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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…Melanoma is a common and deadly tumor that upon metastasis to the brain, survival is less than one year. Development of new, effective therapies for metastatic melanoma that target novel pathways associated with the genesis of metastatic disease is a major unmet clinical need. …”
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322
A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
Published 2022“…As the drill pipe rotational speed increased, the pressure drop decreased slightly until a critical rotatory speed was reached, thereafter, the pressure drop increased markedly. …”
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323
Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications
Published 2025“…It was found that increasing ZiF-8 decreases the swelling in different media and increases degradation in PBS media. …”
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324
Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
Published 2022“…</p><h3>Results</h3><p dir="ltr">The BCL2 gene was found to be less expressed in both IM and (HU + IM) treatments as compared to the HU group alone, while PP2A gene expression was raised. …”
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325
Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
Published 2019“…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m<sup>2</sup>) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …”
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326
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
Published 2021“…Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼ 0 when GF was larger than 1.15. …”
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327
Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis
Published 2025“…There was no significant difference in the safety outcomes (major and minor bleeding events), with a trend towards a decreased risk among direct oral anticoagulant treated cohorts (OR 0.3, 95% CI 0.08–1.1) and (OR 0.64, 95% CI 0.24–1.7), respectively.…”
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Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review
Published 2023“…<p dir="ltr">Microchannel heat exchangers are heat exchangers with a tube diameter of less than 1 mm. Conventional cooling approaches such as the forced‐air cooling technique fail in high technological compact systems because of the small‐sized surfaces of chips and circuits. …”
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329
Theoretical insight into effect of cation–anion pairs on CO<sub>2</sub> reduction on bismuth electrocatalysts
Published 2020“…The adsorption energy (Eads) and work function (Wf) of the anions increases with decreasing anion size (i.e., Cl<sup>−</sup> > Br<sup>−</sup> > I<sup>−</sup>). …”
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330
Can bitcoin’s volatility be tamed?
Published 2018“…Bitcoin is a software for operating a peer-to-peer payment network with its own hard money, without having to rely on a trusted third party. …”
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331
Implementation of corporate governance rules and procedures in lebanese firms
Published 2014“…It also helps the organization to determine the means to achieve its objectives and monitor its performance. …”
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332
Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study
Published 2019“…First, we produced results on incidence, prevalence, years lived with disability, deaths, years of life lost and disability-adjusted life years from 1990 to 2017 for 195 countries and territories. …”
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333
Essays on international environmental policy
Published 2009“…My essay, investigates one possible market-based remedy to this problem, namely a "spatial" tax on farming activities which decreases as such activities take place farther upstream away from the population center. …”
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334
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
Published 2018“…This is in addition to the other effect represented by reducing the direct solar access to the building surfaces and decreases the solar energy gained by the buildings envelop through direct radiation. …”
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335
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Published 2020“…Premature mortality from chronic respiratory diseases seems to be highest in regions with less-resourced health systems on a per-capita basis. …”
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336
Mitigating the impact of cultural diversity on the innovation process in the private sector in Dubai
Published 2017“…The writer (2016), notes that the oil product has been on the decline, these has led to less aggressiveness in the field and hence fetching low prices. …”
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A nonlinear PID servo controller for computer hard disk drives
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339
Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd...
Published 2021“…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global U5MR decreased from 71·2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68·3–74·0) in 2000 to 37·1 (33·2–41·7) in 2019 while global NMR correspondingly declined more slowly from 28·0 deaths per 1000 live births (26·8–29·5) in 2000 to 17·9 (16·3–19·8) in 2019. …”
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Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
Published 2024“…BackgroundDiarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. …”
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