Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy حسب Jia-Zhen Wu (6844793)

"…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …"

Inappropriate Medication Use in Elderly Lebanese Outpatients حسب Saab, Yolande B.

"…With increasing availability of newer and more appropriate medications, use of potentially inappropriate drugs may decrease. Pharmacists have a major role to play in counselling patients about the importance of appropriate drug use.…"
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Muhanad Alhujaily (11630107)

"…MG activated the intrinsic pathway of apoptosis, with decrease of mitochondrial and spliceosomal proteins. …"

Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study حسب Shubham Chauhan (21334742)

"…</p><h3>Results</h3><p dir="ltr">A slight decrease in incidence rates from 80.57 to 79 per 100,000 was observed, alongside a significant increase in mortality rates from 14.11 to 17.2 per 100,000. …"

The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study حسب Almu'atasim Khamees (11875640)

"…While those who had a decrease in their smoking level experienced a somehow healthier lifestyle regarding nutrition and other aspects.…"

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis حسب Fateen Ata (12217764)

"…Results from this study with a diverse population may be valuable for physicians and healthcare systems to decrease the diabetes-related healthcare burden in DKA patients.…"

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. A decreased risk of lymph node metastasis was associated with the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-C</b> allele, particularly in <b>rs1294255-GC</b> (OR = 0.47; <i>P</i> = 0.001). …"

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m²) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …"

The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar حسب Komal Rafique (17075074)

"…</p> <h3>Conclusion</h3> <p>The results of this study suggest that in women with additional risk factors for FGR, the concurrent use of metformin significantly decreases the birthweight and increases the risk for LBW, SFD, PTB and admission to NICU. …"

SYSTEM DYNAMICS APPROACH FOR WHOLE LIFE CYCLE COST MODELLING OF RESIDENTIAL BUILDING PROJECTS IN UNITED ARAB EMIRATES حسب Sadek, Ahmed

"…Cost impact is following an increasing S-Curve behaviour during CAPEX time and risk impact is following a decreasing S-Curve behaviour during CAPEX lifetime. …"
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Synergetic effects of dodecylamine-functionalized graphene oxide nanoparticles on antifouling and antibacterial properties of polysulfone ultrafiltration membranes حسب Abedalkader Alkhouzaam (15842647)

"…All membranes were characterized in terms of chemical structure, morphology, hydrophilicity, porosity and mean pore size. Cross-section SEM images showed the distribution of GO and rGO-DDA between the pores and on the polymer walls. …"

Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM) حسب Mohammad Hadi Ahmad (17632248)

"…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …"

Using Data Mining and Text Mining Techniques in Predicting the Price of Real Estate Properties in Dubai حسب Khashan, Deena Younis Abo

"…It is found that the results of linear regression prediction have been improved significantly after adding text mining to the experiments. The root mean squared errors RMSEs for all data subsets have decreased leading to enhancing the accuracy of prediction. …"
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Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer حسب Adviti Naik (673163)

"…In this study, we investigated the effects of tumor LDHC expression on immune responses.</p><h3>Methods</h3><p dir="ltr">TIMER AND TIDE deconvolution methods were used to investigate the relationship between tumor <i>LDHC</i> expression, immune cell infiltration and T cell dysfunction. …"

Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

"…These findings contribute to the growing understanding of nanoparticle toxicity profile and underscore the need for further research to ensure the safe application of nanoparticles in biomedical and other fields.…"

Novel proteins implicated in lipid metabolism disorders حسب Nature Research (16552612)

"…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …"

Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress حسب Jing Ma (24574)

"…Our results illustrated that the increasing levels of Cd in the sand, significantly (P < 0.05) decreased shoot length, root length, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, germination percentage, germination index, mean germination time, time to 50% germination, chlorophyll a, chlorophyll b, total chlorophyll and carotenoid contents in all genotypes of B. oleracea. …"

Did the periodic intensification of routine immunisation strategy (Intensified mission Indradhanush) reduce the demand for pediatric antibiotic formulations in India? حسب Habib Hasan Farooqui (7861166)

"…Interestingly, Trimethoprim sales increased by 17.1% in the first month but decreased by 0.4% per month (IRR 0.959, 95%CI 0.945–0.973) post-intervention. …"

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

"…<h3>Background</h3><p dir="ltr">Brief intervention is a critical method for identifying patients with problematic substance use in primary care settings and for motivating them to consider treatment options. …"

Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort حسب Mohamed Adil Shah Khoodoruth (14589828)

"…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …"