From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease حسب Ahmad Raza (18205961)

"…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …"

Does Ultrasound Really Good Enough to Evaluate the Pneumothorax in the Emergency Department حسب Atilla Temel (17788481)

"…The average age of the patients was 76.5%, with the youngest patient being 18 years old and the oldest one being 90 years old. Of the patients, 45.38% (n = 101) were men. …"

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases حسب Glazer, Evan

"…We hypothesized that PET uptake levels were artificially decreased after chemotherapy. That is, lesions that appeared to be nonmalignant were actually viable malignant lesions.…"
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Effect of chronic and non-chronic moderate wine consumption upon rat lipoprotein profile in the blood. (c2002) حسب Slaiby, Rita

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Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal حسب Zehra Irshad (18614869)

"…We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic drivers and protein targets. Human aortal endothelial cells (HAECs) were incubated in high glucose concentration (20 mM versus 5 mM control) in vitro for 3–6 days. …"

Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health حسب Jinit Masania (7164239)

"…<p>Glycation, oxidation, nitration, and crosslinking of proteins are implicated in the pathogenic mechanisms of type 2 diabetes, cardiovascular disease, and chronic kidney disease. Related modified amino acids formed by proteolysis are excreted in urine. …"

A Scoping Review to Find Out Worldwide COVID-19 Vaccine Hesitancy and Its Underlying Determinants حسب Md. Rafiul Biswas (17293966)

"…., COVID-19 vaccine) and outcome- (i.e., hesitancy) related terms were used to search in these databases. …"

Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO₂ intercooled and reheated cycles under design and off‐d... حسب Wahib A. Al‐Ammari (18877408)

"…The analyses were conducted at relatively low turbine inlet temperatures (TIT: 550–750°C) with compressor inlet temperature (CIT) varied from 33°C (wet‐cooling) to 50°C (dry‐cooling). …"

Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma حسب Abou-Ghazal, Mohamed

"…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
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An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH₄-CO₂-H₂S حسب Hani Ababneh (9218272)

"…However, acid gases have to be removed before the natural gas produced from these fields could be used. One of the novel concepts in this field is the utilization of solid phase formation of carbon dioxide and/or hydrogen sulfide. …"

Past and future climate effects on population structure and diversity of North Pacific surfgrasses حسب Ana I. Tavares (6942986)

"…Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …"

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity حسب Mohamed Abu-Farha (18535590)

"…Thrombospondin 1 (TSP1) was among the proteins that were upregulated in obese subjects and then decreased by physical exercise. Conversely, the histone deacetylase 4 (HDAC4) was downregulated in obese subjects and then induced by physical exercise. …"

Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers حسب Farhat Abbas (5480)

"…Assumptions included that solute displacements through sepiolite porous media and the related simulations represented the phenomenon of saltwater intrusion under non-equilibrium conditions of porous media mimicking the aquifers. …"

Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care حسب Ahmad Kloub (16855149)

"…</p><h3>Methods</h3><p dir="ltr">This observational study compared injured patients admitted one year before (pre-P) and after (post-P) implementing a new VTEp protocol. …"

Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis حسب Mohamed Nabil Elshafei (9960500)

"…</p><h3>Results</h3><p dir="ltr">Six studies, five observational and one randomized (n = 553 patients, out of which 45.7% received advanced therapy), were included in our meta‐analysis. …"

Occurrence and removal characteristics of phthalate esters from bottled drinking water using silver modified roasted date pits حسب Fedae A. Alhaddad (14152161)

"…</p> <h2>Results</h2> <p>The results indicated that the most abundant phthalate esters were DMP followed by DEP under 30 °C; however, DNOP was not detected in any of the tested water samples, except for one sample under 30 °C with a concentration of 0.031 μg/mL. …"

Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c... حسب Rola Abdallah (22484130)

"…ZNE and F6 inhibited metastasis-related cellular processes by modifying cell migration, invasion, and adhesion. …"

Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study حسب Ayman Al-Dahshan (8962568)

"…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …"

Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study حسب Ayman Al-Dahshan (8962568)

"…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …"

Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) حسب Anas Hamad (9545771)

"…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. However, the cancer-related burden on patients, healthcare systems, and the economy is expected to expand; thus, cancer remains a significant public healthcare issue in Qatar. …"