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The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells
Published 2023“…Mesenchymal stem cells (MSCs) possess specific properties including the inhibition of apoptosis, oxidative stress, and secretion of trophic factors. These unique properties prompted us to investigate the effect of MSCs conditioned medium (MSCs-CM) on preventing the noxious effects of methylglyoxal (MGO), a precursor of advanced glycated end-products (AGEs) that play a key role in the pathophysiology of diabetes, on endothelial cells with respect to oxidative stress and cell survival. …”
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Heat Shock-Related Protein Responses and Inflammatory Protein Changes Are Associated with Mild Prolonged Hypoglycemia
Published 2021“…Blood sampling was performed at baseline, hypoglycemia, and 24 h; slow off-rate modified aptamer (SOMA)-scan plasma protein analysis of HSP-related proteins, inflammatory stress markers, and oxidative stress markers was performed. …”
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The Impact of Technostress on Work Engagement
Published 2022“…This thesis hopes that its findings can guide managers and policymakers by contributing to theoretical and empirical evidence on ways to increase employee motivation and improve overall organizational performance.…”
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masterThesis -
106
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…These findings were found to be correlated with increased level of <u>oxidative stress, neuroinflammation,</u> and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating <u>synaptic plasticity</u> integral for promoting learning and memory in the hippocampus. …”
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Evaluation of psychological distress, burnout and structural empowerment status of healthcare workers during the outbreak of coronavirus disease (COVID-19): a cross-sectional quest...
Published 2024“…The results also revealed that direct work with COVID-19 patients, lower work experience, and high workload during the outbreak of COVID-19 increase the risks of negative psychological consequences.…”
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Control of Flow Past an Airfoil Section Using Rotating Cylinders
Published 2015Get full text
doctoralThesis -
109
Ultra high gain step up DC/DC converter based on switched inductor and improved voltage lift technique for high‐voltage applications
Published 2022“…A combination of switched inductor and the conventional voltage lift technique can be used to achieve high gain, but the semiconductor's stress is still high. An improved voltage lift technique by employing an extra diode and capacitor and a switched inductor is proposed, which significantly increases the voltage boosting factor and reduces the voltage stress of semiconductor devices. …”
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Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
Published 2025“…<h3 dir="ltr">Purpose</h3><p dir="ltr">The recreational use of synthetic cannabinoids (SCs) by adolescents and adults has markedly increased in recent years. Previous studies demonstrated that exposure to SCs is associated with multiple adverse health effects. …”
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A Quadratic Non-Isolated High Step-Up Single-Input Dual-Output DC–DC Topology Based on Coupled Inductors with Low Input Current Ripple
Published 2025“…The proposed converter produces high DC output voltages at a low value of duty cycles and low voltage stress across the power MOSFETs. The CIs’ turn ratios give another freedom factor to increase the output voltages and decrease the switches’ stress. …”
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Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats
Published 2023“…<h3>Introduction</h3><p dir="ltr">Oxidative stress is a major instigator of various cardiovascular diseases, including myocardial infarction (MI). …”
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Effects of COVID-19 on Autism Spectrum Disorder in Qatar
Published 2024“…<h3>Introduction</h3><p dir="ltr">The unprecedented impact of the coronavirus pandemic (COVID-19) has had profound implications on the ASD community, including disrupting daily life, increasing stress and emotional dysregulation in autistic children, and worsening individual and family well-being.…”
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Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
Published 2021“…<p dir="ltr">Diabetes-associated long-term hyperglycaemia leads to oxidative stress-mediated fibrosis in different tissues and organs. …”
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The impact of the COVID-19 pandemic on the perinatal mental health of women
Published 2020“…Background data including relevant demographic details, pregnancy and mental health history, concerns, as well as helpful stress-reducing factors reported by women was collected. …”
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Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
Published 2014“…This expression pattern was concomitant with increased inflammatory response in the adipose tissue as monitored by increased levels of Interleukin-6 (IL-6), Tumor necrosis factor-α (TNF-α), and RANTES (P < 0.05). …”
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Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
Published 2018“…<p dir="ltr">Heat shock protein 60 (HSP60) is a key protein in the crosstalk between cellular stress and inflammation. However, the status of HSP60 in diabetes and obesity is unclear. …”
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Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease
Published 2021“…Patient biopsy specimens showed reduced goblet cells; depletion of MUC2, MUC5AC, and MUC6; up-regulation of AGR2; and increased ER stress. The mutant AGR2 showed reduced capacity to bind MUC2 and alleviate tunicamycin-induced ER stress.…”
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Dynamic mechanical characterization and modelling of polypropylene based organoclay nanocomposite
Published 2015“…The experimental characterization was performed by using split Hopkinson pressure bars (SHPB), at different strain rates and temperatures. A significant increase of the yield stress of nanocomposite was shown with the present of organoclay, comparing to neat PP. …”