Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy حسب Jia-Zhen Wu (6844793)

"…We also found increased levels of LAMP-1 and LAMP-2A both <i>in vitro</i> and <i>in vivo</i>, along with decreased levels of α-synuclein. …"

Novel proteins implicated in lipid metabolism disorders حسب Nature Research (16552612)

"…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …"

Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. حسب Daher, Costantine F.

"…In the chronicstudy, only grapefruit significantly decreased plasma and VLDL TAG concentrations and relative VLDL particlesize with respect to other groups. …"
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Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Effects on in vivo ectopic bone formation were assessed by implanting hMSC mixed with hydroxyapatite-tricalcium phosphate granules subcutaneously in 8-week-old female nude mice, and the amount of bone formed was assessed using quantitative histology. Results. BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …"

Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection? حسب Abu Saleh Md Moin (6189512)

"…<h3>Background</h3><p dir="ltr">Women with polycystic ovary syndrome (PCOS) often have vitamin D deficiency, a known risk factor for severe COVID-19 disease. …"

Suppression of Rotating Stall by Throttle Rings Control in Vaneless Diffusers of Centrifugal Compressors حسب Mohammed, Dhafar

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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging حسب Dimassi, Hani

"…Children with white-matter abnormalities and increased tone had a greater frequency of increased reflexes and tended to have more signal abnormalities than the other groups. …"
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Coping mechanisms among Lebanese first-time college students حسب Doumit, Rita

"…Implications for Nursing Practice and Research: The results of this study will provide a better understanding of factors that are predictive of decreased well-being in Lebanese first-time college students and will be valuable in developing culturally sensitive intervention of stress and coping management program with a surveillance system and a systematic planning and evaluation procedure to respond to emerging and changing students’ needs at the Lebanese American University.…"
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Corner effects in CFRP-wrapped square columns حسب Tabbara, Mazen

"…An experimental investigation of the corner sharpness effect in square columns with carbon fibre-reinforced polymer (CFRP) wraps is presented using traditional compressive testing of short square columns as well as an innovative set-up that allows testing directly for the CFRP strength when wrapped around the corner of a flat slab. Both types of test confirmed the observation that the confinement efficiency decreases as the corner sharpness increases, owing to stress concentrations that cause localised failure of the CFRP.…"
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Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells حسب Ejlal Abu-El-Rub (5168183)

"…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"

Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells حسب Tawil, Mirna

"…In conclusion, DCOE induces selective apoptosis in AML cells, possibly through a MAPK-dependent mechanism.…"
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Efficiency of commercial banks in Lebanon حسب Djoundourian, Salpie

"…Using data from 1993 to 2002, we observe that the sector grew significantly in size as measured by assets, but the growth in assets was not accompanied by a similar growth in profits. Equity capital grew significantly over the period and the sector became safer. …"
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties حسب Ovidiu, Ciobanu

"…Tooth shade and enamel microhardness were evaluated using a digital spectrophotometer and a Vickers tester, respectively, at different time intervals after treatment. …"
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The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe حسب Ammari, Lora

"…This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …"
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties حسب Jelena Eric (21015107)

"…Tooth shade and enamel microhardness were evaluated using a digital spectrophotometer and a Vickers tester, respectively, at different time intervals after treatment. …"

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? حسب Abu Saleh Md Moin (6189512)

"…However, 4-hours post-hypoglycemia, sNRP1, VEGF and ADAM9 were elevated in T2D(p<0.05). SEMA3A was not different at baseline; at hypoglycemia, SEMA3A decreased in controls only. …"

Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy حسب Khoury, Reine

"…In old animals, damaged proteins accumulate in neurons since autophagy, a catabolic process responsible for organelle and protein degradation, decreases. …"
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The anti-cancer activity of 2 himachalene-6-OL extracted from daucus carota SSP. carota. (c2014) حسب Najm, Paul I.

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Can bitcoin’s volatility be tamed? حسب Ammous, Saifedean

"…As Bitcoin begins to attract attention as an investment asset, major questions remain about its volatility, whether that volatility can be reduced, and whether or not it could stand in the way of Bitcoin gaining a monetary role in society. This article explains Bitcoin’s volatility as a consequence of its completely inflexible and constantly decreasing supply growth, and describes why that is a design feature necessary for Bitcoin to operate successfully. …"
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Effect of Urtica dioica extract intake upon blood lipid profile in the rats حسب Daher, Costantine F.

"…Aqueous (150 mg/kg/day) and to a lesser extent petroleum ether (20 mg/kg/day) extract of Urtica dioica given for 30 days to rats fed with normal or high-fat diet, improved the blood lipid profile. …"
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