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Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”
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82
The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar...
Published 2023“…Concerning sleep, 46.1% reported an increase in average sleep duration per day (0.77 h mean increase, 95% CI: 0.66-0.88, P<0.001), and a third of participants reported poorer sleep quality. …”
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83
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. …”
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84
Exploratory risk prediction of type II diabetes with isolation forests and novel biomarkers
Published 2024“…Type II diabetes mellitus (T2DM) is a rising global health burden due to its rapidly increasing prevalence worldwide, and can result in serious complications. …”
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85
Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
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86
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. Functional assays demonstrated an increase in lipid accumulation, bile acid synthesis and glycerol production, while a decrease in glucose uptake, glycogen storage, and Albumin secretion. …”
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87
Critical resolved shear stress for slip and twin nucleation in single crystalline FeNiCoCrMn high entropy alloy
Published 2017“…At 77K, and unlike traditional metallic alloys, an increase in strength, strain hardening rate, and ductility has been reported. …”
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88
Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy
Published 2024“…Results: Our findings reveal several intriguing insights. The sAA levels increased from the first 30 days in confinement to the culmination of the lengthy 240-day mission, suggesting a cumulative impact of stress. …”
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89
Nicotine induces resilience to chronic social defeat stress in a mouse model of water pipe tobacco exposure by activating BDNF signaling
Published 2020“…Finally, we showed that nicotine mediates the effects of WTS only on resilience to stress by increasing BDNF and TRKB levels and signaling. …”
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Implications on Educational Management During the COVID 19 Pandemic
Published 2021“…This study aimed to explore the pandemic's impact on undergraduate students' academic stress, especially as related to their academic performance. …”
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91
α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain
Published 2022“…In this study, we investigated whether aKG has prophylactic and antidepressant effects in chronic social defeat stress and chronic variable stress models of depression, as well as unravel the underlying molecular mechanisms. …”
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masterThesis -
92
Numerical Investigation of Flexural Behavior of Reinforced Concrete (RC) T-Beams Strengthened with Pre-Stressed Iron-Based (FeMnSiCrNi) Shape Memory Alloy Bars
Published 2023“…Based on the numerical results, it was found that increasing the compression strength from 30 to 60 MPa slightly improves the beam’s strength (by 2%), but it significantly increases its ductility by approximately 45%. …”
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93
Application of Cyanobacteria (Roholtiella sp.) Liquid Extract for the Alleviation of Salt Stress in Bell Pepper (Capsicum annuum L.) Plants Grown in a Soilless System
Published 2021“…<div><p>Salinity is one of the abiotic stresses that affect crop growth and productivity in arid and semi-arid regions. …”
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94
Characterization and Modeling of Damage in Steel at Different Strain Rates
Published 2011Get full text
doctoralThesis -
95
An evaluation of sorter induced cell stress (SICS) on peripheral blood mononuclear cells (PBMCs) after different sort conditions - Are your sorted cells getting SICS?
Published 2020“…However, majority of available cell sorters are pressurized, droplet-based systems, which apply significant environmental pressure and shear stress to cells during sorting. Recently, the flow cytometry community has become increasingly aware about the potential negative effects this could have on sorted cells and the term “sorter induced cell stress” (SICS) has been proposed. …”
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96
Causes leading Lebanese teachers to burnout. (c2014)
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97
Implications on Educational Management During the COVID-19 Pandemic
Published 2021“…This study aimed to explore the pandemic's impact on undergraduate students' academic stress, especially as related to their academic performance. …”
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The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells
Published 2023“…Mesenchymal stem cells (MSCs) possess specific properties including the inhibition of apoptosis, oxidative stress, and secretion of trophic factors. These unique properties prompted us to investigate the effect of MSCs conditioned medium (MSCs-CM) on preventing the noxious effects of methylglyoxal (MGO), a precursor of advanced glycated end-products (AGEs) that play a key role in the pathophysiology of diabetes, on endothelial cells with respect to oxidative stress and cell survival. …”