Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype... by Ilham Bettahi (363910)

“…Among the 835 proteins, two showed differential responsiveness to insulin; ATP5F1 protein was decreased, and MYLK2 was higher in the LIS group compared with that in the HIS group. …”

An ensemble-based machine learning model for predicting type 2 diabetes and its effect on bone health by Belqes Alsadi (18695031)

“…No significant negative impact of diabetes progression on bone health was observed over a period of 5-15 yrs in the cohort.</p><h3>Conclusion</h3><p dir="ltr">This study recommends the inclusion of ML model which combines both DXA and clinical data for the early diagnosis of diabetes.…”

Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity by Abu Saleh Md Moin (6189512)

“…A hyperinsulinemic clamp was performed and normoglycemia induced in T2D [4.5 ± 0.07 mmol/L (81 ± 1.2 mg/dl)] for 1-h, following which blood glucose was decreased to ≤2.0 mmol/L (36 mg/dl). …”

Machine Learning-Based Management of Electric Vehicles Charging: Towards Highly-Dispersed Fast Chargers by Mostafa Shibl (18810412)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Energies<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/en13205429" target="_blank">https://dx.doi.org/10.3390/en13205429</a></p>…”

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…</p><h3>Results</h3><p dir="ltr">LAT2KO mice experienced a notable reduction in body weight during fasting (WT:14% and LAT2KO:18%, <i>p</i> = 0.02), with a greater reduction in fat mass (0.5‐fold, <i>p</i> = 0.013) and a higher relative retention of muscle mass (1.3‐fold, <i>p</i> = 0.0003) compared with WT. …”

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study by Rupert Bourne (603842)

“…Globally, between 1990 and 2020, among adults aged 50 years or older, age-standardised prevalence of blindness decreased by 28·5% (–29·4 to −27·7) and prevalence of mild vision impairment decreased slightly (–0·3%, −0·8 to −0·2), whereas prevalence of moderate and severe vision impairment increased slightly (2·5%, 1·9 to 3·2; insufficient data were available to calculate this statistic for vision impairment from uncorrected presbyopia). …”

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal by Zehra Irshad (18614869)

“…</p><p><br></p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41598-019-44358-1" target="_blank">https://dx.doi.org/10.1038/s41598-019-44358-1</a></p>…”

The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women by Thozhukat Sathyapalan (704787)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Endocrinology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fendo.2018.00698" target="_blank">https://dx.doi.org/10.3389/fendo.2018.00698</a></p>…”

Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function by Sahar I. Da'as (17128747)

“…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation‐contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l‐type Ca²⁺ (Ca_v1.2), sodium (NaV1.5) and potassium (KV7.1) channels. …”

The Effect of Experimental Recuperative and Appetitive Post-lunch Nap Opportunities, With or Without Caffeine, on Mood and Reaction Time in Highly Trained Athletes by Mohamed Romdhani (9606357)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Psychology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fpsyg.2021.720493" target="_blank">https://dx.doi.org/10.3389/fpsyg.2021.720493</a></p>…”

The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc... by Thozhukat Sathyapalan (704787)

“…</p><p><br></p><p dir="ltr">ISRCTN Number: ISRCTN24474824</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Endocrinology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fendo.2019.00394" target="_blank">https://dx.doi.org/10.3389/fendo.2019.00394</a></p>…”

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas by Abu Saleh Md Moin (6189512)

“…<h3>Context: </h3><p dir="ltr">Previously, we identified chromograninA positive hormone-negative (CPHN) cells in high frequency in human fetal and neonatal pancreas, likely representing nascent endocrine precursor cells. …”

Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050 by Yingzhao, Jin

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Engineering Novel Single-chain Variable Fragments for Therapeutic and Diagnostic Approaches in Parkinson's Disease by Safa Salim (9186786)

The cost-benefit associated with the maturity of the Antimicrobial Stewardship Program versus prematurity in Heart Hospital of Hamad Medical Corporation in Qatar by Dina Abushanab (10696501)

Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells by Ejlal Abu-El-Rub (5168183)

“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”

Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H₂S: DFT study by Ehab Salih (17075206)

“…Moreover, the adsorption distance (D) between H₂S and Cu/Zn-ZGNR decreased remarkably to 2.23 Å and an S–Cu bond was generated. …”

Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer by Ahmed Mahmoud Mahmoud Mohamed Kardousha (19926096)

“…Although, death rates due to BC have consistently decreased over time, TNBC still poses a challenge due to its poor prognosis, high rates of relapse and resistance to chemotherapy. …”

Crunching the numbers of food poisoning in Qatar by Nature Research (16552612)

“…<p>Salmonellosis is a common type of food poisoning caused by <i>Salmonella</i> bacteria. …”

The immune landscape of solid pediatric tumors by Shimaa Sherif (12862990)

“…</p><h3>Methods</h3><p dir="ltr">We performed a systematic analysis of public RNAseq data (TARGET) for five pediatric tumor types (408 patients): Wilms tumor (WLM), neuroblastoma (NBL), osteosarcoma (OS), clear cell sarcoma of the kidney (CCSK) and rhabdoid tumor of the kidney (RT). …”