Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1 حسب Bushra Memon (4792767)

"…These dissociated cells were subjected to an augmented duration of retinoid and fibroblast growth factor (FGF)10 signaling to induce higher PDX1 and NKX6.1 expression.</p><h3>Results</h3><p dir="ltr">Our optimized protocol dramatically increased the expression of NKX6.1, leading to an increase in the proportion of PDX1⁺/NKX6.1⁺ progenitors (~90%) in monolayer, higher than the previously published protocols, as well as upregulated key TFs controlling pancreatic development. …"

Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight حسب Muna Abed Alah (14779534)

"…Participants reported increased sitting/reclining time (1.94 h/day mean increase), screen times (2.05 h/day mean increase) with p < 0.001, and decreased exercise time (0.11 h/day mean reduction) with p < 0.001. …"

Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats حسب Rizk, Sandra

"…Selenium treatment of diabetic rats increased the pancreatic mRNA levels of GLP-1R, IRS-1, and preproinsulin. …"
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The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption حسب Sachin Wani (11704868)

Synthesis and polymerization of 1-(2-diallylaminoethyl) pyrimidines حسب Elaridi, Jomana

"…We report the preparation and characterization of three pyrimidine-based monomers, specifically: 1-(2-diallylaminoethyl)uracil, 1-(2-diallylaminoethyl)thymine and 1-(2-diallylaminoethyl)cytosine. …"
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Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins حسب Glazer, Evan

"…Immediate resection increased median survival from 42.3 to 53.5 months (p = 0.01). …"
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Increasing consultant-level staffing as a proportion of overall physician coverage improves emergency department length of stay targets حسب Dominic Jenkins (9983446)

"…</p><h3>Results</h3><p dir="ltr">Multivariate logistic regression adjusting for a number of operations factors (including total EP on-duty complement) identified an association between increasing n of on-duty Consultants and the likelihood of a shift’s meeting the 4-h ED LOS target (OR 1.27, 95% CI 1.20 to 1.34, p < .0001). …"

Correction to: Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation حسب Mahéva Vallet (18456729)

"…<p dir="ltr">Correction to: Targeted Inactivation of <i>Rin3</i> Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation <a href="https://doi.org/10.1007/s00223-021-00827-2" target="_blank">https://doi.org/10.1007/s00223-021-00827-2</a>, published online 16 March 2021.…"

Increased Fracture Risk After Bariatric Surgery: a Case-Controlled Study with a Long-Term Follow-Up حسب Omar Suhail Alsaed (14151861)

"…This study aimed to investigate whether bariatric surgery increases fracture risk.</p> <h2>Material and Methods</h2> <p>It was a case-controlled study. …"

Deletion of the Candida albicans PIR32 Results in Increased Virulence, Stress Response, and Upregulation of Cell Wall Chitin Deposition حسب Bahnan, Wael

"…As such, we measured cell wall chitin deposition and found a twofold increase in the mutant, possibly explaining the above-observed phenotypes.…"
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Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system حسب Frank Schmidt (207186)

Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response حسب Noura Al-Zeheimi (5177066)

"…Unlike NRP-1, circulating PlGF was significantly increased (<i>p</i> = 0.014) in patients with a pathological complete response (pCR). …"

Tryptophanyl-tRNA synthetase-1 (WARS-1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans حسب Mahmoud Izadi (12899508)

"…More recently, mutations in the tryptophanyl-tRNA synthetase 1 (WARS1) have been linked to various human diseases, from intellectual disability to various types of cancer. …"

Impacts of climate change on the global spread and habitat suitability of <i>Coxiella burnetii</i>: Future projections and public health implications حسب Abdallah Falah Mohammad Aldwekat (22457821)

"…<h3>Introduction</h3><p dir="ltr"><i><u>Coxiella burnetii</u></i><i><u>,</u></i> an intracellular zoonotic bacterium, affectsing various livestock and <u>wildlife</u> species and poses significant risks to human health. …"

Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells حسب Shebaby, Wassim N.

"…Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. …"
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Photoemission study of the electronic structure of LaFeAsO 1-xFx and LaFePO1-xFx حسب Malaeb, Walid

"…Also, in going from LaFeAsO1-xF x to LaFePO1-xFx, the near-EF intensity increases reflecting the weakening of electron correlation.…"
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Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase حسب Marta Cecchi (21363581)

Rodent-borne zoonoses in Qatar: A possible One-Health framework for the intervention of future epidemic حسب Md. Mazharul Islam (9082853)

"…<p>The increasing frequency of spillover of zoonotic pathogens from animals to humans in recent years highlights a need to develop a more comprehensive framework to investigate and prevent pathogens of animal origin, including rodents. …"

One Dimensional Seismic Site Response Analysis of United Arab Emirates حسب Eltayeb, Ahmed Mohamed Zaroug

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An optimization approach to increasing sustainability and enhancing resilience against environmental constraints in LNG supply chains: A Qatar case study حسب Sara Al-Haidous (18095368)