Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications by Fang Yu (156838)

“…<p>Loss of function mutations in store-operated Ca²⁺ entry (SOCE) are associated with severe paediatric disorders in humans, including combined immunodeficiency, anaemia, thrombocytopenia, anhidrosis and muscle hypotonia. Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …”

Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM by Ahmed Elrahmani (17128837)

“…<p dir="ltr">Transport of fine particles in porous media has attracted a considerable interest over the past several decades given its importance to many industrial and natural processes. …”

An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School by AL AHMAD, ALAAEDDIN MEHY

“…This is despite the fact that both groups of students are native Arabic speakers, and that both groups of students attend Arabic classes that use the same curriculum and textbooks. Given the high number of British as well as other non-Arabic schools in Dubai, this is a significant issue as many Arabic-speaking students are failing to achieve proficiency in their native language. …”
Get full text

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…These interpretive cognitive acts of meaning construction by leaders and followers include significant elements of conceptual thinking and explanation. …”
Get full text

Implementation of corporate governance rules and procedures in lebanese firms by Elgammal, Walid

“…It also helps the organization to determine the means to achieve its objectives and monitor its performance. …”
Get full text
Get full text
Get full text

An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat... by Merheb, Caroline

“…In both soils, tillage application decreased the densities, the aggregate mean weight diameter, the residual moisture content, and the fine pore volumes while increased the organic matter content, the porosity, the saturated hydraulic conductivity, and the amount of large pores of undisturbed soil. …”
Get full text
Get full text
Get full text

Mitigating the impact of cultural diversity on the innovation process in the private sector in Dubai by HAJI, HASSAN

“…It is true that the aim of any business is to make profit, with decreased profit in the sector many entrepreneurs have discovered other investment schemes which has resulted to more demand of the workforce. …”
Get full text

Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …”
Get full text
Get full text
Get full text

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

“…Additionally, we introduced two new metrics to our reporting: prevalence of unsuppressed viraemia (PUV), which represents the proportion of the population without a suppressed level of HIV (viral load <1000 copies per mL), and period lifetime probability of HIV acquisition, which quantifies the hypothetical probability of acquiring HIV for a synthetic cohort, a simulated population that is aged from birth to death through the set of age-specific incidence rates of a given time period. FindingsGlobal new HIV infections decreased by 21·9% (95% UI 13·1–28·8) between 2010 and 2021, from 2·11 million (2·02–2·25) in 2010 to 1·65 million (1·48–1·82) in 2021. …”
Get full text
Get full text
Get full text

Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

“…In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. …”
Get full text
Get full text
Get full text

Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas by Tejedor, Alejandro

“…To characterize variability in lake extents, we analyzed summertime lake area loss (i.e., shrinkage) on two deltas over the past 20 years, using Landsat-derived water masks. …”
Get full text

Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…The reference forecast is our estimate of the most likely fertility future given the model, past fertility, forecasts of covariates, and historical relationships between covariates and fertility. …”
Get full text
Get full text
Get full text

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”

Total Quality Implementation on Marine Transportation Association Under Natural Disruption of COVID-19 Pandemic by ASAD, NUHA JAMAL

“…The spread of COVID-19 infections has brought about remarkable measures confining travel and action interest in all countries. Social distancing, i.e., decreasing collaborations between people to dial back the spread of the infection, has turned into the new standard. …”
Get full text

Modeling the risk-based decisions of the microgrid in day-ahead energy and reserve markets considering stochastic dispatching of electrical and thermal energy storages by Salah Bahramara (21347576)

“…Also, the risk-based behavior of the MGO showed that increasing the robust parameter decreases the reserve provided for the market and the net power trading with the market. …”

The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature by Maha Sellami (4351159)

“…Chronic exercise in the form of short-term endurance training (i.e., 12-16 weeks) and long-term combined endurance and resistance training (i.e., 6-12 months) induced increases in salivary SIgA concentration. …”

Effect of climate change on the annual energy consumption of a single family house in British Columbia by Mutasim Baba, Fuad

“…The simulation results show that for both bylaw and PH cases, heating energy consumption will be reduced while cooling energy consumption will be increased, as a result for bylaw case, the energy consumption will be decreased for four climate zones, while for PH case, the energy consumption will be increased for zone 4 & 5 and decreased for zone 6 & 7. …”
Get full text
Get full text
Get full text

Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar by Dina Abushanab (10696501)

“…</p><h3>Methods</h3><p dir="ltr">Patient records were retrospectively reviewed during two periods: premature ASP (i.e. the 12 months following ASP implementation (May 2015-April 2016)), and mature ASP (i.e. the last 12 months of a 5-year ASP implementation in Hamad Medical Corporation (HMC) (February 2019-January 2020)). …”

CRISPR-Cas Controls Cryptic Prophages by Sooyeon Song (4891132)

“…We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …”

Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey by Ahmad Salman (3173418)

“…Adherence to PA guidelines seems to be more related to age, BMI, gender (i.e. higher PA adherence in men vs. women), social support (i.e. social deprivation), dietary habits (i.e. fruit and vegetable intake) and social isolation among the elderly. …”