A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... by Abou-Ghazal, Mohamed

“…Long-term survival (>78 days) was observed in 80% of mice with established intracerebral syngeneic melanoma treated with 40 mg/kg of WP1066 in contrast to control mice who survived for a median of 15 days. Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …”
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Incidence of Sedation-Related Complications With Propofol Use During Advanced Endoscopic Procedures by Azar, Riad

“…We performed a regression analysis to compare characteristics of patients requiring AMs (AM+) with those who did not (AM−). Results A total of 799 patients were enrolled over 7 months. …”
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Initial risk assessment for pulmonary hypertension in patients with COPD by Yammine, Joe

“…Background Pulmonary hypertension (PH) is a comorbidity associated with increased mortality in chronic obstructive pulmonary disease (COPD) patients. …”
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Patterns of Rectal Temperature and Shipping Fever Incidence in Horses Transported Over Long-Distances by Yousuke Maeda (18174976)

“…Clinical signs of shipping fever was observed in 25 of the 53 horses (47.2%), of which 10 horses (18.9%) exhibited fever at the end of transportation and 15 horses (28.3%) did not. This showed that horses that develop shipping fever do not necessarily present with fever at the end of transportation. …”

Non-medical cancer support for Qatari women by Nature Research (16552612)

“…<p>Patients' perceptions of the importance of psychosocial support is becoming increasingly important for improving the quality of patient-centred care, but information about the attitudes of female cancer patients in Arab and Muslim populations is scarce. …”

The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects by Ilhame Diboun (3522413)

“…<p dir="ltr">Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complications. …”

Enhancing eggplant (Solanum melongena L.) yield and water use efficiency through optimized irrigation and nitrogen practices in open field conditions by Adewale Suraj, Bello

“…While average fruit weight did not differ significantly across nitrogen levels, the highest fruit yield was recorded under F1 and F2 treatments. …”
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Development and Validation of the Motivation for Tutoring Questionnaire in Problem-Based Learning Programs by Salah Eldin, Kassab

“…In addition, tutoring efficacy scores significantly increased by years of tutoring experience and predicted 38% of the variance in self-rated tutoring skills scores. …”
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Schizophrenia-related dysbindin-1 gene is required for innate immune response and homeostasis in the developing subventricular zone by Abeer R. Al-Shammari (11405339)

“…Immunohistochemistry showed higher Iba1+ immune cell density in the SVZ of Sdy mice than in WT postnatally. PolyI:C did not alter SVZ Iba1+ cell density but increased CD45+/Iba1− cell numbers in the SVZ of Sdy mice. …”

Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies by Umar Nawaz Kayani (17131781)

“…The non-linear models yielded more significant findings, while the linear models did not indicate any significant effects of exchange rate volatility on trade flows. …”

Exploring beyond numeric weight loss: The metabolic effects of semaglutide by Sara Sokary (17337724)

“…</u> It also significantly reduced ad libitum <u>energy intake</u>, decreased hunger, and increased satiety in multiple trials. …”

Unravelling the predictors of late cancer presentation and diagnosis in Jordan: a cross-sectional study of patients with lung and colorectal cancers by Damsees, Rana

“…For colorectal cancer, those having no previous knowledge about cancers or screening programmes had increased odds of reporting late diagnosis (2.30, 95% CI 1.06 to 4.97). …”
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Development of industrially viable geopolymers from treated petroleum fly ash by Mohammad A. Al-Ghouti (8882054)

“…It was concluded that the petroleum fly ash did tend to form successful stable geopolymers with high compressive strength and water absorption.…”

The Efficacy of Lubiprostone in Patients of Constipation: An Updated Systematic Review and Meta‐Analysis by Umar Akram (20151411)

“…In opioid‐induced constipation (OIC), lubiprostone increased SBM within 24 h (RR 1.277, 95% CI 1.105–1.475) but did not significantly affect abdominal pain (RR 4.321, 95% CI 0.624–29.941). …”

Effect of chronic and non-chronic moderate wine consumption upon rat lipoprotein profile in the blood. (c2002) by Slaiby, Rita

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Raising awareness among health educators and educational institutions of the need to overcome the language barrier among Non-Native English speaking students of Health Sciences in... by Ghizlane Bendriss (9025832)

“…This study showed a decrease in 2014 for the proportion of students in the foundation year that studied sciences in English with 73% in 2013 to 39% in 2014. …”

DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations by El Maarri, Osman

“…The X inactivation process appears to be less effective in Klinefelter syndrome as methylation on the X was decreased compared to normal female samples. …”
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The risk of chromium picolinate supplementation in normolipidemic rats fed regular or high fat diet. (c2005) by Bou Farah, Helena

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Road safety and traffic medicine in Iran: Achievements and challenges by A. Motevalian (19807242)

“…The number of annual fatalities, which had been on the rise for several decades, reached to the maximum number of over 27500 deaths in 2005. The number decreased to 23000 in 2010 and less than 18000 in 2013. …”

Self-Reported Sleep and Exercise Patterns in Patients with Schizophrenia: a Cross-Sectional Comparative Study by Nancy Kiwan (12451992)

“…Patients with schizophrenia have shown abnormal sleep patterns and decreased physical activity that were linked to their psychopathology and physical health. …”