-
721
Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th...
Published 2020“…Age-standardised prevalence of avoidable blindness decreased by −15·4% [–16·8 to −14·3], while avoidable MSVI showed no change (0·5% [–0·8 to 1·6]). …”
-
722
Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1
Published 2021“…The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56·8 million (52·6–60·9) to 14·5 million (13·4–15·9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. …”
-
723
-
724
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …”
Get full text
Get full text
Get full text
conferenceObject -
725
Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity
Published 2021“…A hyperinsulinemic clamp was performed and normoglycemia induced in T2D [4.5 ± 0.07 mmol/L (81 ± 1.2 mg/dl)] for 1-h, following which blood glucose was decreased to ≤2.0 mmol/L (36 mg/dl). …”
-
726
-
727
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Published 2019“…Human aortal endothelial cells (HAECs) were incubated in high glucose concentration (20 mM versus 5 mM control) in vitro for 3–6 days. Flux of glucose metabolism, MG formation and glycation and changes in cytosolic protein abundances, MG modification and proteotoxic responses were assessed. …”
-
728
Machine Learning-Based Management of Electric Vehicles Charging: Towards Highly-Dispersed Fast Chargers
Published 2020“…<p dir="ltr">Coordinated charging of electric vehicles (EVs) improves the overall efficiency of the power grid as it avoids distribution system overloads, increases power quality, and decreases voltage fluctuations. Moreover, the coordinated charging supports flattening the load profile. …”
-
729
The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women
Published 2018“…</p><h3>Materials and Methods</h3><p dir="ltr"> We examined the effect of soy isoflavones on reverse tri-iodothyronine (or 3,3′,5′-tri-iodothyronine; rT<sub>3</sub>) in two studies comprising 400 patients: 200 men (study 1; 3 months) and 200 post-menopausal women (study 2; 6 months) who were randomized to consume 15 g soy protein with 66 mg of isoflavones (SPI) daily, or 15 g soy protein alone without isoflavones (SP) daily.…”
-
730
An ensemble-based machine learning model for predicting type 2 diabetes and its effect on bone health
Published 2024“…We believe Dapagliflozin prescriptions in Qatar were associated with decreased Gamma Glutamyltransferase and Aspartate Aminotransferase enzyme levels, confirming prior research. …”
-
731
Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype...
Published 2023“…Among the 835 proteins, two showed differential responsiveness to insulin; ATP5F1 protein was decreased, and MYLK2 was higher in the LIS group compared with that in the HIS group. …”
-
732
-
733
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…Using this approach, a total of 47 proteins showed at least 1.5 fold change between lean and obese subjects. …”
-
734
The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
Published 2019“…</p><h3>Conclusions</h3><p dir="ltr">This post-hoc analysis revealed that 12 weeks of atorvastatin treatment significantly decreased the markers of adipose tissue dysfunction and inflammation, namely ASP, IL-6 and MCP-1 in obese women with PCOS. …”
-
735
Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
Published 2019“…</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">CPHN cell frequency decreased 84% (islets) and 42% (clusters) from fetal to infant life. …”