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541
The changing landscape in the treatment of metastatic castration-resistant prostate cancer
منشور في 2012"…The past few years have brought increasing advances in the therapeutic management of metastatic castration-resistant prostate cancer with the approval of several agents, including vaccine therapy with sipuleucel-T, second-line chemotherapy with cabazitaxel, the bone-targeted pharmaceutical denosumab, and the novel antiandrogen therapy abiraterone acetate. …"
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article -
542
The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
منشور في 2020"…Finally, we looked at the effect of HuArgI (Co)-PEG5000 on 3D motility of the ovarian cancer cell line, using a collagen based assay. It showed that SKOV3 cell line does not show significant invasiveness to collagen. …"
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masterThesis -
543
Emerging therapies in multiple myeloma
منشور في 2015"…However, despite the increased effectiveness of the first-line agents, the majority of patients will eventually relapse and become drug resistant. …"
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article -
544
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545
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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546
Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors
منشور في 2022"…In the National Cancer Institute human tumor cell line screen, BBGD was most active against the glioblastoma SNB-19 cell line. …"
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547
PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer
منشور في 2019"…Gene ontology analyses revealed enrichment of genes that are dysregulated in ovarian and esophageal cancer and are involved in transcription and apoptosis. In line with this, interrogation of TCGA and GTEx data demonstrated an increased PRAME expression in ovarian and esophageal tumor tissues in addition to breast tumors where it is associated with worse survival. …"
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548
Modeling and Performance Analysis of mmWave and WiFi-Based Vehicle Communications
منشور في 2024"…This study explores a comparative analysis of mmWave and WiFi transmission technologies, with a specific focus on line-of-sight (LoS) and non-line-of-sight (NLoS) scenarios in both 2D and 3D modeling environments. …"
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549
3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction
منشور في 2022"…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …"
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550
Lyapunov-Function-Based Controller for Single-Phase NPC Quasi-Z-Source Inverter with 2<em>ω</em> Frequency Ripple Suppression
منشور في 2020"…Furthermore, the modified simple boost control technique is proposed to eliminate the double-line frequency ripples in the quasi-impedance source inductor currents and minimize the double-line frequency ripples in the quasi-impedance source capacitor voltages. …"
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551
The history and development of newspaper electronic pagination systems in the United States, 1975-1987
منشور في 1990"…This was perhaps, due to the unevenness with which the total pagination process has developed, and the continuing problems involved in merging line-art and graphics with text. Increased computer storage space and other advances may solve this problem soon, and satellite transmission of graphic art for national advertisements, to specific newspapers is a new development being planned for the near future.…"
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masterThesis -
552
Marketing communications
منشور في 2010"…Sponsorship has become increasingly popular - within companies that operate in consumer markets. …"
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article -
553
Analysing the State of Inclusive Education in China: Challenges and Perspectives
منشور في 2025"…Key recommendations include ongoing monitoring, clear policy directives, increased family involvement, and enhanced teacher training. …"
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554
Students at risk of academic failure: Could differentiated instruction be a catalyst for school reform?
منشور في 2022"…One of the main motivations and intent for undertaking this line of research is due to the sustained concern around the continuously increasing rates of attrition among students in the Caribbean. …"
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555
Harmonic flow study and evaluation of a petrochemical plant in Saudi Arabia
منشور في 2002"…Nowadays, the concern about power quality is continuously increasing, due to industry automation and use of nonlinear devices introduced in the power system. …"
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article -
556
Interactions between riluzole and ABCG2/BCRP transporter
منشور في 2009"…After repeated doses of riluzole, BCRP activity was increased in CF1 mdr1a (−/−) mice, riluzole uptake was decrease and both BCRP expression and activity were increased in BeWo cells. …"
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article -
557
Sequence MAP decoding of trellis codes for Gaussian and Rayleighchannels
منشور في 1999"…Sequence MAP decoding is shown to substantially improve performance under very noisy channel conditions for systems with low-to-moderate redundancy, with relative gain increasing as the rate increases. As a result, coding schemes with multidimensional constellations are shown to have higher MAP gains than comparable schemes with two-dimensional (2-D) constellations. …"
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article -
558
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559
The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports
منشور في 2024"…Our results substantiated that MDPHP and MDPV similarly affect sensorimotor and behavioural responses in mice, importantly increased locomotion and induced aggressive behaviour, and, at higher dosage, increased heart rate and blood pressure. …"
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article -
560
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
منشور في 2022"…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …"