised by fuel type, location, year, age, and sex. …”
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Masked phenomenon: renal and cardiovascular complications; review and updates by Elmukhtar Habas (14777677)

“…The potential extension of the observed benefits of MP therapy, including a reduction in end-organ damage, remains questionable.</p><h3>Aim and methods</h3><p dir="ltr">This review aims to study the diagnostic methodology, epidemiology, pathophysiology, and significance of MP management in end-organs, especially the kidneys, cardiovascular system, and outcomes. …”

Occurrence and removal characteristics of phthalate esters from bottled drinking water using silver modified roasted date pits by Fedae A. Alhaddad (14152161)

“…<h2>Background</h2> <p>This paper aims to investigate the occurrence and removal characteristics of phthalate esters from bottled drinking water using silver modified roasted date pits. …”

Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient by Iman Hawari (12561958)

“…</p><h3>Aims</h3><p dir="ltr">Our main objective is to study the molecular mechanism of diabetes mellitus in LRBA-deficient patient and to investigate if LRBA has any role in insulin biosynthesis and secretion in β pancreatic cells.…”

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Alize J, Ferrari

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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

“…In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. …”
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Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …”
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 by Joan B Soriano (6458528)

“…However, when accounting for ageing and population growth, declines were observed in age-standardised prevalence (14·3% decrease), age-standardised death rates (42·6%), and age-standardised DALY rates (38·2%). …”