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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
منشور في 2023"…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …"
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Development of a thermodynamical approach for the prediction of the bulk modulus of spherical cubic silicon carbide <i>(β−SiC)</i> nanosolids
منشور في 2022"…The bulk modulus was found to decrease with respect to the size of the SiC NPs and was thus inversely proportional to their surface to volume ratio. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines
منشور في 2024"…However, their antibody‐dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. …"
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Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults
منشور في 2021"…Indeed, the survey results suggested (i) a change in the modality of acquiring food, consumers reduced the number of shopping trips and buying more on each trip to minimize store visits; (ii) a surge of stockpiling of non-perishable food items; (iii) a shift toward healthier diets; (iv) an increase in culinary capabilities; (v) a decrease of food waste. …"
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Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
منشور في 2024"…<p>Glucagon-like peptide-1 (GLP-1) agonists and GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) co-agonists are major treatment options for subjects with obesity and patients with type 2 diabetes mellitus (T2DM). …"
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The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017
منشور في 2020"…Globally, 38·2% (21·1–57·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24·5% (20·0–28·9) of the age-standardised DALYs were attributable to smoking in males. …"
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The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
منشور في 2020"…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …"
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Disrupted harvests: how Ukraine – Russia war influences global food systems – a systematic review
منشور في 2024"…Effects on food utilization are mainly seen in the decrease in diet quality and dietary diversity. The war also affected the stability dimension, mainly owing to the volatility of food prices and the uncertainty of the future food supply. …"
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…In addition, treated tumors showed significant dose-dependent decrease in mitotic activity index by 36.5% and 51% in comparison with the control group. …"
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A Comprehensive Assessment of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewables and Energy Storage Systems
منشور في 2022"…<p dir="ltr">E-mobility has become of great interest for many countries worldwide, where the main objective is to decrease the dependency on fossil fuel-based transportation means and reduce CO<sub>2</sub> emissions generated from the transportation sector. …"
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The Effect of Olanzapine, Tart Cherry, Fish Oil and High Fat in the Composition of the Gut Microbiome in Obese Mice
منشور في 2022"…</h4><h3>Result experiment 2 </h3><p dir="ltr">The alpha and beta diversity showed that no significant difference between the diets group. Regarding phyla, the gut microbiota for colon sample showed HFO in males, and HF in females induced a sufficient decrease in the relative abundance of Firmicutes in compared to other feeding types. …"
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
منشور في 2022"…The impact of biological processes depends on the process: calcification increases pCO2 while net primary production decreases pCO2. …"
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Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
منشور في 2024"…Fish fed with CURNPS at various levels exhibited remarkable increase in digestive enzymes (amylase and lipase), immune markers (immunoglobulin G (IgG), lysozyme and phagocytic indices), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)). A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …"
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Excess pCO<sub>2</sub> and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
منشور في 2022"…The impact of biological processes depends on the process: calcification increases pCO<sub>2</sub> while net primary production decreases pCO<sub>2</sub>. …"
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BRET-Based Biosensors for Nucleic Acid Detection and Impact of Molecular Crowding Monitoring
منشور في 2024"…While flexible biosensor exhibited a faster decrease in enzymatic activity compared to rigid biosensor. …"
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Non-linear relationship between real commodity price volatility and real effective exchange rate: The case of commodity-exporting countries
منشور في 2019"…Our results highlight that the relationship between real commodity price volatility and REER is non-linear and depends on the degree of financialization of the commodity market. …"
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Experimental investigation of double-pipe heat exchangers in air conditioning applications
منشور في 2018"…The collected data showed that the system efficiency depends more on the evaporator DIW flowrate than on the condenser DIW flowrate. …"
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
منشور في 2021"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"