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601
From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
منشور في 2025"…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …"
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602
COVID-19 may have increased global support for universal health coverage: multi-country observational study
منشور في 2023"…Trust in the government to deal with COVID-19 decreased over time, and this negative trajectory predicted a demand for better future government intervention in healthcare (ß = −0.10, <i>p</i> = 0.0003).…"
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603
The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort
منشور في 2019"…Specific CFO-related running mechanical adjustments included a reduced braking impulse occurring in the first 25% of contact time with EVA, whereas wearing TPU increased propulsive loading rate.…"
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604
Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish
منشور في 2019"…It enables practical real time visualization in a non-invasive manner, making the modality especially useful to image dynamic cardiac structures. …"
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605
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606
An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH<sub>4</sub>-CO<sub>2</sub>-H<sub>2</sub>S
منشور في 2021"…Overall, it was found that separation of CO<sub>2</sub> in solid phase improves when increasing the operating pressure up to 20 bar, and decreases at higher temperatures. Similarly, the separation of H<sub>2</sub>S in either liquid or solid phase improves at higher pressures and lower temperatures. …"
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607
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
منشور في 2024"…Cortical bone, however, was decreased in young mice on CR and remained reduced in aged mice, irrespective of dietary intervention. …"
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608
Past and future climate effects on population structure and diversity of North Pacific surfgrasses
منشور في 2024"…Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …"
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609
Biomarkers show promise for treatment of heart valve disease
منشور في 2015"…The researchers suggest that patients with increased pro- or decreased anti-calcific factors in their serum should avoid replacement with a bioprosthesis. …"
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610
Tailoring the deposition of MoSe<sub>2</sub> on TiO<sub>2</sub> nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting
منشور في 2023"…The photoelectrochemical properties of the heterojunction were explored and optimized as a function of the thickness of the MoSe<sub>2</sub> layer, which was controlled by the sputtering time. The MoSe<sub>2</sub> grows perpendicularly on TiO<sub>2</sub> NRs in a 2D layered structure, maximizing the exposed active edges, an essential aspect that permits maximum exploitation of deposited MoSe<sub>2</sub>. …"
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611
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612
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
منشور في 2023"…We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. …"
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613
Glycemic outcomes of Advanced Hybrid Closed Loop system in children and adolescents with Type 1 Diabetes, previously treated with Multiple Daily Injections (MiniMed 780G system in...
منشور في 2022"…The primary outcome of the study was the change in the time spent in the target in range (TIR) of 70–180 mg/dl and HbA1c from baseline (MDI + CGM, 1 week) to study phase (AHCL, 12 weeks). …"
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614
Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …"
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615
Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…</p><h3>Results </h3><p dir="ltr">Out of 5639 patients screened, 75.5% (95% CI: 74.3–76.6) were exposed to polypharmacy. Females were 1.18 times more likely to have polypharmacy compared to males (95% CI: 1.03–1.34). …"
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616
Exergames versus self-regulated exercises with instruction leaflets to improve adherence during geriatric rehabilitation: a randomized controlled trial
منشور في 2017"…Adherence was comparable at day one (38 min. in the EG and 42 min. in the CG) and significantly higher in the CG at day 10 (54 min. in the CG while decreasing to 28 min. in the EG, <i>p</i> = 0.007, ES 0.94, 0.39–0.151). …"
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617
Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare
منشور في 2021"…The results revealed that the new tool is beneficial, and the median times to finish the processes within the patient’s journey have significantly decreased. …"
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618
Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud...
منشور في 2020"…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …"
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619
Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
منشور في 2022"…Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. …"