Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…Conversely, the peptide inhibitor restores endolysosomal function and thereby decreases α-synuclein levels in multiple models, including female and male human cells harboring disease-causing α-synuclein mutations. …”

Shear Strength Behaviors of Tire Shred-Dune Sand Admixtures by Elmootassem, Ruba A.

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Meta-Heuristic Algorithm-Tuned Neural Network for Breast Cancer Diagnosis Using Ultrasound Images by Ahila A (18394806)

“…Early diagnosis is the only way to increase the treatment options which then decreases the death rate and increases the chance of survival in patients. …”

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults by Nowell H, Phelps

“…From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. …”
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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study by Rajesh, Sharma

“…Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …”
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Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1 by Natalie C Galles (9715361)

“…The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56·8 million (52·6–60·9) to 14·5 million (13·4–15·9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. …”

PP245-SUN: Outstanding abstract by Bassil, M.

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Effect of climate change on the annual energy consumption of a single family house in British Columbia by Mutasim Baba, Fuad

“…The simulation results show that for both bylaw and PH cases, heating energy consumption will be reduced while cooling energy consumption will be increased, as a result for bylaw case, the energy consumption will be decreased for four climate zones, while for PH case, the energy consumption will be increased for zone 4 & 5 and decreased for zone 6 & 7. …”
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Microstructure and Compressive Behavior of Al–Y₂O₃ Nanocomposites Prepared by Microwave-Assisted Mechanical Alloying by Manohar Reddy Mattli (18147568)

“…The mechanical properties of the Al–Y₂O₃ nanocomposites increased as the addition of yttria reached to 1.5 vol. % and thereafter decreased. The microhardness first increased from 38 Hv to 81 Hv, and then decreased to 74 ± 4 Hv for 1.5 vol. % yttria. …”

Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment by Farhat, Peter

“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
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Chemopreventive effects of wild carrot oil against 7,12-dimethyl benz(a)anthracene-induced squamous cell carcinoma in mice by Abu Zeinab, Rami

“…Topical 50% treatment inhibited tumor incidence and yield by 30 and 83%, respectively, whereas the 5% treatment inhibited tumor yield by 36%. Tumor volume was decreased by 99, 91, and 70% following topical treatments with 100, 50, and 5% oil, respectively. …”
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

“…Results rs4769874 (ALOX5AP), rs854560 (PON1), and rs4646903 (CYP1A1 MspI polymorphism) are significantly associated with an increased risk of CAD with respective odds ratios of 1.53703, 1.67710, and 1.35520; the genetic variant rs9579646 (ALOX5AP) is significantly associated with a decreased risk of CAD (OR 0.76163). …”
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Determinants of dividend payout ratio by Elgammal, Walid

“…The study focuses only on the cement and construction industry within the MENA region in an attempt to isolate any incoherent behavior. …”
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Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... by Jaimie D Steinmetz (18015919)

“…Age-standardised prevalence of avoidable blindness decreased by −15·4% [–16·8 to −14·3], while avoidable MSVI showed no change (0·5% [–0·8 to 1·6]). …”

Protein and pH-dependent Binding of Nascent Pectin and Glucuronarabinoxylan to Xylogucan in Pea by Rizk, Sandra

“…The binding was maximum at low pH (3–4), and decreased to almost zero at pH 6. The binding was probably non-covalent and reached saturation within 5 min. …”
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Basin of Attraction through Invariant Curves and Dominant Functions by Al-Sharawi, Ziyad

“…For 0 < ℎ < 1, we study the stability of the equilibrium solutions and find an invariant region where solutions are attracted to the stable equilibrium. …”
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Monitoring polycyclic aromatic hydrocarbons in the Northeast Aegean Sea using Posidonia oceanica seagrass and synthetic passive samplers by Pavlopoulos, Kosmas

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Effect of climate change on the energy performance and thermal comfort of high-rise residential buildings in cold climates by Mutasim Baba, Fuad

“…As a result, for the bylaw case, the total energy consumption would be decreased for two climate zones, while for PH case, the total energy consumption would be increased for zone 4 and decreased for zone 7. …”
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Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System by Bair, Scott

“…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…”
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... by Haidong, Wang

“…Under-5 deaths declined from 9·6 million (9·1–10·3) in 2000 to 5·0 million (4·3–6·0) in 2019. …”
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