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BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
Published 2024“…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …”
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Average Model-Based Feedforward and Feedback Control for PUC5 Inverter
Published 2020“…<p>This paper proposes new average model based control strategies for a 5-level Packed U-cell (PUC5) inverter in both standalone and grid-connected modes of operation. …”
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Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
Published 2018“…Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …”
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Crystallization properties of arsenic doped GST alloys
Published 2019“…<p dir="ltr">We present the enhanced properties observed in the phase change memory alloy Ge<sub>2</sub>Sb<sub>2</sub>Te<sub>5</sub> (GST) when doped with arsenic. …”
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Exercise-induced Citrate Enhances Associative Memory Formation by Modulating Histone Acetylation in a Sex-dependent manner
Published 2023“…Our results show that citrate enhances associative memory formation in male mice, but not female mice. …”
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
Published 2021“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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Fetoplacental transmission and placental response to SARS-CoV-2: Evidence from the literature
Published 2022“…The results indicated that SARS-CoV-2 induces placenta inflammation, and placenta susceptibility to SARS-CoV-2 decreases across the pregnancy window. …”
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
Published 2023“…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…”
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Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy
Published 2022“…In old animals, damaged proteins accumulate in neurons since autophagy, a catabolic process responsible for organelle and protein degradation, decreases. Physical exercise is a known lifestyle factor that promotes learning and memory formation in the hippocampus. …”
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Timing driven genetic algorithm for standard-cell placement
Published 1995“…In this paper we present a timing-driven placer for standard-cell IC design. …”
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Part II.: Dissimilar friction stir welding of nickel titanium shape memory alloy to stainless steel – microstructure, mechanical and corrosion behavior
Published 2021“…The decreased corrosion resistance was attributed to inhomogeneous passive film formed across the weld due to zonal heterogeneities. …”
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Examining time-to-transport decisions in Emergency Medical Services
Published 2024“…</p><h3>Results</h3><p dir="ltr">Figure 1 indicates the transport probabilities as inferred from the Cox regression. As the time spent on scene increases (due to various reasons, among them: spending more time providing clinical treatment and health education because the patient decided not to go to the hospital, or the crew spending more time convincing the patient to go to the hospital by explaining the potential complications of their condition and the potential outcomes of a refusal to go to hospital), the probability of transporting the patient decreases. …”
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A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor
Published 2022“…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M<sup>pro</sup> activity and a decrease in the inhibitory potential of GC376. The sensors developed here will find direct utility in studies related to drug discovery targeting the SARS-CoV-2 M<sup>pro</sup> and functional genomics application to determine the effect of sequence variation in M<sup>pro</sup>.…”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis
Published 2020“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.…”
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Published 2019“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”
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Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains
Published 1991“…We studied 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in 5 strains of rats by assessing mortality and brain monoamine changes after MPTP injections into the internal carotid artery. …”
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Coping mechanisms among Lebanese first-time college students
Published 2012“…As scores on resilience, social support and being male increased, the well-being of Lebanese first-time College students also increased. As the usage of withdrawal coping strategies, being exposed to stress related to self and uncertainty increased, the well-being of Lebanese first-time college students decreased. …”
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Dielectric Properties of Y3Fe5O12 (YIG) Prepared at Different Molarities of NaOH
Published 2020“…In this study, Yttrium Iron Garnet (Y3Fe5O12) (YIG) powders were synthesized via co-precipitation method, followed by calcining the precipitates at 1100˚C. …”
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