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421
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
Published 2024“…<h3>Introduction</h3><p dir="ltr">Caloric restriction (CR) is a nutritional intervention that increases life expectancy while lowering the risk for cardio-metabolic disease. …”
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422
Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress
Published 2022“…Our results illustrated that the increasing levels of Cd in the sand, significantly (P < 0.05) decreased shoot length, root length, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, germination percentage, germination index, mean germination time, time to 50% germination, chlorophyll a, chlorophyll b, total chlorophyll and carotenoid contents in all genotypes of B. oleracea. …”
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423
Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes
Published 2023“…Given the aggressive nature and lack of targeted therapies for TNBC, elevated expression of ENO1, FDPS, CCT6A, TUBB2A, and PGK1 predicted worse relapse-free survival (RFS) in basal BC (n = 442), while elevated expression of ENO1, FDPS, CCT6A, and PGK1 was observed in the most aggressive BLIS TNBC subtype. …”
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424
A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle
Published 2022“…These observations were complimented by the 100 ns molecular dynamics simulation and binding free energy analysis, which showed a considerable stability of docked bioflavonoids in the active site of SARS-CoV-2 target proteins. …”
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425
Deep learning-based cross-device standardization of surface-enhanced Raman spectroscopy for enhanced bacterial recognition
Published 2026“…<p dir="ltr">Surface-enhanced Raman spectroscopy (SERS) is a powerful, label-free technique for pathogen detection; however, its broader adoption in clinical diagnostics is hindered by inconsistent spectral quality across portable and laboratory-grade instruments, limited cross-device reproducibility, and the poor generalizability of existing machine learning approaches. …”
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426
Attitudes, motivators, and barriers toward influenza vaccination for children: a study from a conflict-ridden country
Published 2024“…<h3>Background</h3><p dir="ltr">Despite the increased recommendations for influenza vaccination, particularly among high-risk groups such as young children, Yemen lacks an influenza vaccination program, and the influenza vaccine is not included in the national immunization regime. …”
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427
Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up
Published 2022“…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …”
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428
10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes
Published 2020“…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …”
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429
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …”
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430
Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort
Published 2024“…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …”
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431
Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
Published 2020“…Decreased FA along with both increased and decreased MD in different brain regions was present in HUC compared to CHNM. …”
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432
Experimental and modeling analysis of p-type Bi<sub>0</sub>.<sub>4</sub>Sb<sub>1</sub>.<sub>6</sub>Te<sub>3</sub> and graphene nanocomposites
Published 2022“…The synthesized pristine Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> and 0.05wt% GNS/Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> nanocomposites at different addition times of GNS have exhibited a single-phase and artifact-free bulk nanocrystalline Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> with nanocrystals size of 17 nm. …”
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433
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Published 2019“…High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …”
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434
Novel proteins implicated in lipid metabolism disorders
Published 2016“…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …”
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435
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
Published 2021“…Although less important than RH and MR<sub>org/inorg</sub>, the SOA composition plays a second-order role, with differences in the liquid-to-nonliquid transition at moderate MR<sub>org/inorg</sub> of ∼ 1 observed between biogenic-only (anthropogenic-free) and anthropogenic-containing VOC systems. Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼ 0 when GF was larger than 1.15. …”
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436
Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making
Published 2019“…Results Study participants who were invited and completed the survey were 657. The percentage mean score of participants’ attitudes and concern was 70.1 ± 16.4 and 58.3 ± 15.3 respectively. …”
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437
Can Ease of Doing Business Shorten the Distance and Attract Foreign Direct Investment
Published 2021“…Abstract Due to the accelerating pace of globalization, Multinational Enterprises (MNEs) have increasingly employed foreign direct investment (FDI) to enter foreign markets. …”
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438
Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
Published 2019“…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m<sup>2</sup>) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …”
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439
The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar
Published 2023“…</p> <h3>Conclusion</h3> <p>The results of this study suggest that in women with additional risk factors for FGR, the concurrent use of metformin significantly decreases the birthweight and increases the risk for LBW, SFD, PTB and admission to NICU. …”
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440
SYSTEM DYNAMICS APPROACH FOR WHOLE LIFE CYCLE COST MODELLING OF RESIDENTIAL BUILDING PROJECTS IN UNITED ARAB EMIRATES
Published 2020“…The applied adjusting risks are comprising three value levels. Minimum, mean, and maximum cost risks. Simulated costs under adjusting risks' levels can be presented in the same exported data sheet. …”
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