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801
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802
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”
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803
Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
Published 2024“…However, agricultural areas decreased from 152.13 km<sup>2</sup> (18.5%) in 1980 to 140.38 km<sup>2</sup> (17%) in 2023, while barren lands decreased from 54.44 km<sup>2</sup> (6.6%) in 1980 to 34.71 km<sup>2</sup> (4.22%) in 2023. …”
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804
Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO<sub>2</sub> intercooled and reheated cycles under design and off‐d...
Published 2022“…The ICC has the minimum levelized cost of electricity compared to the other cycles with 5.93 ¢/kWh at design conditions (dry‐cooling), 5.65 ¢/kWh at optimized conditions (wet‐cooling), and 7.2 ¢/kWh at minimum PD (21 MW). …”
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805
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…Further, chronic Gln accumulation and decreased proteolysis were found to induce the early onset of an age‐related muscle phenotype.…”
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806
Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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807
Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
Published 2023“…Patient satisfaction from the provided interventions/services was determined by means of an overall rating. The correlation between practiced roles and patient satisfaction with received interventions/services was determined.…”
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808
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
Published 2022“…Moreover, the cutaneous wound tissues treated with PDL 20, MM, and QM exhibited significantly higher hydroxyproline content than the negative control group, which means a high collagen biosynthesis in wound tissues. …”
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809
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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810
Advanced direct air capture of CO<sub>2</sub> using air conditioning systems: a life cycle assessment
Published 2025“…(ozone depletion), 8.889 × 10<sup>−5</sup> kg PM2.5 eq. (particulate matter formation), and 2.051 × 10<sup>−3</sup> m<sup>3</sup> (freshwater consumption). …”
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811
The promise of tirzepatide: A narrative review of metabolic benefits
Published 2025“…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. …”
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812
Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy
Published 2023“…</p> <h2>Results</h2> <p>The frequency of clustered β-cells was increased in pregnant compared to non-pregnant subjects (46.6 ± 5.0 vs. 31.8 ± 5.0% clustered β-cells of total clustered endocrine cells, pregnant vs. non-pregnant, <em>p</em> < .05). …”
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813
Chiropractic manipulations gone wrong
Published 2016“…Blood accumulates between the layers of the artery’s wall, obstructing blood flow and potentially forming clots. This, in turn, decreases the blood supply to the brain, causing stroke. …”
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814
Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H<sub>2</sub>S: DFT study
Published 2021“…Moreover, the adsorption distance (D) between H<sub>2</sub>S and Cu/Zn-ZGNR decreased remarkably to 2.23 Å and an S–Cu bond was generated. …”
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815
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816
Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
Published 2023“…Multivariate logistic regression analyses showed that the likelihood of all-cause mortality was significantly higher in overweight and all categories of obese patients compared to underweight patients: overweight (OR: 5.3, 95% CI: 2.3–11.9, p< 0.001); obese class 1 (OR: 5.4, 95% CI: 2.3 – 12.2, p< 0.001); obese class 2 (OR: 6.5, 95% CI: 2.7 – 15.6, p< 0.001); and obese class 3 (OR: 3.7, 95% CI: 1.6 – 8.7, p = 0.003).…”
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817
Rhegmatogenous retinal detachments associated to Stickler syndrome in a tertiary eye care center in Saudi Arabia
Published 2016“…Visual acuity improved in 54% of eyes and decreased in 5%. Statistically significant associations were present for eyes with final visual acuity ≥20/200, and total retinal detachment (P<0.001); preoperative cataract (P=0.023); and proliferative vitreoretinopathy (P<0.001). …”
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818
α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain
Published 2022“…In the hippocampus, aKG increases BDNF levels possibly through the PGC1a-BDNF pathway. In the NAc, aKG decreases BDNF levels possibly through the FNDC5-BDNF pathway.…”
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masterThesis -
819
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820
