Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

“…<p dir="ltr">Age-related hearing loss (ARHL) is the most common sensory deficit in the elderly. …”

Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... by Hmwe Hmwe, Kyu

“…The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. Global YLLs also decreased substantially, from 186 million (147–221) in 1990 to 51·4 million (39·9–65·9) in 2021. …”
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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”

Modulation of gut microbiota: The effects of a fruits and vegetables supplement by Arun Prasath Lakshmanan (6807152)

“…We enrolled 30 healthy volunteer subjects, matched for age, gender, BMI, and smoking habits, and randomized them into the FVS and the placebo (PLA) groups. …”

Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 by Comfort, Haley

“…Our final dataset comprised 11 different definitions, which were adjusted to match two gestational age thresholds: 20 weeks or longer (reference) and 28 weeks or longer (for comparisons). …”
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Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... by Parkes J Kendrick (9714851)

“…Although global age-standardised prevalence of smoking tobacco use decreased significantly between 1990 and 2019 (annualised rate of change: –1·21% [–1·26 to –1·16]), similar progress was not observed for chewing tobacco (0·46% [0·13 to 0·79]). …”

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Further, chronic Gln accumulation and decreased proteolysis were found to induce the early onset of an age‐related muscle phenotype.…”

Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... by Jaimie D Steinmetz (18015919)

“…Age-standardised prevalence of avoidable blindness decreased by −15·4% [–16·8 to −14·3], while avoidable MSVI showed no change (0·5% [–0·8 to 1·6]). …”

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage by Florence Hariton (18629764)

“…<div><p>Increased cell senescence contributes to the pathogenesis of aging and aging-related disease. Senescence of human fibroblasts in vitro may be delayed by culture in low glucose concentration. …”

Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health by Jinit Masania (7164239)

“…Algorithms combining subject age, BMI, and BCAAs discriminated between healthy controls and impaired metabolic, vascular, and renal health study groups with accuracy of 84%, 72%, and 90%, respectively. …”

Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults by Tarek Ben Hassen (15742605)

“…Indeed, the survey results suggested (i) a change in the modality of acquiring food, consumers reduced the number of shopping trips and buying more on each trip to minimize store visits; (ii) a surge of stockpiling of non-perishable food items; (iii) a shift toward healthier diets; (iv) an increase in culinary capabilities; (v) a decrease of food waste. …”

Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content by Haissam Abou-Saleh (497840)

“…The aim of this study was to determine the dose-dependent effect of a CFO against bone loss in C57BL/6 female mice during aging. Twelve-month old mice were fed with 1% and 4% CFO and 4% safflower oil (SFO) diets, including a group with a 4% regular-FO diet and a group with a lab chow diet for 12 months. …”

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 by Joan B Soriano (6458528)

“…However, when accounting for ageing and population growth, declines were observed in age-standardised prevalence (14·3% decrease), age-standardised death rates (42·6%), and age-standardised DALY rates (38·2%). …”

From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

“…Raised concentrations of glucose in blood can produce advanced glycation end products (AGEs), which further exacerbate neuroinflammation in tandem with the mitigation of neurotoxic Aβ oligomers. …”

Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover by Naila Rabbani (291722)

“…Methylglyoxal forms the major quantitative AGE, hydroimidazolone MG-H1. Glucose and methylglyoxal concentrations in plants change with the developmental stage, senescence, light and dark cycles and also likely biotic and abiotic stresses. …”

The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017 by Arash Etemadi (330880)

“…Globally, 38·2% (21·1–57·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24·5% (20·0–28·9) of the age-standardised DALYs were attributable to smoking in males. …”

Secrecy Performance of a RIS-Assisted Wireless Network: A Comprehensive Analysis Under Outdated CSI by Tasneem Alshamaseen (22392382)

“…This resilience indicates that the system can reduce channel estimation frequency to reconfigure the RIS, thus decreasing overall system overhead and complexity and improving energy efficiency. …”

OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo... by Pia Tohme Khalaf (17425551)

“…<p dir="ltr">This study reveals a significant connection between prenatal bonding or attachment during pregnancy and various factors such as maternal age, anxiety, and stress, including those attributed to specific events like the COVID-19 pandemic. …”

Effect of dietary protein level on gentamicininduced nephrotoxicity in rats and on the circadian rhythms of food ingestion by Zeeni, Nadine

“…In a second study, rats were fed the same diets, however, the treatment given was a sham injection. …”
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Empiric antibiotic therapy of community-acquired Pneumonia at the American University of Beirut Medical Center. (c2001) by Cherfan, Antoine

“…Special attention should be given to decrease hospitalization rate, to preserve fluoroquinolones, and to improve microbiological studies outcome.…”
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