A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells by Abou-Ghazal, Mohamed K.

“…Results WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against melanoma cell line A375, B16 and B16EGFRvIII, respectively. …”
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The effect of doping MoSe₂ by clusters of noble metals on its adsorption for NH₃ by Ahmad I. Ayesh (10188469)

“…Herein, the magnitude of adsorption energy increases and the adsorption distance deceases for NH₃ gas. …”

Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase by Marta Cecchi (21363581)

“…<p dir="ltr">In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. …”

The impact of nozzle diameter and printing speed on geopolymer-based 3D-Printed concrete structures: Numerical modeling and experimental validation by Shoukat Alim Khan (14778226)

“…<p dir="ltr">3D Concrete Printing (3DCP) is a promising technology with significant advantages for the construction industry, encompassing reduced labor costs, diminished carbon dioxide emissions, enhanced time efficiency, improved user convenience, and design flexibility. …”

A Financial Statement Analysis on Three Major Construction Companies in the UAE (Arabtec Holding PJSC, Drake & Scull PJSC and Emaar Properties PJSC) by AlEid, AlJazzy Bint Mohamed

“…Financial statement analysis has been carried out with respect to three construction companies that are operating in UAE that are, Arabtec Holding PSJC, Drake & Scull PSJC and Emaar Properties PSJC. …”
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Three-dimensional evaluation of pulp chamber volume and dimensions across skeletal and dental malocclusions using CBCT: a retrospective cross-sectional study by Raidan Ba-Hattab (17773230)

“…Posterior crossbite correlates with increased molar PCV.</p><h3 dir="ltr">Clinical relevance</h3><p dir="ltr">Skeletal and occlusal variation should be considered during endodontic access planning and when interpreting radiographs to avoid misjudging pulp size in patients with atypical skeletal and dental relationships.…”

Reinforcement R-learning model for time scheduling of on-demand fog placement by Farhat, Peter

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The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling by Muneera Vakayil (12037693)

“…<p dir="ltr">The E3 ubiquitin-ligase UHRF1 is an epigenetic regulator coordinating DNA methylation and histone modifications. …”

Development and Testing of Novel Drilling Fluids Using Fe2O3 and SiO2 Nanoparticles for Enhanced Drilling Operations by Vryzas, Zisis

“…The filtration efficiency was reduced with the increase of the concentration of Fe2O3 nanoparticles which was confirmed by CT scan measurements. …”
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Milk Other Than Breast Milk and the Development of Asthma in Children 3 Years of Age. A Birth Cohort Study (2006–2011) by Asmaa El-Heneidy (8844911)

“…This study indicates that the introduction of MOTBM in the first six months of life is a risk factor for asthma incidence among 3-year old children. This result is important in explaining the benefits of breastfeeding as part of public health interventions to encourage mothers to increase breastfeeding initiation and duration, and avoid the introduction of MOTBM in the first six months after childbirth.…”

Over‐expression of the p110β but not p110α isoform of PI 3‐kinase inhibits motility in breast cancer cells by Yip, Shu-Chin

“…Phosphoinositide 3-kinase (PI 3-kinase) activity is required for growth factor-induced cytoskeletal regulation and cell migration. …”
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How circular economy can reduce scope 3 carbon footprints: Lessons learned from FIFA world cup Qatar 2022 by Hana Yousef, Al Sholi

“…However, such events also leave significant negative impacts on the environment such as an increase in greenhouse gas (GHG) emissions in the host and neighboring countries. …”
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Petrophilic, Fe(III) Reducing Exoelectrogen Citrobacter sp. KVM11, Isolated From Hydrocarbon Fed Microbial Electrochemical Remediation Systems by Krishnaveni Venkidusamy (4950109)

“…The electrochemical activities of the strain KVM11 were characterized in a single chamber fuel cell and three electrode electrochemical cells. The inoculation of strain KVM11 amended with acetate and citrate as the sole carbon and energy sources has resulted in an increase in anodic currents (maximum current density) of 212 ± 3 and 359 ± mA/m² with respective coulombic efficiencies of 19.5 and 34.9% in a single chamber fuel cells. …”

Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment by Farhat, Peter

“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
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Subclavian pseudoaneurysm presenting as partially obstructed airway by Muhammad J., Khan

“…Managing the patient's airway posed significant challenges, including the risk of failed intubation, bleeding, and inability to oxygenate the patient.The case highlights the increasing importance of 3-Dimensional reconstruction computerized tomography in accurately diagnosing tracheal narrowing and compression. …”
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Additive Manufacturing of Polymer/Mg-Based Composites for Porous Tissue Scaffolds by Fawad Ali (2154529)

“…<div><p>Due to their commercial availability, superior processability, and biocompatibility, polymers are frequently used to build three-dimensional (3D) porous scaffolds. The main issues limiting the widespread clinical use of monophasic polymer scaffolds in the bone healing process are their inadequate mechanical strength and inappropriate biodegradation. …”

Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways by Daaboul, Hamid E.

“…Western blot analysis revealed a significant decrease in p-Erk, p-Akt, pro-caspase-3 and Bcl-2 and an increase in p53, p21, Bax and PARP proteins. …”
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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model by Sahar Isa Da’as (18288880)

“…Although cardiac contractility was similar to the wild-type control, the ejection fraction was significantly increased in the mypbc3 mutants. At later stages of larval development, the mutants demonstrated an early cardiac phenotype of myocardium remodeling, concurrent cardiomyocyte hyperplasia, and increased ejection fraction as critical processes in HCM initiation to counteract the increased ventricular myocardial wall stress. …”

MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles by Micol Marchetti (18623410)

“…Exposure to hypoxia increased miR-24-3p in ECs but not in pericytes. Transfection with a miR-24-3p precursor (pre-miR-24-3p) increased miR-24-3p expression in ECs, reducing the cell survival, proliferation, and angiogenic capacity. …”

Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia by Shilpa Kuttikrishnan (3520079)

“…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. Curcumin treatment increased the ratio of Bax/Bcl-2 and resulted in a leaky mitochondrial membrane that led to the discharge of cytochrome c from the mitochondria to the cytoplasm, the activation of caspase 3 and the cleavage of PARP. …”