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221
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
Published 2024“…Additionally, we introduced two new metrics to our reporting: prevalence of unsuppressed viraemia (PUV), which represents the proportion of the population without a suppressed level of HIV (viral load <1000 copies per mL), and period lifetime probability of HIV acquisition, which quantifies the hypothetical probability of acquiring HIV for a synthetic cohort, a simulated population that is aged from birth to death through the set of age-specific incidence rates of a given time period. FindingsGlobal new HIV infections decreased by 21·9% (95% UI 13·1–28·8) between 2010 and 2021, from 2·11 million (2·02–2·25) in 2010 to 1·65 million (1·48–1·82) in 2021. …”
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222
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. …”
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223
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
Published 2020“…To characterize variability in lake extents, we analyzed summertime lake area loss (i.e., shrinkage) on two deltas over the past 20 years, using Landsat-derived water masks. …”
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224
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
Published 2024“…The reference forecast is our estimate of the most likely fertility future given the model, past fertility, forecasts of covariates, and historical relationships between covariates and fertility. …”
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225
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”
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226
Total Quality Implementation on Marine Transportation Association Under Natural Disruption of COVID-19 Pandemic
Published 2021“…The spread of COVID-19 infections has brought about remarkable measures confining travel and action interest in all countries. Social distancing, i.e., decreasing collaborations between people to dial back the spread of the infection, has turned into the new standard. …”
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227
Modeling the risk-based decisions of the microgrid in day-ahead energy and reserve markets considering stochastic dispatching of electrical and thermal energy storages
Published 2022“…Also, the risk-based behavior of the MGO showed that increasing the robust parameter decreases the reserve provided for the market and the net power trading with the market. …”
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228
The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature
Published 2021“…Chronic exercise in the form of short-term endurance training (i.e., 12-16 weeks) and long-term combined endurance and resistance training (i.e., 6-12 months) induced increases in salivary SIgA concentration. …”
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229
Effect of climate change on the annual energy consumption of a single family house in British Columbia
Published 2018“…The simulation results show that for both bylaw and PH cases, heating energy consumption will be reduced while cooling energy consumption will be increased, as a result for bylaw case, the energy consumption will be decreased for four climate zones, while for PH case, the energy consumption will be increased for zone 4 & 5 and decreased for zone 6 & 7. …”
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230
Therapeutic targeting of the TPX2/TTK network in colorectal cancer
Published 2023“…<h3>Background</h3><p dir="ltr">While the increased screening, changes in lifestyle, and recent advances in treatment regimen have decreased colorectal cancer (CRC) mortality, metastatic disease and recurrence remains a major clinical challenge. …”
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231
Application of Low-Fermenting Yeast Lachancea thermotolerans for the Control of Toxigenic Fungi Aspergillus parasiticus, Penicillium verrucosum and Fusarium graminearum and Their M...
Published 2018“…Moreover, decreasing yeast nutrient concentrations did not affect the inhibition of fungal growth, but reduced DON synthesis. …”
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232
Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar
Published 2024“…</p><h3>Methods</h3><p dir="ltr">Patient records were retrospectively reviewed during two periods: premature ASP (i.e. the 12 months following ASP implementation (May 2015-April 2016)), and mature ASP (i.e. the last 12 months of a 5-year ASP implementation in Hamad Medical Corporation (HMC) (February 2019-January 2020)). …”
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233
CRISPR-Cas Controls Cryptic Prophages
Published 2022“…We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …”
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234
Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey
Published 2019“…Adherence to PA guidelines seems to be more related to age, BMI, gender (i.e. higher PA adherence in men vs. women), social support (i.e. social deprivation), dietary habits (i.e. fruit and vegetable intake) and social isolation among the elderly. …”
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235
Effect of climate change on the energy performance and thermal comfort of high-rise residential buildings in cold climates
Published 2019“…As a result, for the bylaw case, the total energy consumption would be decreased for two climate zones, while for PH case, the total energy consumption would be increased for zone 4 and decreased for zone 7. …”
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236
Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
Published 2021“…A step further is now required to determine whether these platform foundations should be converted to reefs after their decommissioning (i.e., Rigs to Reefs approach).…”
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237
Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
Published 2022“…Introducing miRNAs, such as miR-294 and miR302/3667, with reprogramming factors, has shown to increase iPSC colony formation. Previously, we identified five transcription factors, GBX2, NANOGP8, SP8, PEG3, and ZIC1, which may boost iPSC generation. …”
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238
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
Published 2022“…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …”
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239
Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging
Published 2022“…While current state-of-the-art oncology imaging techniques have decreased mortality rates, patients still face a diminished quality of life due to treatment. …”
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240
Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment
Published 2020“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
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