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821
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”
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822
Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO<sub>2</sub> intercooled and reheated cycles under design and off‐d...
Published 2022“…The ICC has the minimum levelized cost of electricity compared to the other cycles with 5.93 ¢/kWh at design conditions (dry‐cooling), 5.65 ¢/kWh at optimized conditions (wet‐cooling), and 7.2 ¢/kWh at minimum PD (21 MW). …”
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823
Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats
Published 2017“…Diabetic rats were injected intraperitoneally with 0.03 μg exendin-4/kg body weight/daily or treated with 5 ppm selenium in drinking water for a period of 4 weeks. …”
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824
Elastic Buckling Behavior of Functionally Graded Material Thin Skew Plates with Circular Openings
Published 2024“…Moreover, as the opening shifts from the plate’s edge closer to the center, the critical buckling load decreases by 26%. The critical buckling load is also dependent on the power index, as an increase in the power index from 0.2 to 5 reduced the buckling load by 1698 kN. …”
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825
Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
Published 2024“…However, agricultural areas decreased from 152.13 km<sup>2</sup> (18.5%) in 1980 to 140.38 km<sup>2</sup> (17%) in 2023, while barren lands decreased from 54.44 km<sup>2</sup> (6.6%) in 1980 to 34.71 km<sup>2</sup> (4.22%) in 2023. …”
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826
Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
Published 2019“…IS was lower in PCOS (p < 0.001) and was further decreased by the lipid infusion in both PCOS and controls. …”
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827
Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome
Published 2021“…Circulating levels of a panel of 18 clotting pathway proteins were determined by Slow Off-rate Modified Aptamer-scan plasma protein measurement. Cohorts were age matched, though PCOS had elevated body mass index (p < 0.001), insulin (p < 0.001) and C-reactive protein (CRP) (p < 0.0001). …”
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828
The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature
Published 2021“…<div><p>The level of immunoglobulins and cytokines changes with an ageing immune system. This review summarizes findings from studies that have examined the impact of acute and chronic exercise on immunoglobulins and cytokines in the elderly. …”
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829
IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
Published 2002“…Results: IL-1 increased ceramide accumulation in a time-dependent and concentration-dependent manner with a peak response at 4 h, with [IL-1] = 30 ng/ml. …”
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830
Mental Stress Assessment in the Workplace: A Review
Published 2024“…Workers with demanding jobs are at risk of experiencing mental stress, leading to decreased performance, mental illness, and disrupted sleep. …”
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831
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832
Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
Published 2023“…Therefore, the rapidity characteristic of a built environmental system to accept the change and uncertainty inherited from the past or generated over time is correlated to the system’s reflectivity quality. …”
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833
Receivers location privacy in avionic crowdsourced networks: Issues and countermeasures
Published 2021“…As a worst-case scenario, we demonstrate that, when a feasible number of receivers are deployed in the same area of a protected one, due to the nature of involved ADS-B data, standard time-based localization schemes can identify the location of any protected receiver. …”
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834
Evaluation of The Factors Affecting Microplastics and Nanoparticles in Plastic Water Supply Pipes
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835
Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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836
Advanced direct air capture of CO<sub>2</sub> using air conditioning systems: a life cycle assessment
Published 2025“…(ozone depletion), 8.889 × 10<sup>−5</sup> kg PM2.5 eq. (particulate matter formation), and 2.051 × 10<sup>−3</sup> m<sup>3</sup> (freshwater consumption). …”
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837
The promise of tirzepatide: A narrative review of metabolic benefits
Published 2025“…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. …”
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838
Chiropractic manipulations gone wrong
Published 2016“…Blood accumulates between the layers of the artery’s wall, obstructing blood flow and potentially forming clots. This, in turn, decreases the blood supply to the brain, causing stroke. …”
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839
Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H<sub>2</sub>S: DFT study
Published 2021“…Moreover, the adsorption distance (D) between H<sub>2</sub>S and Cu/Zn-ZGNR decreased remarkably to 2.23 Å and an S–Cu bond was generated. …”
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