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301
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…The Safer Environment scenario had its largest decrease in sub-Saharan Africa (5·2% [3·5–6·8]), the Improved Behavioural and Metabolic Risks scenario in north Africa and the Middle East (23·2% [20·2–26·5]), and the Improved Nutrition and Vaccination scenario in sub-Saharan Africa (2·0% [–0·6 to 3·6]). …”
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302
Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
Published 2020“…The purified scFvs showed specific activity towards α-syn fibrils and oligomers in comparison to monomers and recognized intracellular inclusions in human post-mortem brain tissue of Lewy body disease cases, but not aged controls. In vitro studies indicated scFvs inhibit the seeding of α-syn aggregation in a time-dependent manner, decreased α-syn seed-induced toxicity in a cell model of PD, and reduced the production of insoluble α-syn phosphorylated at Ser-129 (pS129-α-syn). …”
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303
Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey
Published 2019“…Also, meeting recommended PA decreased with age [OR 0.92 (95% CI 0.90–0.94)] and body mass index [OR 0.93 (95% CI 0.91–0.95]; but increased per additional portion of fruit and vegetables taken [OR 1.19 (95% CI 1.12–1.25)] and with increase in well-being scale score [OR 1.05 (95% CI 1.03 to 1.06)]. …”
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Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
Published 2016“…DALY risk factors varied by age, with child and maternal malnutrition affecting the younger age groups (aged 28 days to 4 years), whereas high bodyweight and systolic blood pressure affected older people (aged 60–80 years). …”
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305
Acute intense fatigue does not modify the effect of EVA and TPU custom foot orthoses on running mechanics, running economy and perceived comfort
Published 2022“…Flight time shortened (P = 0.026), peak braking (P = 0.016) and push-off (P = 0.032) forces decreased and vertical stiffness increased (P = 0.014) from before to after the repeated-sprint exercise, independent of footwear condition. …”
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306
On the sampling and integration rates of process noise
Published 1995“…It is shown that the covariance of a sampled zero-mean exponentially-correlated process is independent of the sampling rate. …”
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307
A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…The results of the conducted computational experiments indicate that an increase in infrastructure investment through high speed chargers can significantly decrease the size of the necessary fleets. …”
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Effect of the location of broken wire wraps on the failure pressure of prestressed concrete cylinder pipes
Published 2015“…Two classes of 2.44 m embedded cylinder pipe (ECP) were modelled with 5, 35, 70, and 100 wire wrap breaks. The results show that broken wire wraps at the joint, and especially the spigot joint, decrease the overall strength of PCCP more so than those at the bell joint or in the barrel of the pipe. …”
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309
The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
Published 2022“…In this single-centre, cumulative, prospective, registry study, 321 hypogonadal men (mean age: 58.9 years) received testosterone undecanoate injections in 12-week intervals for up to 12 years. …”
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310
The immune landscape of solid pediatric tumors
Published 2022“…Clustering of immune traits revealed the same five principal modules previously described in adult tumors (TCGA). …”
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…As oncogenic transcriptomic downregulation is often driven by methylation of the promotor region, we explore the demethylation effect of 5-aza-2′-deoxycytidine (decitabine), on the SLFN11 gene. …”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Studies have shown that semaglutide reduced fat mass, particularly visceral fat, while preserving lean muscle mass, as the proportion relative to total body mass decreased by 3.5% and 2.0% for total and visceral fat mass, respectively, while it increased by 3.0% for lean body mass. …”
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314
Testing and Evaluation of a Smart Irrigation System Towards Smart Landscaping in UAE
Published 2019“…The outcomes of the use of SMS have shown better results in water conservation, 21%, and 26% decrease in water consumption for the months of September and October, respectively.…”
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315
Causes of Delay in Construction Projects in Oil and Gas Construction Industry
Published 2017“…With regard to design, the contractor’s need to decrease construction costs through a cheaper design was found to be a factor in design changes. …”
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316
Quantitative Compressibility Effects in Thermal Elastohydrodynamic Circular Contacts
Published 2015“…It is also observed that the relative errors on central film thicknesses induced by the use of the Dowson and Higginson relationship for compressibility increase with load and temperature and are very little affected by mean entrainment speed. Compressibility is shown to be a significant source of error in film-derived measurements of pressure-viscosity coefficients especially at high temperature. …”
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The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017
Published 2020“…Globally, 38·2% (21·1–57·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24·5% (20·0–28·9) of the age-standardised DALYs were attributable to smoking in males. …”
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Mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US: a recent analysis from the National Inpatient Sample
Published 2021“…In those patients, the mean (SD) age slightly decreased from 70 (13) years to 69 (13) years (p-trend < 0.001). …”