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161
Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
منشور في 2019"…We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …"
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162
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
منشور في 2024"…Preserving the level of Factor H and CD59 in MSCs has significant clinical implication to increase their retention rate in hypoxic conditions and prolong their survival.…"
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163
Diabetic Sensorimotor Polyneuropathy Severity Classification Using Adaptive Neuro Fuzzy Inference System
منشور في 2021"…<p dir="ltr">Diabetic sensorimotor polyneuropathy (DSPN) is an early indicator for non-healing diabetic wounds and diabetic foot ulcers, which account for one of the most common complications of diabetes, leading to increased healthcare cost, decreased quality of life, infections, amputations, and death. …"
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164
The therapeutic potential of matcha tea: A critical review on human and animal studies
منشور في 2023"…Consuming matcha with a high-fat diet resulted in decreased weight gain velocity, food intake, improved serum glucose and lipid profile, reduced inflammatory cytokines and ameliorated oxidative stress. …"
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165
Simulation of the size-composition distribution of atmospheric nanoparticles over Europe
منشور في 2018"…The condensation of organics led to an increase (50 %–120 %) in the N100 concentration mainly in central and northern Europe, while the N10 concentration decreased by 10 %–30 %. …"
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166
SynergyGrids: blockchain-supported distributed microgrid energy trading
منشور في 2022"…<p>Growing intelligent cities is witnessing an increasing amount of local energy generation through renewable energy resources. …"
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167
Football-induced fatigue in hypoxia impairs repeated sprint ability and perceptual-cognitive skills
منشور في 2019"…Simulated matches in hypoxia revealed larger decreases, in RS and perceptual-cognitive skills, highlighting the need for optimal acclimatisation strategies, including physical and technical preparation, prior to playing at altitude.…"
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168
10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes
منشور في 2020"…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …"
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169
Investigating the Impact of Salinity Variations on Aerobic Granules and Activated Sludge Flocs: Emphasis on Performance Monitoring and Identification of Influential Salinity Compon...
منشور في 2022"…Consequent to the changes in the extracellular polymeric substances (EPS), there was an immediate decrease in sludge hydrophobicity resulting in a deterioration of settling, indicated by an increase in the sludge volume index (SVI), and loss of biomass for all the reactors. …"
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170
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
منشور في 2024"…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …"
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171
School children growth monitoring program in the state of Qatar: Observations from two survey rounds in 2016–17 and 2019–20
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">Overall, the proportion of overweight and obese category of students increased from 44% in 2016–17 to 49.3% in 2019–20 with a decrease in the proportion of students in normal BMI‐z‐score category (from 48.8% to 47.8%) and severe thinness and thinness category (from 7.3% to 3%) between two rounds of growth monitoring survey. …"
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172
The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic
منشور في 2023"…The COVID-19 pandemic led to a decrease in the use of HEDs by both faculty [38(64%)] and PGTs [42(60%)].…"
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173
Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
منشور في 2024"…STI positivity rates increased post-COVID-19 onset, although this increase was not statistically significant. …"
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174
The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global B...
منشور في 2019"…Although the overall colorectal cancer age-standardised death rate has been decreasing at the global level, the increasing age-standardised incidence rate in most countries poses a major public health challenge across the world. …"
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175
Which factor explains the life‐history of <i>Xanthium strumarium</i> L., an aggressive alien invasive plant species, along its altitudinal gradient?
منشور في 2022"…The X. strumarium exhibits late vegetative and reproductive phenology at higher altitudes, enabling them to occupy an empty niche and benefit from decreased competition for resource acquisition. The lower altitude plants show a higher growth rate (stem size increase, number of leaves, and leaf area) due to the higher nutrient availability. …"
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176
Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
منشور في 2024"…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …"
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177
Exploring urban growth–climate change–flood risk nexus in fast growing cities
منشور في 2022"…Surveying showed that, between 1984 and 2020, urban areas grew by 777%, and bare lands decreased by 54.7%. In addition, Doha witnessed various climatic changes with a notable increase in air temperature (+ 8.7%), a decrease in surface wind speed (− 19.5%), and a decrease in potential evapotranspiration losses (− 33.5%). …"
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178
Sleeping habits during COVID-19 induced confinement: A study from Jordan
منشور في 2021"…Majority of the participants (53–59%) reported an increase in most of the sleep parameters except a decrease (49.1%) in daytime sleep. …"
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179
Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection
منشور في 2024"…(iv) Agents moving in the right way are rewarded with an increase in their associated transition probability, while the agents going in the wrong direction are discouraged with a decrease in their associated transition probabilities; this promotes the establishment of an equilibrium state and leads to convergence. …"
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180
The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar
منشور في 2023"…</p> <h3>Conclusion</h3> <p>The results of this study suggest that in women with additional risk factors for FGR, the concurrent use of metformin significantly decreases the birthweight and increases the risk for LBW, SFD, PTB and admission to NICU. …"