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621
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
منشور في 2024"…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation‐contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l‐type Ca<sup>2+</sup> (Ca<sub>v</sub>1.2), sodium (NaV1.5) and potassium (KV7.1) channels. …"
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622
Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells
منشور في 2003"…Overexpression of hAT1R and hAT1R GFP decreased both basal cytosolic and nuclear Ca2+. In normal hVSMCs and low hAT1R GFP overexpressing hVSMCs, Ang II (10 15 to 10 4 M) induced a dose-dependent sustained increase of [Ca]c and [Ca]n with an EC50 near 5 × 10 11 and 5 × 10 9 M, respectively. …"
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623
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
منشور في 2021"…Liquid (bounce fraction; BF < 0.2) at RH > 80 % and nonliquid behaviour (BF > 0.8) at RH < 30 % were observed, with a liquid-to-nonliquid transition with decreasing RH between 30 % and 80 %. This RH-dependent phase behaviour (RH<sub>BF=0.2, 0.5, 0.8</sub>) increased towards a maximum, with an increasing organic–inorganic mass ratio (MR<sub>org</sub><sub>/inorg</sub>) during SOA formation evolution in all investigated VOC systems. …"
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624
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
منشور في 2014"…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …"
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625
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
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626
Tailoring the deposition of MoSe<sub>2</sub> on TiO<sub>2</sub> nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting
منشور في 2023"…Compared to pure TiO<sub>2</sub> NRs, the heterojunction nanostructured assembly displayed excellent spectral and photoelectrochemical properties, including more surface oxygen vacancies, enhanced visible-light absorption, higher photocurrent response, and decreased charge transfer resistance. In particular, the sample synthesized by sputtering of MoSe<sub>2</sub> for 90 s, i.e., MoSe<sub>2</sub>@TiO<sub>2</sub>-90 s, depicted the highest current density (1.86 mA cm<sup>−2</sup> at 0.5 V vs. …"
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627
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628
Solar Technology and District Cooling System in a Hot Climate Regions: Optimal Configuration and Technology Selection
منشور في 2022"…The PVT-DCS configuration has the lowest operation cost and the highest environmental performance by decreasing the global warming potential by 89.5%. The T-DCS configuration becomes economically competitive only at high electricity tariffs.…"
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629
Enhanced thermoelectric properties of Bi<sub>2</sub>Te<sub>2.55</sub>Se<sub>0.45</sub> nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable...
منشور في 2025"…However, adding higher amounts (0.1, 0.5, and 1) decreased the electrical and thermal conductivities due to the dominant effect of bulky precipitates in increasing the scattering of charge carriers and phonons. …"
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630
An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH<sub>4</sub>-CO<sub>2</sub>-H<sub>2</sub>S
منشور في 2021"…The model predictions for the solidification points of 5 different mixtures were within the acceptable error when compared to the experimental data available in the literature. …"
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631
Past and future climate effects on population structure and diversity of North Pacific surfgrasses
منشور في 2024"…Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …"
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632
Therapeutic targeting of the TPX2/TTK network in colorectal cancer
منشور في 2023"…The growth potential of CRC cells under 3-dimensional (3D) conditions was assessed using Matrigel. STRING database (v11.5) and Ingenuity Pathway Analysis (IPA) tool were used for network and pathway analyses. …"
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633
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…</p><h2>Other Information</h2><p dir="ltr">Published in: BMC Health Services Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12913-022-08981-5" target="_blank">https://dx.doi.org/10.1186/s12913-022-08981-5</a></p>…"
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634
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635
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636
Acute pain management and assessment
منشور في 2012احصل على النص الكامل
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637
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638
Functionalization of reverse osmosis membrane with graphene oxide to reduce both membrane scaling and biofouling
منشور في 2020"…After functionalization, the membrane surface properties were improved as the water contact angle was reduced from 41.7 ± 4.5⁰ to 26.9 ± 0.9⁰ demonstrating improvement in hydrophilic properties besides decreasing membrane surface roughness. …"
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639
Marine Bacterial Community Structures of Selected Coastal Seawater and Sediment Sites in Qatar
منشور في 2023"…<i>Alphaproteobacteria</i> (33.87%, 16.82%),<i> Flavobacteria</i> (30.68%, 5.84%), and Gammaproteobacteria (20.35%, 12.45%) were abundant at the species level in both seawater and sediment, while <i>Clostridia</i> (13.72%) was abundant in sediment only. …"
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640
Synthesis of lithium manganese oxide nanocomposites using microwave‐assisted chemical precipitation technique and their performance evaluation in lithium‐ion batteries
منشور في 2023"…The LMO-CNTs and LMO-GNPs have an excellent rate capability of 124 and 127 mAhg<sup>−1</sup> at 0.1C, sustained at 115.6 and 118.5 mAhg<sup>−1</sup> at 10C, respectively. Cycling efficiency is also improved, with LMO-CNTs and LMO-GNPs having an initial capacity of 124 and 127 mAhg<sup>−1</sup> decreasing to 112 and 114 mAhg<sup>−1</sup>, respectively, after 50 cycles. …"