Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …"

A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country حسب Nancy Zaghloul (14147865)

"…Among SGLT2is, empagliflozin prescriptions showed an increase from 537 (10.65%) to 2881 (34.40%) compared to dapagliflozin, which decreased by the end of 2018 from 4505 (89.35%) to 5494 (65.6%).…"

Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis حسب Fateen Ata (12217764)

"…The overall SPE-related mortality rate was 8 % (95 % CI: 5.26–10.96). …"

Essays on the effect of excess compensation and governance changes on firm value حسب Dah, Mustafa A.

"…Our results suggest that an increase in director excess compensation decreases the likelihood of CEO turnover, reduces the turnover-performance sensitivity, and increases managerial entrenchment. …"
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Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful? حسب Abdalla, Eddie K.

"…Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …"
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Vitamin D association with coagulation factors in polycystic ovary syndrome is dependent upon body mass index حسب Abu Saleh Md Moin (6189512)

"…It is reported that PCOS subjects show marked platelet dysfunction and decreased plasma fibrinolytic activity, resulting in a prothrombotic state. …"

A simple quality-of-service-based connection setup management approach for optical networks حسب Abou-Rjeily, C.

"…One of the major challenges for optical network operators is related to realizing profitable networks that preserve the overall satisfaction of their end customers. …"
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Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim, Al-Fahdawi

"…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …"
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Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression حسب Rayanah Barnawi (8737584)

"…<p dir="ltr">Recent years have witnessed major progress in development of novel therapeutic agents such as chemotherapy, targeted therapy and immune checkpoint inhibitors for breast cancer. However, cancer-related death remains high especially in triple-negative breast cancer (TNBC) due limited therapeutic options. …"

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 حسب Razieh, Hassannejad

"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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دور مكاتب الإصلاح والوساطة والتوفيق الأسري في الأردن في الحد من النزاعات الأسرية من وجهة نظر العاملين بها... حسب Al-Oqaili , Amneh Irshied

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Novel proteins implicated in lipid metabolism disorders حسب Nature Research (16552612)

"…After feeding, its expression is decreased, promoting the uptake of dietary lipids in fat tissue. …"

The Moderating Role of Training in the Relationship between Knowledge Management and Innovation حسب Fadel, Reem

"…Results indicated that knowledge acquisition, knowledge application and knowledge protection are significantly and positively related to the two dimensions of innovation: behavior innovation and strategic innovation. …"
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The Use of Cutting-Stone-Slurry-Waste in Engineering Practice حسب Attom, Mousa

"…Results indicated that mixing the clay soil with cutting stone slurry waste increased the max dry density, and decreased the optimum water content percent and the plasticity index. …"
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Oxandrolone Treatment in Adults with Severe Thermal Injury حسب Btaiche, Imad F.

"…However, most data on oxandrolone use in adult patients with severe thermal injury are derived from single-center studies, many of which enrolled a relatively small number of subjects and some of which had a poor design. …"
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Properties and Microstructure Distribution of High-Performance Thermal Insulation Concrete حسب Malek Mohammad (17150977)

"…This material allows for better thermal insulation properties, thus decreasing the energy usage within the life cycle of the concrete structure. …"

The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms حسب Farah Karam (22330564)

"…<p dir="ltr">Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …"

SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs حسب Raed Shalaby (3756112)

"…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…"

Frugal innovation for sustainable rural development حسب Mokter Hossain (14634969)

"…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …"

TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power حسب Mahmoud, Rana

"…Increasing power dissipation may lead to decreasing system effciency and lifetime. The BULK metal oxide semiconductor field-effect transistor (MOSFET) has relatively high power dissipation and low frequency response due to its internal capacitances. …"
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