Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity by Mohammed R. Shaker (10316180)

“…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …”

Characteristics of aerosols and planetary boundary layer dynamics during biomass burning season by Muhammad Zeeshaan Shahid (18131689)

“…The planetary boundary layer (PBL) height, measured with Ceilometer LIDAR, showed decreasing trend in height from October to December that support aerosol accumulation near the surface during the the month of November. …”

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas by Abu Saleh Md Moin (6189512)

“…</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">CPHN cell frequency decreased 84% (islets) and 42% (clusters) from fetal to infant life. …”

Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…The global annualised rate of decline in the DALY rate was greatest in children younger than the age of 10 years. …”
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Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas by Tejedor, Alejandro

“…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…”
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Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells by Hafsa Madni (22674428)

“…Foxa-2 is also expressed in the adipocytes of mice with high-fat diet-induced obesity, and its haploid sufficiency leads to increased adipogenesis, lipid accumulation, and increased fat mass. However, the role of FOXA2 in human adipocytes has not been studied. …”

Improving the performance of a commercial absorption cooling system by using ejector: A theoretical study by Hamza K. Mukhtar (17821004)

“…The model was developed based on mass, concentration, and energy balance equations, in addition to heat transfer equations. …”

Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States by Abdul Ahad (545575)

“…</p><h3>Results</h3><p dir="ltr">Overall AAMR was 54.3 in 1999 and 34.6 in 2019. After a decline in AAMR from 1999 to 2015, an alarming rise in mortality was observed until 2019. …”

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

“…It is observed that the flow velocity decreases with the increase in the Hartmann number that signifies the magnetic field. …”

Factors Associated with Meeting Current Recommendation for Physical Activity in Scottish Adults with Diabetes by Ahmad Salman (3173418)

“…Furthermore, meeting the recommended physical activity levels decreased with age (OR 0.96; 95% CI 0.95–0.97), having a longstanding illness (OR 0.56; 95% CI 0.34–0.93) and body mass index (OR 0.94; 95% CI 0.92–0.97), but increased with higher fruit and vegetable intake (OR 1.16; 95% CI 1.07–1.25) and mental wellbeing (OR 1.04; 95% CI 1.02–1.06). …”

Examining time-to-transport decisions in Emergency Medical Services by Hassan Farhat (9000509)

“…</p><h3>Conclusion</h3><p dir="ltr">The study elucidates and clarifies key factors affecting time-to-transport in EMS, underscoring a decline in transport success rates as time on scene lengthens. …”

Influence of co-current vapor flow on falling film over horizontal tube by Furqan Tahir (14429547)

“…The vapor flow exerts external force on falling film and affects film hydrodynamics, heat and mass transfer. This study focuses on analyzing the effects of co-current vapor flow on falling film distribution and hydrodynamics. …”

Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey by Ahmad Salman (3173418)

“…Also, meeting recommended PA decreased with age [OR 0.92 (95% CI 0.90–0.94)] and body mass index [OR 0.93 (95% CI 0.91–0.95]; but increased per additional portion of fruit and vegetables taken [OR 1.19 (95% CI 1.12–1.25)] and with increase in well-being scale score [OR 1.05 (95% CI 1.03 to 1.06)]. …”

The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review by Sara Sokary (17337724)

“…Spirulina was effective in reducing body weight, body mass index, and waist circumference, with a potential dose-dependent effect. …”

Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS by Anna Halama (545988)

“…IS was lower in PCOS (p < 0.001) and was further decreased by the lipid infusion in both PCOS and controls. …”

Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine by Mariam Ahmed Amin Mohamed Elesnawy (21547187)

“…Immunoprecipitation (IP), followed by mass spectrometry (IP-MS) of <i>LDHC</i> stably silenced MDA-MB-468 breast cancer cells identified three potential LDHC binding partners with reported roles in genomic integrity and cancer: TUBA1B, PKM2 and hnRNPM. …”

Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome by Abu Saleh Md Moin (6189512)

“…Cohorts were age matched, though PCOS had elevated body mass index (p < 0.001), insulin (p < 0.001) and C-reactive protein (CRP) (p < 0.0001). …”

The promise of tirzepatide: A narrative review of metabolic benefits by Sara Sokary (17337724)

“…Furthermore, limited evidence showed that lost body weight may be primarily due to fat mass reduction. Tirzepatide also significantly decreased food intake, reduced overall appetite scores and increased fasting visual analog scale scores for satiety and fullness across different clinical trials. …”

Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy by Abu Saleh Md Moin (6189512)

“…</p> <h2>Conclusions</h2> <p>Our findings of no increase in CPHN cell frequency in pancreas of pregnant women suggest that this potential β-cell regenerative mechanism is not that by which the increased β-cell mass of pregnancy is achieved. However, an increase in the percentage of clustered β-cells was found in pregnancy, with decreased frequency of other endocrine cells in clusters, suggesting a compensatory shift from other pancreatic endocrine cell types to β-cells as a mechanism to meet the increased insulin demands of pregnancy.…”

Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study by Zlatan Zvizdic (9212371)

“…The most common symptoms were pain (abdominal and inguinal) and inguinal mass with no palpable testis in the ipsilateral hemiscrotum. …”